Aryeh Solomon

Very cool! What was your turn around time from submission to publication here? Is there a peer review process?

Filamentous phages (viruses) spontaneously align into liquid crystals that protect the bacteria within from antibiotics, desiccation, and the immune system 🦠🧫🧪🧬
www.cell.com/cell-host-mi...

Discovery of single-stranded DNA in meteorite-derived cultures: evidence of novel genetic elements This study presents the first evidence of single-stranded DNA (ssDNA) sequences identified through shotgun metagenomic analysis of meteorite-derived cultures. These ssDNA sequences, predominantly isol...

Well, this preprint is not about bat shit, but I believe the term "bat shit" should be used as part of a descriptor of this preprint:

www.biorxiv.org/content/10.1...

Simulating 500 million years of evolution with a language model More than three billion years of evolution have produced an image of biology encoded into the space of natural proteins. Here we show that language models trained at scale on evolutionary data can gen...

Whoa! When a large language of life model generates a protein equivalent to ~500 million years of evolution.
@science.org
science.org/doi/10.1126/...

Engineered Mycobacterium tuberculosis triple-kill-switch strain provides controlled tuberculosis infection in animal models - Nature Microbiology Engineered kill-switch-encoding Mycobacterium tuberculosis infects, elicits immune responses and is cleared from immunocompetent and immunocompromised mice, providing a model of controlled tuberculosi...

A BCG kill switch strain protects against Mycobacterium tuberculosis in mice and non-human primates with improved safety and immunogenicity
@naturemicrobiol.bsky.social
@saehrt.bsky.social @joanneflynn19.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...

Glad to share the final version of my graduate work!

1/n Some time ago my colleague, excellent cook, and friend Ivan told me: "Cacio e pepe is the recipe that I screw up more often. Let's make a project studying systematically the physics of that sauce".

Prepare to get cheesy, I'm glad to share the Cacio e paper preprint:

arxiv.org/abs/2501.00536

Super cool! Do you think this extends to other viruses as well?

Anti-herpetic tau preserves neurons via the cGAS-STING-TBK1 pathway in Alzheimer’s disease Hyde et al. found elevated HSV-1 protein expression in Alzheimer’s disease, with phosphorylated tau strongly colocalizing with HSV-1 proteins. They demonstrated that tau phosphorylation responds to HSV-1 via the innate immune cGAS-STING pathway, reducing HSV-1 protein expression and increasing neuronal viability, highlighting a role for tau phosphorylation in innate immunity.

Tau is antiviral!

Our group's latest work reveals a surprising role for tau, long considered to be one of Alzheimer's "bad guys".

@cellpress.bsky.social

www.cell.com/cell-reports...

We did the same, I can safely say the ants put us to shame.

I don’t think a repost is an endorsement per say, just an indication you find it interesting or noteworthy.

We all have our vices

But how many additional dimensions would we need to add before seeing “reality”, short of a complete modelling of the system.

Really interesting! How common were female scribes at the time?