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zhihuachen.bsky.social

@zhihuachen.bsky.social

29 Followers  |  32 Following  |  107 Posts  |  Joined: 26.09.2023  |  2.4324

Latest posts by zhihuachen.bsky.social on Bluesky

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"SARS-CoV-2 is too well-adapted to humans [hence, insert your favorite conspiracy theory]".

That was never right because, for one, SARS-CoV-2 is a pandemic virus so it necessarily had to be "well-adapted".

Now, a new study shows the same is true for BANAL-236 - a related virus isolated from bats.

10.11.2025 20:08 โ€” ๐Ÿ‘ 85    ๐Ÿ” 31    ๐Ÿ’ฌ 3    ๐Ÿ“Œ 1

An additional detail that I have not seen elsewhere

source: bsky.app/profile/ncco...

09.11.2025 16:28 โ€” ๐Ÿ‘ 24    ๐Ÿ” 8    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Correspondence regarding โ€œGeospatial analysis of open-source intelligence data to early detect laboratory-acquired infections, using the 2019 brucellosis laboratory leak in China as a case studyโ€ - In... Infection -

Two weeks ago, a paper came out, claiming that the 2019 Brucella leak in Lanzhou, China, could have been detected months before it was publicly reported.

Problem: no proof was provided to support this extraordinary claim, as we explain in a letter to the editor.

Details follow โ–ซ๏ธ1/6๐Ÿงต

03.11.2025 20:30 โ€” ๐Ÿ‘ 16    ๐Ÿ” 6    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

โ€œFurin cleavage siteโ€, that is. Just casually, and naturally, sitting there in one of the most evolutionarily active parts of the genome.

Mystery solved.

01.11.2025 18:15 โ€” ๐Ÿ‘ 210    ๐Ÿ” 82    ๐Ÿ’ฌ 12    ๐Ÿ“Œ 4

That was really wild when it happened. ๐Ÿ˜‚

01.11.2025 02:41 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Maybe an even more inside baseball in these documents -- but it's key:

No mention of furin cleavage site in the slides...

which matches a remark made by Peter Daszak in an email to David Morens in May 2021, made public by FOIA โ–ซ๏ธ1/8
#CovidOrigin

www.hsgac.senate.gov/wp-content/u...

31.10.2025 20:50 โ€” ๐Ÿ‘ 28    ๐Ÿ” 8    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 1
6 Sep 2022 Twitter conversation

First-author Valentin  Bruttel: You are just not getting it, or don't want to get it. Obviously there will be a lot of "almost" BsmBI/BsaI sites in every 30kbp genome.
The point is that SARS2 is the only one consistent with synthetic virus ligation protocols/the experiments planned in the WIV Preempt proposal.

Zhihua Chen: Nope. The two nucleotides in Wuhan-Hu-1 (10438, 11654) that you have alleged to be perfectly altered to remove Bsal sites exist naturally in RpYN06. Your theory is bankrupt.

6 Sep 2022 Twitter conversation First-author Valentin Bruttel: You are just not getting it, or don't want to get it. Obviously there will be a lot of "almost" BsmBI/BsaI sites in every 30kbp genome. The point is that SARS2 is the only one consistent with synthetic virus ligation protocols/the experiments planned in the WIV Preempt proposal. Zhihua Chen: Nope. The two nucleotides in Wuhan-Hu-1 (10438, 11654) that you have alleged to be perfectly altered to remove Bsal sites exist naturally in RpYN06. Your theory is bankrupt.

This isn't an isolated case. It's part of a pattern.

The "synthetic fingerprint" hypothesis requires omitting contradictory data such as RpYN06.

Worse, authors knew about this contradictory data a month and a half *before* they even published their preprint.

29.10.2025 07:32 โ€” ๐Ÿ‘ 27    ๐Ÿ” 5    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
22-Oct 2022 headline from The Economist
A new paper claims SARS-CoV-2 bears signs of genetic engineering
But it has yet to be peer reviewed. And others strongly disagree

22-Oct 2022 headline from The Economist A new paper claims SARS-CoV-2 bears signs of genetic engineering But it has yet to be peer reviewed. And others strongly disagree

๐ŸงตRemember the preprint claiming SARS-CoV-2 has a "synthetic fingerprint"?

It said a restriction map was "extremely unlikely to have arisen by random evolution.โ€

I took its claims seriously.

The "synthetic fingerprint" hypothesis collapses. My new preprint explains why.

arxiv.org/abs/2510.23833

29.10.2025 07:32 โ€” ๐Ÿ‘ 172    ๐Ÿ” 83    ๐Ÿ’ฌ 4    ๐Ÿ“Œ 9
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Science Journalist Jon Cohen on Preventing the Next Pandemic | KQED We talk to about overcoming denialism and what scientists around the world are doing to keep the most dangerous pathogens at bay.

I really enjoyed this podcast with @cohenjon.bsky.social where he talks about his recent book and the broader, often strange, world of infectious diseases.

With so many non-science journalists opining on topics they know little about, this is a breath of fresh air!

www.kqed.org/forum/201010...

22.10.2025 22:44 โ€” ๐Ÿ‘ 52    ๐Ÿ” 11    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 1
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On an Arctic archipelago, frozen soil may preserve a hidden history of viruses Scientists are hunting for ancient RNA in Svalbardโ€™s permafrost, hoping to shed light on the evolution of viral diseases

I am fascinated by how viruses evolve - and not just since #SARSCoV2 has shown us at the global stage how consequential virus evolution can be for us.
In my new story in @science.org I got to explore how researchers are probing deeper into the past with old RNA virus genome.
So a ๐Ÿงช threadโ€ฆ

18.10.2025 10:02 โ€” ๐Ÿ‘ 217    ๐Ÿ” 77    ๐Ÿ’ฌ 4    ๐Ÿ“Œ 6

Hereโ€™s an op-ed I wrote arguing to get back to a focus on the relevant facts when it comes to pandemic origins.

I wrote it in response to a debate thatโ€™s played out over the last year in Norwegian media that rarely slows down to check whatโ€™s true and false.

01.10.2025 09:14 โ€” ๐Ÿ‘ 27    ๐Ÿ” 10    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 1

This guy spent his entire life online and the authorities haven't released one detail about his online activities. Now why is that?

14.09.2025 17:13 โ€” ๐Ÿ‘ 1089    ๐Ÿ” 183    ๐Ÿ’ฌ 19    ๐Ÿ“Œ 5

I'm hearing a lot of assertions from public officials that Robinson definitely had a left-wing ideological motivation. However, this is coming from folks who have an agenda of their own. I am keeping an open mind and waiting to see what kind of evidence is presented to support this characterization.

15.09.2025 16:36 โ€” ๐Ÿ‘ 90    ๐Ÿ” 11    ๐Ÿ’ฌ 14    ๐Ÿ“Œ 4

Free speech update...

13.09.2025 16:56 โ€” ๐Ÿ‘ 329    ๐Ÿ” 66    ๐Ÿ’ฌ 8    ๐Ÿ“Œ 2

This nyt article has to be one of the most insane things they've ever published

13.09.2025 07:37 โ€” ๐Ÿ‘ 254    ๐Ÿ” 25    ๐Ÿ’ฌ 3    ๐Ÿ“Œ 0

Striking how many, including the sitting president, perpetuate the lie that Thomas Crooks & Luigi Mangione were violent Leftists, despite clear evidence to the contrary.

Crooks was registered Republican described as "definitely conservative" by classmates; Mangione was a Gray Tribe / SSC centrist.

11.09.2025 17:08 โ€” ๐Ÿ‘ 68    ๐Ÿ” 17    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 1
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zhuanti.ziti88.com

08.09.2025 18:00 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Bottom ็บขsomething ็ผ˜. ็บขๅœŸ็ผ˜๏ผŸ

08.09.2025 17:57 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

@zachhensel.bsky.social and I have a new paper on the origin of SARS-CoV-2! ๐Ÿงช

There are a lot of reviews on the topic already, so we tried to do something different: characterize "lab leak" scenarios, and directly address those on SARS-CoV-2's furin cleavage site.โ–ซ๏ธ1/9

doi.org/10.5802/crbi...

08.09.2025 16:22 โ€” ๐Ÿ‘ 53    ๐Ÿ” 25    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 2
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He doesnโ€™t mention that Zhengli Shiโ€™s group had published RaTG15 earlier, disproving the theory.

He does mention another conspiracy theory that the sequencing data Zhengli Shi published mustโ€™ve been fake, though.

So, again, thereโ€™s no chance Shi can publish anything thatโ€™d disprove lab leak.

06.09.2025 19:00 โ€” ๐Ÿ‘ 3    ๐Ÿ” 1    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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โ€˜Really quite shockingโ€™: Inside the ugly transition at the Pentagon The effort to obstruct the Biden team is unprecedented in modern presidential transitions and will hobble the new administration on key national security matters.

www.politico.com/news/2021/01...

Some reporting of the DOD civilian transition tension at the time.

06.09.2025 18:13 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Our Story The Department of Defense provides the military forces needed to deter war and ensure our nationโ€™s security.

web.archive.org/web/20210120...

That page was first updated to contain the picture in question in the afternoon of Jan 20, 2021 eastern standard time. So the change definitely happened on Bidenโ€™s first day. Wondering what went down at DOD then.

06.09.2025 18:09 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

bsky.app/profile/ryan...

Could it even be Trump 1 gift to Biden?

06.09.2025 16:54 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Wait. We are forgetting ๅญ™ๆ‚Ÿ็ฉบ!

Numerous references to ๅญ™ๆ‚Ÿ็ฉบ as ็Œด็ฒพ in ่ฅฟๆธธ่ฎฐ.

ๅป่ชช็މๅธๆ‹†้–‹่กจ็ซ ๏ผŒ่ฆ‹ๆœ‰ๆฑ‚ๅŠฉไน‹่จ€๏ผŒ็ฌ‘้“๏ผšใ€Œๅต่€้€™ๅ€‹็Œด็ฒพ๏ผŒ่ƒฝๆœ‰ๅคšๅคงๆ‰‹ๆฎต๏ผŒๅฐฑๆ•ขๆ•ต้Žๅ่ฌๅคฉๅ…ต๏ผŸๆŽๅคฉ็Ž‹ๅˆไพ†ๆฑ‚ๅŠฉ๏ผŒๅปๅฐ‡้‚ฃ่ทฏ็ฅžๅ…ตๅŠฉไน‹๏ผŸใ€

Heโ€™s also called a ๆ€ช once though. ๐Ÿ˜‚

้€™ๅ€‹ๆ˜ฏๅคชไน™้›ท่ฒๆ‡‰ๅŒ–ๅฐŠ๏ผŒ้‚ฃๅ€‹ๆ˜ฏ้ฝŠๅคฉๅคง่–็Œฟ็Œดๆ€ชใ€‚

Heโ€™s born of a stone. So not really a ็Œด็ฒพ but a ็Ÿณๅคด็ฒพ that developed as a monkey.

05.09.2025 20:38 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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ๅคชๅนณๅปฃ่จ˜ : ่‰ๆœจๅ : ่ณˆ็ง˜ - Chinese Text Project ่ณˆ็ง˜ - full text database, fully browsable and searchable on-line; discussion and list of publications related to ่ณˆ็ง˜. In English and simplified and traditional Chinese.

I canโ€™t either. // Found 7 ๆ ‘็ฒพ from ctext here. ๐Ÿ˜† ctext.org/taiping-guan...

05.09.2025 18:44 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Itโ€™s always ๆ‰“ๆ€ช in video games so definitely ๆ€ช is the more beat-worthy variety. ๐Ÿ˜†

05.09.2025 17:59 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Comptes Rendus. Biologies: Theories of the origin of SARS-CoV-2 in the light of its continuing evolution

by Florence Dรฉbarre, Zach Hensel
@flodebarre.bsky.social
@zachhensel.bsky.social

bit.ly/3I2X2tJ

05.09.2025 16:04 โ€” ๐Ÿ‘ 13    ๐Ÿ” 5    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 4
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Economic viability of high-performance cycle systems: Energy and cost efficiency insights This study evaluates the economic viability of high-performance cycle systems through a comprehensive analysis of energy and cost efficiency factors iโ€ฆ

www.sciencedirect.com/science/arti...

Another one in ESR!

03.09.2025 14:26 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

This is just amazing!

03.09.2025 14:19 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

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