Is the UU specificity for piRNA production also seen in mammalian cells? I am aware of UpA suppression (and CpG suppression) in mRNAs and (retroviruses iirc) so was wondering is the selectivity in mammals different? Or do transposons and retroelements have inherently different sequence constraints?
14.02.2026 06:40 β π 0 π 0 π¬ 1 π 0
Feel like doing a SynBio PhD in Spain? Check this offer, many fellowships available ππ» lifehub.csic.es/synbio-cofund/
06.02.2026 06:27 β π 20 π 21 π¬ 0 π 0
Threadπ
02.01.2026 20:08 β π 0 π 1 π¬ 0 π 0
Hard to know what transmission routes might have been behaviourally available/prevalent in palaeolithic lifestyles. (And I donβt know enough about HPV transmission to know if oral transmission is plausible).
31.12.2025 23:43 β π 1 π 0 π¬ 0 π 0
That said, HPV virion is non-enveloped and itβs genome is chromatinised, so maybe has better durability than the cells it is in, so may remain intact on the surface of the bone as the flesh decays? Though ancient DNA is normally sourced from inside the bone to avoid surface contaminants.
31.12.2025 11:11 β π 2 π 0 π¬ 0 π 0
HPVs can be in any mucosal membranes or skin (depending on the type). So a tooth (common source of ancient DNA) would be a not unreasonable place to find HPV16 sequences, but a femur is a bit more surprising to me.
31.12.2025 11:07 β π 1 π 0 π¬ 2 π 0
Watching Bari Weiss Murder Investigative Journalism at CBS
Notes from someone who's withstood White House demands to stop an explosive storyβand who once even had a 60 Minutes piece spiked
As it happens, I have experience with high-level government demands to stop an explosive, accurate story from running, and I also have experience with 60 Minutes spiking a story I was involved in, so I have thoughts about the travesty at CBS. If you want some journalism anecdotes, here are a lot:
30.12.2025 20:05 β π 2491 π 821 π¬ 51 π 90
Huge congrats to first author, brilliant PhD student Martina Demurtas, who is now on the hunt for postdoc positions in London, she is super talented! Also, this was another great experience with @reviewcommons.org and @biologists.bsky.social @Development!
19.12.2025 12:50 β π 4 π 3 π¬ 1 π 0
Please RT. Post-doc opportunity alert! π₯ closing soon 10th December.. Come join our team (www.thelowlab.org) at Imperial, London, working on the structure and mechanism of bacterial secretion systems.
For more details and to apply please see
www.imperial.ac.uk/jobs/search-...
05.12.2025 17:06 β π 22 π 29 π¬ 1 π 0
I had totally forgotten that you were not in our B5 watching posse! And it was a Babylonathon that we used to get everyone up to speed. Have been doing a re-watch with the kids and they were hooked (but we stalled when one had the temerity to go to university)
04.12.2025 21:18 β π 1 π 0 π¬ 1 π 0
Does this post mean you are now up to 26 profanities?
30.11.2025 08:42 β π 1 π 0 π¬ 0 π 0
A One Day Symposium on Frances Hardinge
Politics, Ethics and the Material World: the InterrogativeΒ Fiction of Frances Hardinge.
Please share: I am delighted to release the programme for the July 11 2026, Symposium on the work of Frances Hardinge, at Kings College, London. We can't manage virtual attendance but we do offer cheap conference proceedings. Tickets at Eventbrite: www.eventbrite.co.uk/e/a-one-day-...
29.11.2025 09:19 β π 38 π 27 π¬ 1 π 3
Ah - so the βthey are recovering fine in our bird sanctuaryβ claim at the end of the article does not correlate with survival in the wild. Makes a lot more sense.
29.11.2025 13:42 β π 1 π 0 π¬ 0 π 0
Only when you read to the bottom of the article do you get to βexcept this virus is not lethal in brazilian parrots, (it is claimed)β.
29.11.2025 11:32 β π 1 π 0 π¬ 1 π 0
Currently 3 - 1 PI, 1 postdoc and one research assistant. Plus a couple of Masters students. Based in the UK.
26.11.2025 22:53 β π 1 π 0 π¬ 0 π 0
π€
23.11.2025 00:39 β π 88 π 15 π¬ 2 π 1
I have no idea why they think a vaccine against EBV glycoproteins will impact MS in people who have already developed it. Iβll be astonished (and delighted) if it is effective. But as a prevention against MS (where mono incidence is a measure of efficacy in a trial) I think this study is important.
22.11.2025 18:35 β π 3 π 0 π¬ 1 π 0
YBDTP β BBSRC Yorkshire Bioscience Doctoral Training Partnership
π§ͺ Training includes:
β’ Cryo-EM + SPA
β’ Protein purification + interaction assays
β’ Computational structural biology (AlphaFold, modelling pipelines)
Open to UK applicants and international candidates.
π° Fully funded (UKRI rate stipend + fees).
π
Deadline: 7 January 2026
21.11.2025 09:34 β π 4 π 2 π¬ 1 π 0
Archaeal cells whose DNA has been stained with a blue dye. Zoomed-in images of mutant cells that display chromosome segregation defects.
High-resolution images of DNA-protein complexes obtained with atomic force microscopy. Upon binding, the protein bridges distant sites, forming loops.
π’ Interested in #chromosomes 𧬠& #archaea thriving at the edge of life? PhD project in York,UK on how archaea pass on their genome to daughter cells.Friendly supervisors: me, @steve-quinn-lab.bsky.social & @georgerheath.bsky.social
www.findaphd.com/phds/project...
π
January 7, 2026
Please RPπthx!
09.11.2025 17:20 β π 37 π 33 π¬ 2 π 0
Babylon 5 Earth Alliance SA-23E Aurora Starfury - UCS Scale
Amongst the younger races in the Babylon 5 universe, one single person fighter stands out for it's combination of simplicity, maneuverability, and lethal effectiveness.
This has prompted me to look up Babylon 5 lego - there is a fan build instructions for a Starfury that looks awesome. Just need time to figure out how to order the specific bricks. Sadly no Ivanova minifig though.
rebrickable.com/mocs/MOC-116...
09.11.2025 11:25 β π 3 π 0 π¬ 0 π 0
I very much enjoyed my time in St Andrews, Scotland as a PhD student. If I was still considered an Early-Career Researcher just starting my own laboratory (in my head, I am!), I would certainly be interested in this fellowship opportunity...
05.11.2025 07:26 β π 2 π 1 π¬ 0 π 0
YouTube video by Marsh Family
"Weird Toys" - parody by the Marsh Family of "Bui-Doi" from Miss Saigon about ICE and US protests
Happy #NoKings day to all our friends in the US!
Here's a parody of "Bui-Doi" (Miss Saigon) about the protests, sung initially from the perspective of ICE 'veterans'. Sorry about the ropey accents. ππΆ
youtu.be/FWCalxycuf4
If you enjoy, you know what to do: www.kickstarter.com/projects/mar...
18.10.2025 18:25 β π 128 π 59 π¬ 7 π 9
We have an exciting PhD opportunity to study ribosome hibernation in archaea using cryo-electron microscopy, tomography, microfluidics, omics, and confocal imaging. @daumlab.bsky.social,
@lsiexeter.bsky.social
Apply via:
www.exeter.ac.uk/study/fundin...
Any questions, IM me.
10.10.2025 10:24 β π 9 π 5 π¬ 0 π 1
This headline π€£π€£π€£
09.10.2025 03:46 β π 4254 π 1244 π¬ 138 π 68
Applications for the Crick PhD programme now open. One studentship available in our lab, starting Autumn 2026. Apply!
02.10.2025 19:48 β π 11 π 4 π¬ 0 π 0
I donβt think he specified unvaccinated children. Or advocated endemicity, but regarded it as inevitably the only realistic end to the pandemic. Which was not wrong (given the number of govts unwilling to take the steps required to suppress it and the prevalence in animals).
02.10.2025 21:09 β π 0 π 0 π¬ 0 π 0
M365 Copilot fails to up productivity in UK government trial
: AI tech shows promise writing emails or summarizing meetings. Don't bother with anything more complex
Two trials will be repeated endlessly despite always producing the same results:
1) Does UBI work? (yes)
2) Does AI improve productivity? (no)
06.09.2025 13:02 β π 6346 π 2659 π¬ 69 π 65
enthusiast of transposable elements, genetic conflicts, small RNAs, Drosophila, and funky germline biology
running a lab at IMBA, Vienna BioCenter
https://www.oeaw.ac.at/imba/research/julius-brennecke
Drosophila genetic conflicts
piRNAs | transposons | genomics
Staff scientist in the Brennecke lab - Vienna
Jeopardy! and Times Crossword Champion (semi-retired)
Viral immunologist PhD, sourdough baker and English civil war re-enactor. Mad Aunty & likes sleeping!
MicrobeTV is an independent podcast network for people who are interested in the life sciences. Our shows are about viruses, bacteria, parasites, evolution, immunology and neuroscience.
microbe.tv/contribute
Official.
Our new LP The World is To Dig lands in April. Pre-order and get preview tracks at TMBGshop.com Multi-night stands in Indi Boston Brooklyn Philly Detroit + Chicago! TMBG.com for tickets.
Psych PhD candidate at Emory
Founder and CEO of @standupforscience.bsky.social
Standupforscience.net substack.com/@sciencefightclub
"Colette is brass knuckles...w/ spikes tipped in poison"
βDelusional broadβ
"Lady Switchblade"
βDitsy socialist liberalβ
Asst. Professor of Immunology at Stanford ITI. Working on B cell biology in autoimmune and neuroimmunological diseases. www.lanzlab.com
Evangelist for the study of evolution in action by everyone.
Pitt Prof | EvolvingSTEM | biofilms | EvMed | genomics entrepreneur (@SeqCoast.bsky.social, @midauthorbio.bsky.social) | ASM President-Elect | exercise addict ~ swim bike run
Enthusiastic about understanding what makes viruses tick and what makes humans sick
Virologist | Assistant Prof at Karolinska Institutet | Formerly, TWINCORE (AG Pietschmann), NYU (tenOever lab) and Oxford (Fodor lab)
https://tinyurl.com/48mzfe8f
Associate Professor and Group Leader @Imperial College London
https://profiles.imperial.ac.uk/t.costa
We study the architecture and function of molecular machines that drive antimicrobial resistance (AMR) dissemination and virulence.
PhD student at the Brennecke and Plaschka labs, Vienna.
Interested in RNA silencing
Climate change, global health security, science diplomacy, and good futures β’ Yale and elsewhere β’ carlsonlab.bio β’ viralemergence.org β’ he/they
Female supporters of @CambridgeUtdFC ππ€ | Associate Member of @TheFSA | Promoting Diversity & Inclusion | Official Partner of @Her-Game-Too | #AmberBelles | #CamUTD | #CamUTDW
TheAmberBelles@cambridgeunited.com
Tech journalist and football bore.
Work: https://www.datacenterdynamics.com/en/profile/matthew-gooding
Occasional Cambridge United hot takes: https://notesfromthehabbin.substack.com/
US technology columnist, Bloomberg Opinion. Based in New York. Previously FT and BBC. Watching Cambridge United from afar. dlee1285@bloomberg.net / Signal: davelee.01 / www.davelee.me
π¬ Assistant Prof, Pathology βͺ@Duke | Director, Clin Micro Lab
π§« Former Clin Micro Fellow βͺ@Memorial Sloan Kettering
π©π»βπ¬ Former Postdoc @broadinstitute.org
π PhD @The Rockefeller University
Focus: Diagnostics, AMR, Structural Biology
I enjoy playing with family, reading science fiction and history, gardening, board games, and jazzercise. I'm a father, husband, Navy veteran, and graduate student studying computer science at George Mason University.
Mastodon: https://scicomm.xyz/@David