Andrew Craig

Transcriptional Circuitry in HGSOC: A Dynamic Three-State Model Informed by a Living Biobank of Purified Tumour Fractions https://www.biorxiv.org/content/10.1101/2025.07.18.665513v1

Frank's last post. Not surprising that it is supporting and boosting colleagues.

Rest in peace, Frank. Thanks for making the world a little brighter for those who knew you.

Tomlinson: Flood deaths were preventable — but officials ignored the warnings "Climate scientists warned of worsening floods, and local officials knew the risk but decided $1 million was too high a price," columnist Chris Tomlinson writes.

"Texans should be disgusted with politicians who keep asking, 'How could we have known?' when scientists and activists have been warning them. For too long, our Republican leaders have been putting their hands over their ears and shouting, 'la-la-la, I can’t hear you!'”

Advancing cancer research via comparative oncology - Nature Reviews Cancer Comparative oncology combines evolutionary biology, ecology, veterinary medicine and clinical oncology to better understand cancer, for example, by identifying the molecular and cellular mechanisms un...

Enjoyed this @natrevcancer.nature.com article on comparative oncology - how we can learn from other species 🐘🐋🦜🐍 about ways to prevent (& possibly treat) cancer. Both a review and a call to action for the research community. www.nature.com/articles/s41... @atjcagan.bsky.social @cmaley.bsky.social

CIHR NoR day is always rough. Nice to get discussed and some positive feedback. We put so much time and effort into grant applications, and reviewers work so hard to give them a chance. Too bad there is so little money in the pot - I remember the days when a 4.0 score was funded!

I watched @mark-carney.bsky.social Canada Day speech togday about 🇨🇦’s strengthening unity. It’s fitting he meet with Darrell Fox. @terryfoxfoundation.bsky.social’s
@marathonofhope.bsky.social is unifying Canada’s cancer community to accelerate precision medicine, by Canadians, for Canadians 🇨🇦!

Proposed cuts could have ‘catastrophic effect,’ 110 biomedical, health sciences industry leaders tell Congress Proposed cuts will have “a catastrophic effect on the advancement of biomedical and biotechnology capabilities in the United States,” more than 100 leaders of biomedical/health sciences companies tell...

Much appreciated support from biotech execs and investors 🙏

www.statnews.com/2025/06/27/b...

Based on a first-in-human phase I trial in patients with metastatic melanoma, Hodi et al. reported safety and feasibility of WDVAX, a macroporous poly-lactide-coglycolide matrix polymer scaffold incorporating cytokine GM-CSF [...] bit.ly/44z7rFU  ‪@danafarber.bsky.social‬

This was absolutely my experience when I started at NIH in 2003.

I was very impressed with how well run things were compared to my experiences in both academia and the private sector.

YouTube video by Science Communication Lab The Most Beautiful Experiment: Meselson and Stahl

Just learned that Frank Stahl (of the Meselson and Stahl DNA replication experiment ("the most beautiful experiment in biology") died at the beginning of April, to no fanfare. Here's a lovely video of them reminiscing: www.youtube.com/watch?v=7-tn...

For some of us, every day is RET day! Thanks to my awesome alumni. You have all grown so much and reached so far!

It was as a RET-union for past and present @mulliganlab.bsky.social and some wannabes like me @sinclaircri.bsky.social last Friday. Quite an impressive scope and diversity of research contributions! 👏🎉😁

Led by Terry Fox's brother, cyclists stop in Thunder Bay, Ont., on National Ride of Hope | CBC News A team of eight cyclists, led by the late Terry Fox's younger brother, is riding across the country with the goal of raising $1 million for cancer research. They were greeted by dozens of people in Th...

Led by Terry Fox's brother, cyclists on National Ride of Hope riding cross-Canada to raise $1 million for #cancer research. Team makes emotional stop at Thunder Bay memorial, where Terry was forced to end Marathon of Hope run. www.cbc.ca/news/canada/... @cbcnews.ca @terryfoxfoundation.bsky.social

"Innovation, Science and Economic Development Canada did not provide an interview or comment to CBC."

© CBC/Radio-Canada 2025. All rights reserved.

"Scientific Sovereignty — How Canadian scientists are coping with U.S. cuts and chaos" My MD/PhD student @kevinterleukin.bsky.social an I discuss how our work on sex differences in immune responses has been affected (start at 36:10 for us but full episode very worth while)
www.cbc.ca/listen/live-...

Trump just declared war on Iran unilaterally in a direct violation of the Constitution. The Republicans in Congress will just roll over and Fox News will cover his ass.

Emerging mechanomedicines informed by mechanotransduction along the integrin–cytoskeleton–nucleus axis Mechanical forces are fundamental to the formation of normal biological tissues and the maintenance of physiological health. These forces are transmitted from t

Emerging mechanomedicines informed by mechanotransduction along the integrin–cytoskeleton–nucleus axis
pubs.aip.org/aip/apb/arti...

Fantastic day talking drug discovery with our colleagues @oicr.on.ca hosted @sinclaircri.bsky.social

How many ways can you be unfit?

does he ... does he think the UK is still part of the EU?

BREAKING: A federal judge in Massachusetts (the Reagan-appointed William Young) has declared the Trump administration's cuts to NIH grants — ostensibly over Trump's EOs on gender ideology and DEI — are "illegal" and "void." He's ordering many grants restored.

MIND is a world-leading collaboration between the Western Advanced Microscopy core using lightsheet microscopy and the Centre for Functional and Metabolic Mapping @cfmm.bsky.social @neuroak.bsky.social

My message to Trump’s NIH Director? No one in America wants us to do LESS cancer research.

No one is asking Trump to make it harder to cure Alzheimer's disease.

Yet Trump is cutting all of this NOW and demanding an $18 BILLION cut to NIH next year. Not on my watch.

Climate, war, pathogens/pandemics - the three existential threats to humankind - are being hastened upon us by decisions being taken by US and others. I would hope all three areas become the focus of new, strong international alliances in the weeks and months ahead.

Early morning thought

Look at that little tiny red bar for May 2025.

That's the illegal rescission/impoundment of Congressionally appropriated funds, shown graphically.

3900 grants that DOGE has killed in May. Trump is killing American science and ending disease cures. Come out to protests June 14th, everyone.

NIH scientists publish “Bethesda Declaration” rebuking Trump admin The letter is modeled after the NIH director’s controversial “Great Barrington Declaration.”…

ArsTechica story about #BethesdaDeclaration up now

arstechnica.com/health/2025/...

President's essay: We are science, and science is crucial | Cold Spring Harbor Laboratory At Cold Spring Harbor Laboratory (CSHL), we deeply value our uniquely vibrant campus and culture. But we thrive because we are intensely engaged with the broad community of scientists across the Unite...

President & CEO Bruce Stillman reflects on decades of scientific progress & issues a call to action. As public funding declines & immigration policies tighten, the future of innovation is at risk. The U.S. must continue investing in science & the people behind it. www.cshl.edu/presidents-e...

The #CCTG MA40 FINER clinical trial presented at #ASCO25 shows promise in slowing advanced breast cancer progression - highlighting the importance of targeting the AKT pathway to slow tumour progression in advanced estrogen receptor-positive (ER+)/HER2-negative #breastcancer. buff.ly/jm31zwm