Aleyah E. Goins

Injury-induced electrochemical coupling triggers organ growth Organ repair and growth rely on coupling tissue-wide membrane depolarization with intracellular proliferative signaling.

New paper alert!🤩Super proud that our story led by superstar postdocs @liujinghui.bsky.social and @nerlielisa.bsky.social is finally out! We found how electrical signals are key for promoting organ regenerative growth!!! A thread 🧵https://www.science.org/doi/10.1126/sciadv.aec0687

Have you seen Xu et al’s results in @nature.com that mitochondrial transfer from glia to neurons protects against peripheral neuropathy? bit.ly/46hu5D2 Come discuss this article with @IASPpain’s @NeuPsig and moderator Courtney Bannerman on 18 Feb #journalclub #painresearch

Distinct activation thresholds of unmyelinated C-fiber afferents by dorsal root ganglion and peripheral nerve stimulation https://www.biorxiv.org/content/10.64898/2026.02.02.703367v1

A Multiscale Model of Collective Decision-Making in Hybrid Aspen Tree Tissues Describes Bud-Dormancy Break https://www.biorxiv.org/content/10.64898/2026.02.04.703817v1

Fair! ✨ cheers! 😁

Playing devil's advocate.....Academia has always been "stick to the template/format", why does it matter if the template has shifted to LLM-style? I feel like a robot writing the same email over and over sometimes, might as well make an actual robot do it instead? 🤔

Latest preprint from our lab reports that the distinct pH of anterograde (less acidic) and retrograde (more acidic) lysosomal vesicles in the axon depends on assembly of the V1 and V0 domains of the vacuolar H+ ATPase, mediated by the metazoan RAVE complex www.biorxiv.org/content/10.6...

Glutamate indicators with increased sensitivity and tailored deactivation rates - Nature Methods iGluSnFR4f and iGluSnFR4s are the latest generation of genetically encoded glutamate sensors. They are advantageous for detecting rapid dynamics and large population activity, respectively, as demonst...

The new glutamate indicators were announced today in
@natmethods.nature.com.

🔗 www.nature.com/articles/s41...

Pain Featured Image 19 Dec

In this week’s #PAIN Featured Image, Gomez et al. describe how the SARS-CoV-2 nucleocapsid (N) protein enhances pathological pain through NaV1.7 modulation. Learn more at bit.ly/4piitaH

The Charge of a Proton: Understanding One of Nature’s Fundamental Constants The Charge of a Proton: Understanding One of Nature’s Fundamental Constants

A protons charge shapes electric fields in atoms - Learn how to choose the perfect telescope --> https://www.telescopeadvisor.com/how-to-choose-a-telescope.php and Get started with this beginners telescope --> https://amzn.to/3JaxN9u #Astronomy #AmazonAffiliate #NASA #Space

My linocut portrait of Maria Goeppert Mayer on 11” x 14” white Japanese paper shows the nuclear shell model energy states in lime green up the left side. Next to this are the magic numbers rising vertically (sums of available energy states): 2, 8, 20, 28, 50, 82, 126 and associated elements for nuclei with those numbers of protons: He, O, Ca, Ni, Sn, Pb with the final hypothetical element unlabelled, all in dark blue. A 3/4 portrait from the chest up in dark blue is all the right side. Mayer has short hair, and wears a dark blouse with long thin white scarf draped around her neck, untied. Below the magic numbers are increasingly large representations of nuclei with increasing numbers of gold and white nucleons like clumps of balls.

Day 16 #artAdventCalendar the woman who figured out why lead is particularly stable & 2nd woman to win the Nobel Prize for #physics 🧪🐡👩🏼‍🔬🎢 #histsci: German-American theoretical #physicist Maria Goeppert Mayer (1906-‘72). As the series of increasingly large atomic nuclei grows with additional nucleons🧵

How basic neuroscience has paved the path to new drugs A growing list of medications—such as zuranolone for postpartum depression, suzetrigine for pain, and the gepants class of migraine medicines—exist because of insights from basic research.

“Basic neuroscience hasn’t produced new drugs.” 💊

Not true - zuranolone (PPD), suzetrigine (pain), gepants (migraine), and more... were born out of a long arc of studies in the lab.

I wrote a Perspective on why this matters. @thetransmitter.bsky.social

www.thetransmitter.org/drug-develop...

Pancreatic cancer is evasive. Is the nervous system the reason why? A growing body of research suggests tumours rely on proteins and genes that are unique to the nervous system to persist in the body.

This is one of those stories where every interview had me like 🤯🤯🤯.

For @nature.com Outlook, I dove into the surprising field of cancer neuroscience.

Edited by the amazing @scchak.bsky.social

www.nature.com/articles/d41...

#neuroskyence

The study shows how individual fingerprint ridges deform when we touch different textures, revealing how subtle stretching and shifting along the ridge flanks may drive our remarkably fine tactile sensitivity.
buff.ly/4z67Vf1

🧠 We're hiring! 🧠 Are you passionate about neuroscience and education? Join our faculty at UNC Chapel Hill to inspire and teach the next generation of neuroscientists. Apply now: 🔗​​https://unc.peopleadmin.com/postings/308455

#Neuroscience #TeachingJobs #AcademicJobs #HigherEd

Robots don’t just “think”—someone codes their brain. AI doesn’t “learn”—people design its rules. If we want these systems to be just, fair, and brilliant, we need diverse coders shaping the algorithms. #STEMEducation #Robot #Robotics #NoireSTEMinist #STEMForAll #CSEdWeek #CSPowersAI #STEAM

Triad – Three papers that point to a new paradigm By: Milton Cohen, John Quintner, and Asaf Weisman We present a triad of our recent papers that we believe hold a key to breaking the stalemate theoretical position that the science and practice of …

A new blog about our recent three publications on the Nociceptive Apparatus Paradigm

#painresearch #physio #neuroskyence

painlosophy.wordpress.com/2025/12/06/t...

Read yet another review today that ascribes GECIs' larger SNR vs GEVIs to their being evolved earlier (suggesting the GECIs are better optimized). This assumption is understandable but incorrect. GEVIs' photonic response per molecule per AP have been as good as GECIs since ASAP3.

Fantastic thread on voltage vs calcium imaging. Via photon flux change per molecule per action potential, they’re similar.

What makes voltage imaging so much harder, then?
Integration time (EPSPs/APs are short), lim ability to jam GEVIs into membrane, and small size of subthreshold Vm changes.
🧪🧠🤖

PRC’s very own Associate Director, Steve Davidson, PhD, took the spotlight as our Keynote Speaker at the 1st NYC Area Pain Research Meet Up! 🎤✨
Talk Title: Humanizing Pain Neurobiology for Translational Gain.

🚀 NAPS applications open this week!

The North American Pain School (@napainschool.bsky.social) brings together leading experts in #PainResearch for an immersive #SummerSchool training and networking experience in Québec.

📍 Apply Nov 28–Jan 31

👉 northamericanpainschool.com/registration/

I take on average 10,000 stills and a half hour of video every week. Most I'll never think about again. This I'll hold onto until I grow old. 4 hours ago.

Zero edits. No recoloring. No cropping. Nothing. Just straight up reality. 🦑

PhD students and Postdocs: The Night Science Podcast (@nightsciencepod.bsky.social) is producing an episode highlighting young scientists talking about their creative process. DM me if you'd like us to consider you for this, & read below what PhD student Davis Garner will contribute! ⬇️

#BookSky I have not been reading as much as I want lately so big reviews have been on hold. I finished off Haruki Murakami's Dance Dance Dance. Fun to read, it was OK. I tried Hermann Hesse's Steppenwolf. Also, just OK. Maybe it's a sign of growth these literary characters aren't packing a punch. 🤷

Reposting this as a reminder to check back when this book comes out 👍

Pretty exciting to develop simpler, faster ways to target specific neuronal subtypes 🤩 I'm looking forward to seeing this be expanded and integrated in future pain studies ☄️ #PainResearch #Neuroscience #DRG #FACS

🎉 Join the 1st NYC Area Pain Research Meet-Up!
🗓 Fri, Dec 5 | 3–6 PM @nyupainresearch.bsky.social , 433 1st Ave, NY, NY
Don’t miss Dr. Steve Davidson’s keynote: “Humanizing Pain Neurobiology for Translational Gain” — plus great company & treats!
Registration below 👇 💫 #PainResearch

The Maldives just became the first country to ban tobacco for an entire generation. Anyone born on or after Jan 1, 2007 can never buy or use tobacco — residents and tourists included.
www.empr.com/news/maldive....