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AJ Simon

@ayejaysimon.bsky.social

Neuroscience PhD candidate at Yale Brain networks, cognition, psychiatry Constable Lab NSF GRFP fellow Formerly @Neuroscapeucsf Twitter: @ayejaysimon

124 Followers  |  244 Following  |  9 Posts  |  Joined: 04.12.2024  |  1.9476

Latest posts by ayejaysimon.bsky.social on Bluesky

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Multivariate environmental exposures are reflected in whole-brain functional connectivity and cognition in youth | bioRxiv www.biorxiv.org/content/10.1...

16.11.2025 23:01 β€” πŸ‘ 15    πŸ” 8    πŸ’¬ 0    πŸ“Œ 0
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Congrats, great choices for Cogneuro research:

29.10.2025 14:02 β€” πŸ‘ 54    πŸ” 7    πŸ’¬ 2    πŸ“Œ 1

Great piece by @natolambert.bsky.social on the current state of human exhaustion in the AI world. Makes this important point:

25.10.2025 15:05 β€” πŸ‘ 27    πŸ” 8    πŸ’¬ 2    πŸ“Œ 1
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BOLD signal changes can oppose oxygen metabolism across the human cortex | bioRxiv www.biorxiv.org/content/10.1...

22.10.2025 00:41 β€” πŸ‘ 24    πŸ” 11    πŸ’¬ 1    πŸ“Œ 2

Excited to share our new preprint! We conducted a spatial meta-analysis of community violence and mental health, synthesizing 155 articles (k = 769) to test how exposure to community violence is associated with mental health problems, and how state social service investments moderate the link. πŸ’΅

20.10.2025 13:30 β€” πŸ‘ 8    πŸ” 3    πŸ’¬ 1    πŸ“Œ 1
Cross-species mapping of psychedelic gene expression reveals links to the 5HT2A receptor, cortical layers, and human accelerated regions Psychedelic drugs exert rapid and profound effects on human consciousness and are increasingly explored for their clinical potential. Yet, the genetic programs through which psychedelics reshape brain...

Really cool interdisciplinary study!

www.researchsquare.com/article/rs-7...

20.10.2025 03:06 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Excited to share our new paper entitled Multisystem Environmental Factors Elucidate Shared and Distinct Associations With Brain and Behavior in Adolescents.

Link: www.jaacap.org/article/S089....

@kavliatyale.bsky.social

16.10.2025 21:41 β€” πŸ‘ 12    πŸ” 9    πŸ’¬ 0    πŸ“Œ 0

thrilled to share our preprint on false memories in naturalistic recollection!

Distinct paths to false memory revealed in hundreds of narrative recalls

paper: doi.org/10.31234/osf...

w/ phoebehc.bsky.social (co-first) Vy A. Vo @davidpoeppel.bsky.social @toddgureckis.bsky.social

thread below πŸ‘‡

16.10.2025 19:29 β€” πŸ‘ 48    πŸ” 13    πŸ’¬ 2    πŸ“Œ 1
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Dense Phenotyping of Human Brain Network Organization Using Precision fMRI The advent of noninvasive imaging methods like functional magnetic resonance imaging (fMRI) transformed cognitive neuroscience, providing insights into large-scale brain networks and their link to cog...

Why do brain networks vary? Do these differences shape behavior? If every 🧠 is unique, how can we detect common features of brain organization?
@rodbraga.bsky.social and I dig in, in @annualreviews.bsky.social (ahead of print):
go.illinois.edu/Gratton2025-...

#neuroskyence #psychscisky #MedSky
πŸ§΅πŸ‘‡

16.10.2025 15:00 β€” πŸ‘ 80    πŸ” 44    πŸ’¬ 1    πŸ“Œ 3

Couldn’t agree more. It’s easy to blame the β€œother” side for not trusting scientists, but to begin to repair these fractures it’s our responsibility to step up and be leaders and engage with the community

15.10.2025 14:30 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Beautiful example of fMRI-based stratification for precision psychiatry!

www.nature.com/articles/s44...

13.10.2025 16:15 β€” πŸ‘ 8    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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Creative experiences and brain clocks - Nature Communications Creative experiences such as dance, music, drawing, and strategy video games might preserve brain health. The authors show that regular practice or short training in these activities is linked to brains that look younger and work more efficiently.

Go do more creative stuff!

www.nature.com/articles/s41...

10.10.2025 14:40 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Functional connectivity is dominated by aperiodic, rather than oscillatory, coupling Functional connectivity (FC) has attracted significant interest in the identification of specific circuits underlying brain (dys-)function. Classical analyses to estimate FC ( i.e ., filtering electro...

This is a fascinating study dissecting the degree to which functional connectivity in EEG is driven by aperiodic activity instead of oscillations -- how robust are connectivity findings in a frequency band (theta, alpha) when oscillations are not omni-present?

www.jneurosci.org/content/earl...

09.10.2025 16:52 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0
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Great to have @timlawn.bsky.social visiting today and presenting some really interesting findings. Cool stuff.

09.10.2025 14:56 β€” πŸ‘ 7    πŸ” 2    πŸ’¬ 0    πŸ“Œ 1

Well put! Thank’s for the shoutout dr smith

08.10.2025 15:13 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Transdiagnostic connectome-based predictive modeling of many behavioral phenotypes reveals brain network mediators of clinical-cognitive relationships Connectome-based predictive modeling (CPM) applied to functional MRI connectivity data can identify brain networks that vary with behavioral measures across subjects. The prediction strength also prov...

New preprint alert!

We used connectome-based predictive modeling in a transdiagnostic sample to identify brain network correlates of wide array of behavioral measures. We also identify where networks supporting cognition overlap with those linked to diagnostically related clinical symptomatology.

06.10.2025 15:42 β€” πŸ‘ 9    πŸ” 5    πŸ’¬ 0    πŸ“Œ 2

If only these jobs were posted 2-3 years from now… my partner and I would love to apply!

23.09.2025 12:32 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Listening to the Brain’s Hidden Rhythms: How Aperiodic Activity is Changing EEG and Depression… Rates of depression have been rising steadily over the past few decades, affecting more than 280 million people worldwide (World Health…

Theo Kertesz, a brilliant intern here in the B&C lab, wrote a fantastic piece about my PhD research. Read it on Medium! medium.com/p/listening-...

23.07.2025 14:29 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Started a new postdoc at Yale in @brognition.bsky.social Lab with Kia Nobre! Studying adaptive cognition in humans using brain recordingsβ€”both on and in the head. New lab, new city, new chapter!

07.07.2025 03:30 β€” πŸ‘ 9    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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If you’re at OHBM this year, come check out my poster titled β€œBrain networks that mediate clinical-cognitive relationships” on Friday and Saturday at location number 1150

26.06.2025 07:28 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

Excited to get this collaborative paper out from my rotation with @dscheinost.bsky.social

19.03.2025 14:56 β€” πŸ‘ 5    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Had a great time discussing network neuroscience (and skiing) at #whistlerbrain2025! Thanks for organizing @toddc.bsky.social and @anjasamardzija.bsky.social!

02.03.2025 23:07 β€” πŸ‘ 7    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Last week to register! (registration closes Jan 26) #whistlerbrain
Register here: web.cvent.com/event/34b0c2...

21.01.2025 13:35 β€” πŸ‘ 13    πŸ” 4    πŸ’¬ 1    πŸ“Œ 0
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β€œCognitive flexibility as the shifting of brain network flows by flexible neural representations”, a solo paper by yours truly, making the case that brain activity flow shifts are essential to mental flexibility (and quite interesting too!)

Open access: www.sciencedirect.com/science/arti...

03.12.2024 18:12 β€” πŸ‘ 102    πŸ” 26    πŸ’¬ 2    πŸ“Œ 0

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