Kate McCluskey

McCluskey et al. publish in Nature Communications how expression of autism genes is enriched in migratory embryonic gut progenitors causing GI dismotility. www.xenbase.org/xenbase/doNe... #science #devbio #xenopus #frogs

Yes! That would be awesome! Doesn’t look like there’s any overlap with known Hirschsprung’s disease genes, but if you know of any other lists to check out please let me know

Huge thanks to everyone who helped out with this project and especially my wonderful mentor @goodfrognosis.bsky.social !!
Also a big thanks to the editor and reviewers for helpful feedback improving this manuscript !

Autism gene variants disrupt enteric neuron migration and cause gastrointestinal dysmotility - Nature Communications Gastrointestinal distress is common among individuals with autism. Here, authors show that autism gene variants disrupt enteric neuron migration and cause gut dysmotility. They identify a common SSRI ...

Excited to share my paper now published at @naturecomms.bsky.social ! We provide evidence that autism gene variants affect enteric neuron migration and cause gastrointestinal dysmotilty. Check it out ! www.nature.com/articles/s41...

Congrats!!! 🎉🎉🎉

Join us for the fantastic annual @cshlnews.bsky.social #Xenopus cell & developmental Biology course.
Deadline for application is Jan 31st.

meetings.cshl.edu/courses.aspx...

Congratulations to newly PhD'ed
@pieceofkate.bsky.social Dr. McCluskey!! She gave a fantastic thesis seminar to cap it off 👏🎓🐸✨

Many autism-linked proteins influence hair-like cilia on human brain cells The finding may help explain autism’s association with multiple co-occurring conditions that involve cilia defects.

Appreciate this generous write up on our recent preprint!

www.thetransmitter.org/spectrum/hai...

🎉 Congrats to the wonderful and talented @elinakosty.bsky.social !! Check out her exciting new preprint where she shows that autism proteins (chromatin regulators and synaptic proteins ! ) converge to localize on cilia

Plus she'll be at ASCB @ascbiology.bsky.social to talk more about it!

Xenopus is an awesome model for ENS development !

Check out James’ cool new paper! Using cilia in frogs 🐸 to study KANSL1 and translating those findings to humans !