Borrell Lab

Dejamos atrás el mes más largo del año😅y damos la bienvenida a #febrero con esta imagen de Emily Wilson @glb-lab.bsky.social #SciencePhoto_IN 🔬🧠
#Ciencia @csic.es @dicv.csic.es @umh.es

🎉 Enhorabuena al recién nombrado hoy Dr. Eduardo Fernández Ortuño @edufdzortu.bsky.social por su defensa de #TesisIN y felicitaciones a sus directores de Tesis, el Dr. Víctor Borrell y el Dr. Adrián Cárdenas Castelló @borrell-lab.bsky.social 🎉
@umh.es @csic.es @dicv.csic.es

Dynamic subtype- and context-specific subcellular RNA regulation in growth cones of developing neurons of the cerebral cortex Nature Neuroscience - Distinct neuron subtypes compartmentalize specific functions by differentially localizing and translating specific RNAs. This work identifies dynamic subtype- and...

Dynamic subtype- and context-specific subcellular RNA regulation in growth cones of developing neurons in the cerebral cortex. rdcu.be/eXuwg

Congratulations @idoiaeu.bsky.social , and best of luck!! 👏🏻👏🏻👏🏻

Yes, but the question is on this new model and without changing the initial geometry, which you suggest. For example, maintaining same initial geometry, but changing density of radial anchors locally…

What/how much is necessary to modify one (any/all) of these folds? Local loss/gain of density of radial fiber density?

Just a regular thing at @pasteur.fr cantine.

Today we had the pleasure of hosting Dr. Bassem Hassan @hassanbraindevlab.bsky.social from @institutducerveau.bsky.social at our #SeminarsIN with his talk: “Temporal control of neurogenesis”
A fantastic lecture, thank you! 👏👏
@csic.es @dicv.csic.es @umh.es @borrell-lab.bsky.social

We have the pleasure of welcoming Dr Bassem Hassan @hassanbraindevlab.bsky.social from @institutducerveau.bsky.social tomorrow at #SeminarsIN 🙌
He is a world leader in the study of genetic regulation of brain development.
Don’t miss it!
@borrell-lab.bsky.social @csic.es @dicv.csic.es @umh.es

Reaffirming the value of model organisms in training scientific minds - Nature Cell Biology As biomedical research prioritizes human models and translational promise, classic model organisms are increasingly dismissed. Here we argue that they have a lasting value, both in enabling discovery and in cultivating scientific thinking, by training researchers in systems reasoning, integrative thinking and independent inquiry.

The importance of model organisms for research and training www.nature.com/articles/s41...

Congratulations @debbysilver.bsky.social and team. Super! 👏🏻👏🏻👏🏻 This is a game-changing discovery.

I am thrilled to share our latest story led by the incredibly talented Brooke D’Arcy and Camila Musso. We discover a rich world of local gene expression in radial glia, essential neural and glial precursors, and develop a new method for sub-cellular mRNA manipulation. www.biorxiv.org/content/10.1...

Interested in the mechanisms of neurogenesis, and how they might converge/differ across species, regions, and life epochs? Check this out, wonderful location and great science! Please RT

neuro-unige.ch/news/csf-mee...

Un año más en lo más alto 👏🏻👏🏻👏🏻 Felicidades a mis colegas Carlos, Juan, Angela, Salvador y Félix 👍🏻👍🏻

👏 Congrats to @neuroalc.bsky.social researchers named in Stanford’s ranking of the world’s most cited scientists: Carlos Belmonte, @borrell-lab.bsky.social , @jlerma1.bsky.social , Salvador Martínez, @nietoangela.bsky.social & @neuroviana.bsky.social , outstanding global impact in neuroscience!

📅 Hoy es el Día Mundial de la Investigación en #Cáncer, una jornada para visibilizar la ciencia frente a este conjunto de enfermedades 

🔬 Te contamos algunas de las investigaciones oncológicas del #CSIC para mejorar la salud de las personas

#WorldCancerResearchDay 🧵👇

Congratulation! Denis & team. Excellent work! Bravo 👏🏻👏🏻👏🏻

Cell-extrinsic controls over neocortical neuron fate and diversity Cell-extrinsic cues are key for neocortical cell identity and diversity.

Ever wondered how robust cellular identity is to external perturbations? Here we disrupt cellular environmnent in vivo and in vitro, and find cell population specific sensitivities. Environment sculpts development yes, but not all cells are made of the same wood. www.science.org/doi/10.1126/...

The evolution of hominin bipedalism in two steps - Nature The human pelvis exhibits distinct spatiotemporal ossification patterns and an ilium cartilage growth plate that is shifted perpendicularly compared with those of other mammals and non-human primates—...

1) I am delighted to present this terrific tour de force research conducted by my post-doc Dr. Gayani Senevirathne @gayani.bsky.social and published today in Nature -
www.nature.com/articles/s41...

This therapy builds on research from Carlos Belmonte, @neuroviana.bsky.social and colleagues, who showed how corneal cold receptors drive tear production and identified TRPM8 as a target. Once again showcasing the international nature of scientific progress.

Join us if you want to learn about #microglia!

Sharing our newest study led by the incredibly talented @federicamosti.bsky.social investigating new molecular mechanisms of human brain development. We discover a human-specific enhancer HAR1984 that influences chromatin looping to promote cortical size and folding! www.biorxiv.org/cgi/content/...

My quote of the day

I am patient with stupidity but not with those who are proud of it.

Edith Sitwell

The Confocal Room

#ScienceJobs Great opportunity to cutting edge science with a really great mentor!!

I guess genes have something to do on how big brains are. Genes do determine and change brain folds, as shown by a number of different studies from multiple labs worldwide.

The Anne West lab at Duke is hiring a postdoc to work on nuclear cell biology in neurogenesis. Please help me spread the word! Applications to west@neuro.duke.edu.

📢 We are seeking a Head of the Human Brain Organoid Core Facility as part of our Severo Ochoa Centre of Excellence 2023–2026 program.
This is a prestigious leadership opportunity in advanced neuroscience research! 👇
in.umh-csic.es/es/ofertas/t...
@csic.es @umh.es @sommalliance.bsky.social

ENHORABUENA Rafael 👏🏻👏🏻👏🏻 super orgullosos de ti ❤️