Giulio Ruffini's Avatar

Giulio Ruffini

@ruffini.bsky.social

Physicist working on computational neuroscience, brain stimulation and foundational aspects of (meta)physics, swimming and music during spare CPU cycles. Neuroelectrics.com, Starlab.es, BCOM.one

388 Followers  |  236 Following  |  87 Posts  |  Joined: 04.10.2023  |  2.0424

Latest posts by ruffini.bsky.social on Bluesky

Annotated version: oup.silverchair-cdn.com/oup/backfile...

16.02.2026 13:41 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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This is the paper where, after almost 20 years, I started taking my AIT obsessions a bit more seriously. I am happy I did... maybe you have some too... => Don't wast time! : )
academic.oup.com/nc/article/2... PS: the Supplementary Data part is more fun!

16.02.2026 13:41 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Philip, agree on 1... but I think the road for studying consciousness is assuming primordial "experience" and instead focus on "structured experience" - and this connects directly with mathematics. See my talk in the "Platonic Space Symposium" thoughtforms.life/wp-content/u...

16.02.2026 09:25 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Thanks, Johannes!

16.02.2026 09:18 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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An Introduction to Galois Theory (with connections to AIT): zenodo.org/records/1845... ...This note aims to demystify Galois Theory by connecting its foundational definitions to a broader principle of computational and compositional tractability.

15.02.2026 11:19 β€” πŸ‘ 5    πŸ” 0    πŸ’¬ 1    πŸ“Œ 1
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From The Sorcerer's Apprentice to Crystal Nights: Security Implications from Moltbot/Moltbook to Greg Egan's Crystal Nights! zenodo.org/records/1844...

15.02.2026 11:16 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Could life have begun with simpler molecules than we once thought? A new paper in @science.org by @edogia.bsky.social shows that a tiny RNA catalyst can self-replicate itself, suggesting that life may have been easier to emerge than expected. Getting closer. www.biorxiv.org/content/10.1...

14.02.2026 11:52 β€” πŸ‘ 45    πŸ” 18    πŸ’¬ 1    πŸ“Œ 1
The Algorithmic Regulator (final version and graphical resources) The regulator theorem states that, under certain conditions, any optimal controller must embody a model of the system it regulates, grounding the idea that controllers embed, explicitly or implicitly,...

Updated version with graphical materials now available here: zenodo.org/records/1864...

15.02.2026 11:11 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Thanks for spreading the word, Ricard!

15.02.2026 11:10 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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What if we had a Rosetta Stone for brain oscillationsβ€”one framework to translate between models and scales?
In this paper lead by F Castaldo and @ruffini.bsky.social they build a simple, systematic ladder of neural mass models showing how diverse formalisms connect arxiv.org/pdf/2512.10982

12.02.2026 18:32 β€” πŸ‘ 19    πŸ” 5    πŸ’¬ 1    πŸ“Œ 0
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My annotated slides for my talk in the wonderful thoughtforms.life/symposium-on... organized by @drmichaellevin are here: giulioruffini.github.io/assets/slide...

31.12.2025 14:50 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Thanks! That was straight from the paper! Uploaded it, clicked on slides…. That’s it!

19.12.2025 22:38 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Paper: mdpi.com/1099-4300/27...
Related: arxiv.org/abs/2510.10586
More on Algorithmic agents: giulioruffini.github.io

19.12.2025 16:43 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Impressed: #notebooklm created a nice presentation of the Algorithmic Agent and Symmetry paper! github.com/giulioruffin...

19.12.2025 16:43 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 2    πŸ“Œ 0

15/ ... plus, linearization of Wilson-Cowan; Connecting SL with Wilson-Cowan.

15.12.2025 16:26 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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14/ Other goodies: discussion using L-operators (for synapses) and transfer functionals.

15.12.2025 16:26 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Definition: A dataset is said to represent an oscillation when it can be most succinctly Lie-generated from a representation of U1 (plus noise). #ait #kolmogorov

15.12.2025 16:26 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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12/ Bonus material: plenty of good stuff in the Appendix for aficionados, including links with Groups, Topology, and Algorithmic Information Theory (What is an oscillation)? @ERC_Research @neurotwin @Neuroelectrics

15.12.2025 16:26 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

11/ If you use neural mass models (or teach them), I’d love feedback: what translation step is hardest in your workflow?
PDF: arxiv.org/pdf/2512.10982
#computationalneuroscience #neuralmass #EEG #MEG

15.12.2025 16:26 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

10/ Practical cheat-sheet:
β€’ Phase locking/entrainment β†’ phase models
β€’ Spectra/covariances β†’ damped linear resonators
β€’ Limit cycles near Hopf β†’ Stuart–Landau
β€’ Firing-rate E–I loops β†’ Wilson–Cowan
β€’ PSP/synaptic kinetics β†’ NMM1
β€’ First-principles spiking link β†’ NMM2

15.12.2025 16:26 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

9/ NMM2 (next-generation masses): Exact mean-field reductions of QIF networks yield dynamic (r,v) equationsβ€”a *dynamic* transfer function replacing static sigmoids, linking spikes ↔ masses.

15.12.2025 16:26 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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8/ NMM1 (second-order synapses):
PING-like motifs, Jansen–Rit, Wendling, and laminar neural masses become variants of one formalismβ€”
highlighting which parameters control resonance, PSPs, and phase shifts.

15.12.2025 16:26 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

7/ Wilson–Cowan then appears as the same backbone made explicit: an E–I push–pull loop + delayed, nonlinear transfer β†’ Hopf/limit cycles,
with clean recipes for forcing & coupling.

15.12.2025 16:26 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

6/ Interlude: synapses + transfer functionals.
Synaptic filters create delays/phase lags; nonlinear transfer function(al)s map summed input β†’ firing-rate output. We keep forcing/coupling consistent across model β€œdialects” via an operator viewpoint.

15.12.2025 16:26 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

5/ Each rung is treated in 3 regimes:
(i) isolated node,
(ii) forced node (external drive),
(iii) coupled network.
Because that’s how models meet data *and* interventions.

15.12.2025 16:26 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

4/ The undamped harmonic oscillator (phase) and the damped HO (phase and amplitude) are natural starting points. We climb a ladder:
HO β†’ damping/forcing/coupling β†’ driven resonator β†’ nonlinearity β†’ Stuart–Landau (Hopf normal form) β†’ connect to classic firing-rate & synapse-based models.

15.12.2025 16:26 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

3/ Neural mass models power EEG/MEG/fMRI generators, whole-brain simulations, and perturbation/stimulation studiesβ€”but the zoo of formalisms makes model choice & interpretation messy.

15.12.2025 16:26 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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2/ Our starting point is simple:
Oscillations can be seen as a push–pull interaction between two effective degrees of freedom (think E↔I, or quadrature components).
That core motif survives as we add biology.

15.12.2025 16:26 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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1/ 🧠 New in Computational Neuroscience: "Rosetta Stone of Neural Mass Models." An unifying framework connecting harmonic oscillator with Stuart-Landau, Wilson-Cowan, NMM1 & NMM2 (next generation). W. @Castaldo_Fr, R de Palma Aristides, P Clusella & J Garcia-Ojalvo - arxiv.org/abs/2512.109...

15.12.2025 16:26 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
Preview
Neural Encoding through Hierarchical Amplitude Modulation Hierarchical encoding is a structural element of the Free Energy Principle and related information-centric accounts of brain function, but a concrete circuit-level mechanism for it remains elusive. He...

Predictions: (i) intermodulation components in frequency‑tagging, (ii) superficial carriers vs deep envelope readouts, (iii) perturb slow rhythms β†’ envelope variance & PSD slope shifts. www.biorxiv.org/content/10.1... #Neuroscience #EEG #Oscillations
@erc.europa.eu @neuroelectrics.bsky.social

05.11.2025 17:00 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

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