Diego García González

Interested in understanding how new cell types evolve? Consider joining our group for a PhD!

RIP John Gurdon

¡Muy chula tu charla, Carmen!
¡Enhorabuena! 👏👏

Vertebrate Genome Evolution. Annual Symposium of the @louisjeantetfdn.bsky.social Foundation in Geneva. Free access on site and on line. Great speakers for a super interesting topic. #SvantePaabo #HenrikKaessmann organisers 🙏 See you there! @biology-unige.bsky.social @genevunige.bsky.social

👇🏽

I add that earlier and later diagnosed autism are not valid diagnostic terms and what we are looking at is (one) gradient. Also genetics explains only a fraction of the variance, with most studied factors explaining < 10%. We have FAQs in the Supplementary where we address common questions.

CORTICAL EVOLUTION - 15-17th June 2026 - Bilbao Spain
Organizers: Verónica Martínez Cerdeño, Fernando García Moreno, Elena Vecino, and Stephen Noctor
Early registration until 1st May 2026
ventricular.org/corticalevol...
@veronicamartinez.bsky.social @phylobrain.bsky.social

Last days to apply! Cool project, cool cities! :-)

(Please repost! 🙏)

🚨 PhD opportunity!
Join our group at @AchucarroNeuro (Bilbao, Spain) for a 4-year bioinformatics PhD on brain evolution 🧠🧬
Work with scRNA-seq & spatial transcriptomics to uncover how the THALAMUS diversified across amniotes!

📩 Apply: fernando.garcia-moreno@achucarro.org

What a beautiful story, Idoia.
Congratulations!

🦟 Mosquitos invasores

👩‍🔬👨‍🔬 El @ceabcsic.bsky.social y @mosquitoalert.bsky.social presentan el primer mapa municipal de la distribución de tres especies invasoras en España: mosquito tigre, de la fiebre amarilla y del Japón

🔎Más de 1.800 municipios han sido colonizados 

👉 http://tiny.cc/ia5s001

The evolution of hominin bipedalism in two steps - Nature The human pelvis exhibits distinct spatiotemporal ossification patterns and an ilium cartilage growth plate that is shifted perpendicularly compared with those of other mammals and non-human primates—...

1) I am delighted to present this terrific tour de force research conducted by my post-doc Dr. Gayani Senevirathne @gayani.bsky.social and published today in Nature -
www.nature.com/articles/s41...

Congratulations, Aixa! 🎉

Estamos bien jodidos

Lamentamos profundamente el fallecimiento del académico José Manuel García Verdugo, catedrático de la Universitat de Valencia. Referente internacional en Neurocencia y Microscopía Electrónica.
Su última charla en la #raciencias puedes recuperarla aquí: www.youtube.com/live/g7nPBVo...

Incredible diversity of #pollen grains!

Pollen autofluorescence acquired with @zeiss-microscopy.bsky.social #superresolution Airyscan & color-coded for depth

#microscopy #bioimaging #bioart #sciart #botany #plantscience #fluorescencefriday

Inactivation of the PHD3-FOXO3 axis blunts the type I interferon response in microglia and ameliorates Alzheimer’s disease progression PHD3 inhibition slows down the pathology and behavioral decline of an Alzheimer’s disease mouse model.

Really happy to see our work on Alzheimer’s disease (AD) microglia published in @science.org www.science.org/doi/10.1126/.... A great work at IBiS from Manuel Sanchez-Garcia, Nieves Lara-Ureña, Rosana March-Diaz, @alicielena.bsky.social , and all our collaborators.

A graphic for the Marie Skłodowska-Curie Actions (MSCA), showing a historical portrait of Marie Skłodowska-Curie overlaid with an image of four young researchers walking down a hallway. The European Commission logo is in the top left. Text reads: "Marie Skłodowska-Curie Actions – €404.3 million to support postdoctoral researchers”

Choose Science. Choose Europe.

A new Marie Skłodowska-Curie Actions Postdoctoral Fellowships 2025 call is now open.

With a budget of €404.3 million, it will support around 1,650 researchers from Europe and beyond.

Apply by 10 September → europa.eu/!fBTMgF

Amazing differences within the EU.

Via prof. Marco te Brömmelstroet on LinkedIn.
NB: 2019 data.

Sequential and independent probabilistic events regulate differential axon targeting during development in Drosophila melanogaster Nature Neuroscience - The developmental origin of behavioral individuality is unclear. The authors show that a temporal sequence of genetically encoded stochastic mechanisms explains variation in...

Hot off the press:
The excellent Maheva Andriatsilavo and colleagues show how a temporal sequence of stochastic molecular mechanisms allow the emergence of stereotyped individualised neuronal circuits. Just published in Nature Neuroscience:
rdcu.be/ek010

A spatial code governs olfactory receptor choice and aligns sensory maps in the nose and brain Although topographical maps organize many peripheral sensory systems, it remains unclear whether olfactory sensory neurons (OSNs) choose which of the ~1100 odor receptors (ORs) to express based upon t...

Maps are everywhere in the brain...and finally we've discovered one in the nose! Led by @davidhbrann.bsky.social, we uncovered the logic that specifies the positions of each of the 1,000 sensory neuron subtypes in the nose and aligns their projections to the brain.👇👃see more details below👃👇

Why does the forebrain expand dramatically while other neural regions grow less? Our new publication reveals progenitor metabolism critically shapes region-specific brain growth. Thread below. authors.elsevier.com/a/1k-udL7PXu...

El próximo Viernes 9 de Mayo, a las 12:30 hrs. en la Sala Washington Buño del #InstitutoCajal, seminario presencial del Dr. Diego García González, @ibis_sevilla @CSIC, con el título: "How to make a newron".
Organizado por: Dra. Aixa V. Morales

Óscar Marín, neurocientífico: “Están en marcha los primeros trasplantes de neuronas 'viajeras' para tratar el cerebro” El investigador español es pionero en el estudio de trastornos del neurodesarrollo como el autismo, la epilepsia y la esquizofrenia, que considera posibles efectos colaterales de la increíble capacida...

🔴 ENTREVISTA | Óscar Marín, neurocientífico: “Están en marcha los primeros trasplantes de neuronas 'viajeras' para tratar el cerebro” www.eldiario.es/128_bace79?u...

Four images to illustrate some prominent single-gene myths. Top left shows a photograph of a person deftly rolling their tongue into a U-shape. Top right shows a photograph of a person’s ear, highlighting the shape and features of the earlobe and cartilage. Bottom left shows a close-up photograph of a person’s eye, with a vivid blue colouration. Bottom right shows a photograph of a person poised to write with their left hand on the blank white page of a spiral-bound notebook.

Remember when you first learned about genetics at school? All those fascinating examples of human traits that are each apparently determined by just a single gene? Time to check in on some of your favourites to see how they’re doing. 🧬🧵🧪 1/n

I could go on with more examples but instead here’s a message to take home. If you’re curious how your genome helps make you unique, don’t expect neat & tidy answers. Indeed, the richness of this tapestry is one of the reasons why human genetics is such a dynamic & exciting field of science. 11/n 🧬🧪

La ciencia como provocación

La UE debe hacer "un poquito más" que doblar su presupuesto para investigación para abandonar la categoría de "simpática anécdota" a nivel global. De lo contrario, nos vamos por el desagüe.
@eloisadelpino.bsky.social @dianamorantr.bsky.social

www.nature.com/articles/d41...

Two scutoids... a gran one and a yellow one.

Graphical abstract of the paper. We infer Forces from geometry to find that scutoids are necessary to form epithelial tubes.

So... Can be animals without #scutoids?
This a difficult question to answer, you cannot get mutants without scutoids.
So we designed a computational model to demonstrated that it is not possible to form epithelial tubes without apico-basal intercalations.
www.csbj.org/article/S200...