Edward Fon

Shout out to our collaborators Nicholas Silver and Joel Watts on the paper!

14.05.2025 21:49 — 👍 0    🔁 0    💬 0    📌 0

α-Synuclein purification significantly impacts seed amplification assay performance and consistency α-Synuclein seed amplification assays are a promising diagnostic tool for synucleinopathies such as Parkinson disease and multiple system atrophy. Standardized conditions are required to ensure a high...

Zaid Al-Azzawi’s paper showing the importance of the alpha-Synuclein purification method on the consistency of the Seed Amplification Assay (SAA) is now online. www.biorxiv.org/cgi/content/...

14.05.2025 21:37 — 👍 3    🔁 1    💬 1    📌 1

Midbrain organoids with an SNCA gene triplication display dopamine-dependent alterations in network activity Human midbrain organoids (hMOs) show promise as a patient-derived model for the study of Parkinson's disease (PD). Yet, much remains unknown about how accurately hMOs recapitulate key features of PD i...

Ghislaine Deyab’s paper showing that midbrain organoids from patients with Parkinson’s disease exhibit hallmarks of network activity abnormalities seen in vivo is now out on biorxiv. www.biorxiv.org/cgi/content/...

24.04.2025 20:26 — 👍 3    🔁 0    💬 0    📌 1

Just got around to closing my X account!

25.02.2025 19:04 — 👍 3    🔁 0    💬 0    📌 0

The Quebec government has awarded $1.6M to three McGill researchers to support projects advancing genomics, imaging, and manufacturing. These initiatives will foster collaborations and deliver significant benefits to Quebec and beyond.

➡️ mcgill.ca/x/wr8

17.12.2024 20:57 — 👍 9    🔁 4    💬 1    📌 0

A person is pictured walking in front of a building with pillars on Harvard University’s campus in Cambridge, Massachusetts. Headline reads: "Colleges Warn Foreign Students to Get to Campus Before Trump Takes Office." Photo credit: Adam Glanzman for The New York Times.

A number of colleges, including Harvard, USC and Cornell, are advising their international students to return to campus before President-elect Donald Trump is inaugurated on Jan. 20. nyti.ms/41qkzft

13.12.2024 01:05 — 👍 579    🔁 169    💬 29    📌 26

Mood in Montreal today.

12.12.2024 01:00 — 👍 14    🔁 1    💬 0    📌 0

Lab-grown brain cells help uncover new targets for Parkinson’s treatments.

🧠 Researchers at The Neuro have uncovered a new link between the immune system and the development of the disease.

➡️ mcgill.ca/x/wDZ

29.11.2024 15:54 — 👍 7    🔁 4    💬 2    📌 0

Great work! Congratulations to Peter McPherson and Team!

30.11.2024 14:10 — 👍 1    🔁 0    💬 0    📌 0

Financement de 1,5 million de dollars pour un projet de science ouverte La plateforme de caractérisation des anticorps YCharOS s’attaque à la « crise de la reproductibilité » dans la recherche Le gouvernement du Québec par l’intermédiaire du CQDM vient d’octroyer une…

Le Gouvernement du Québec, par l’intermédiaire du CQDM, octroya une subvention de 1,5 million pour la plateforme YCharOS. Ce projet dirigé par les neuroscientifiques @peter-mcpherson.bsky.social et Carl Laflamme, valide des réactifs d’anticorps pour les protéines humaines.
https://buff.ly/3OjmpXD

21.11.2024 15:00 — 👍 2    🔁 1    💬 1    📌 0

Félicitations!

28.11.2024 01:53 — 👍 1    🔁 0    💬 0    📌 0

The Parkinson’s disease risk gene cathepsin B promotes fibrillar alpha-synuclein clearance, lysosomal function and glucocerebrosidase activity in dopaminergic neurons

Our new paper on Cathepsin B in Parkinson’s just published rdcu.be/d1sJ2

28.11.2024 01:40 — 👍 3    🔁 0    💬 0    📌 0