Sauer Lab

Welcome to the youngSMLMS, a pre-SMLMS event for students, PhDs & PostDocs!
We’ll explore science & career in workshops, talks, roundtables, a panel and with time to network.
--> Thanks to our sponsors, youngSMLMS is free & we cover accommodation for all presenting their work. Thus, register now!

Fully Funded PhD Scholarship in Centrosome Biology at University of Galway on FindAPhD.com PhD Project - Fully Funded PhD Scholarship in Centrosome Biology at University of Galway, listed on FindAPhD.com

Fully Funded PhD Scholarship in Centrosome Biology in the lab of Prof Ciaran Morrison: www.findaphd.com/phds/project...

Amazing, congratulations!

Look what's happening at the French Embassy in Washington DC.

Chemical Solutions to Structural Biology symposium.
Registration and abstract submission now open:

isbuc.ku.dk/chemical-sol...

An excellent review about fluorescence labeling strategies by @beliulab.bsky.social Gerti Beliu and colleagues from Würzburg University - highly recommended reading for everybody interested in fluorescence microscopy!

Functionalized Docetaxel Probes for Refined Visualization of Mitotic Spindles by Expansion Microscopy Visualizing the ultrastructure of mitotic spindles, the macromolecular machines that segregate chromosomes during mitosis, by fluorescence imaging remains challenging. Here we introduce an azido- and ...

🆕 Our new functionalized docetaxel probe enables superior visualization of dense mitotic spindle structures during cell division by expansion microscopy!

▶️ pubs.acs.org/doi/10.1021/...

SAVE THE DATE 👇

#FiNS2025
Frontiers in Neurophotonics Symposium 2025
frontiersneurophotonics.org

#Bordeaux, 6-9 Oct 2025

@iins-bordeaux.bsky.social
@cnrs.bsky.social
@univbordeaux.bsky.social
@neurobordeaux.bsky.social
@cnrsbiologie.bsky.social
@gaellerecher.bsky.social

NIH-supported research saves lives: here are two "poster" human beings to prove it.
Emily Whitehead: cured of her leukemia by CAR-T developed at Penn.
Victoria Gray: major symptoms of her sickle cell disease resolved following CRISPR gene editing - path paved at Boston Childrens, UW, UC Berkeley.

Mode of action of the new microscopy method LLS-TDI-DNA-PAINT. On the top right, the RTX antibody was visualised on a Raij-B cell: it is easy to see how it links the CD20 molecules in the membrane. Bottom right: the hedgehog-shaped appearance of a living Raji B cell after the antibody has bound. The surface protein CD45, which is homogeneously distributed on the cell surface, is also labelled in green. (Image: Arindam Ghosh / University of Würzburg)

Delighted to launch our activities on Bluesky with this great news: Our researchers @sauer-lab.bsky.social show in @science.org, how therapeutic #antibodies interact with B cells – thanks to an innovative method of super-resolution microscopy. Congratulations!
➡️ www.uni-wuerzburg.de/en/news-and-...

🔬 Ever wondered how therapeutic antibodies work?
3D LLS-TDI-DNA-PAINT and live-cell LLS microscopy allow decoding of the molecular interplay of endogenous CD20 on B cells with therapeutic antibodies.

📄 Read more: www.science.org/doi/10.1126/...

Decoding the molecular interplay of CD20 and therapeutic antibodies with fast volumetric nanoscopy Elucidating the interaction between membrane proteins and antibodies requires whole-cell imaging at high spatiotemporal resolution. Lattice light-sheet (LLS) microscopy offers fast volumetric imaging ...

Super happy to see the manuscript of my former PhD student and close friend Arindam Ghosh, @arindam92.bsky.social, and the Markus Sauer lab, @sauer-lab.bsky.social, being pblished in Science: www.science.org/doi/10.1126/...

Well-deserved Luke

Happy to see my MSCA project with @jbneuro.bsky.social lab available on @biorxiv-neursci.bsky.social

We Increased network activity in vivo and used dSTORM to look at the nanoscale organization of inhibitory synapses formed onto the AIS and onto tufts dendrites of L2/3 S1 Cortex!