After years in making, I am glad to be able to share our attempt on establishing a framework for combined functional and computational assessment of variant pathogenicity in the sodium leak channel NALCN:
www.biorxiv.org/content/10.1...
@chowhanchua.bsky.social
NHMRC Emerging Leadership Fellow | Lecturer in pharmacology, Sydney Pharmacy School, The University of Sydney ๐ช๐จ๐ฆโ Ion channels: LGICs, VGICs and leak channels. ๐ฌ
After years in making, I am glad to be able to share our attempt on establishing a framework for combined functional and computational assessment of variant pathogenicity in the sodium leak channel NALCN:
www.biorxiv.org/content/10.1...
โItโs the company that matters!โ
This is certainly true for acid-sensing ion channel 1a, whose function is modulated by the presence of monocarboxylate transporter 1
All was made possible by the drive & curiosity of the fantastic @mette-h-poulsen.bsky.social
www.biorxiv.org/cgi/content/...
The 3rd Berlin Single Molecule Biophysics Course will run from 8th to 12th September at the HU-Berlin, Institute of Biology.
Learn about single channels, single molecule TIRF, theory and analysis. Apply by 7th July at bsmbc@icloud.com. Fee waivers and bursaries available.
! Please share widely !
Congrats, Susanna!
20.03.2025 03:56 โ ๐ 0 ๐ 0 ๐ฌ 1 ๐ 0Announcing the 40th Cell Physiology Workshop, 11th-22nd August 2025.
Lectures & practicals on electrophysiological recording techniques, experimental design & statistical analysis.
Application deadline: 14th April 2025.
liverpool.ac.uk/life-course-anโฆ
Please repost ๐๐ฆ๐โก๏ธ #cpw2025 #ionchannels
LA applies soooooo much negative pressure that it skips cell-attached and goes straight into whole-cell. โ๏ธ๐ด๐๏ธ๐ค๐ป๐ฟ
20.02.2025 06:06 โ ๐ 2 ๐ 1 ๐ฌ 0 ๐ 0Grateful for the hands-on learning and supportive environment at #ACAN! ๐๐ฌ Iโm absolutely in love with the spirit of ACAN and hope to carry that forward in how I approach science in the future.
20.02.2025 00:30 โ ๐ 2 ๐ 0 ๐ฌ 0 ๐ 0#ACAN turned 20 this year and will remain in Sydney for the next two years! ๐ If you're interested in expanding your neuroscience toolkit and connecting with an incredible network of researchers, I highly recommend applying. It is an intense but rewarding experience you wonโt forget! #Neuroscience
20.02.2025 00:30 โ ๐ 3 ๐ 0 ๐ฌ 1 ๐ 0Huge thanks to the organisers of #ACAN for putting together such an incredible course! It is clear how much time, effort, and coordination went into making this happen. Organising something of this scale is no small featโthank you for making it such a memorable experience! ๐
20.02.2025 00:30 โ ๐ 2 ๐ 0 ๐ฌ 1 ๐ 0The long days (starting at 9 am and experimenting until midnight) were exhausting, but getting to share the experience with a wonderful cohort of students and demonstrators made it incredibly rewarding. @mitaliano.bsky.social @raphapricci.bsky.social @mrdinatale.bsky.social @sushmithasp.bsky.social
20.02.2025 00:30 โ ๐ 2 ๐ 1 ๐ฌ 1 ๐ 0Patching neurons (and dendrites) for the first time was so much FUN!!! โก It's been a while since I last patched (back in May 2021 during my postdoc at @plesslab.bsky.social), so it was great to revisit these techniques and pick up new skillsโespecially while being (literally) surrounded by experts.
20.02.2025 00:30 โ ๐ 2 ๐ 0 ๐ฌ 1 ๐ 0I had a wonderful time attending @acancourse.bsky.social (ans.org.au/acan)! The intensive three-week #ACAN course covered many different modern neuroscience techniques including electrophysiology, optogenetics, and animal behaviour. ๐ง ๐ฌโก
20.02.2025 00:30 โ ๐ 4 ๐ 0 ๐ฌ 1 ๐ 0So.... Preprints only? Or start a journal with no rules and regulations? Call it The Pless Release. Pless = Painless.
17.12.2024 03:19 โ ๐ 1 ๐ 0 ๐ฌ 0 ๐ 0