Interesting paper this - sounds like much more to come on the microbiome effects of ibezapolstat - effects look significant vs those of vancomycin.
Will be interesting to see if in any way this accelerates recovery of C diff colitis and prevention of recurrence
#IDSky #ClinMicro #MicroSky
12.06.2025 08:08 — 👍 6 🔁 2 💬 0 📌 0
Plumas y virus: la gripe aviar
Sensible y Resistente · Episode
Are you a healthcare professional interested in #H5N1 and fluent in Spanish? Don’t miss this professional podcast, it’s pure gold: "Sensible y Resistente" #IDsky @listeriacolectiva.bsky.social open.spotify.com/episode/0Gon...
11.06.2025 23:04 — 👍 3 🔁 1 💬 1 📌 0
The MEFIER Score—A Risk Score to Stratify Infective Endocarditis in Patients With Enterococcus faecalis Bacteremia Based on an 11-Year Territory-Wide Cohort
The 2023 Duke–International Society for Cardiovascular Infectious Diseases (ISCVID) guideline included Enterococcus faecalis as a typical infective endocarditis (IE) organism irrespective of the primary source and setting of infection. Universal echocardiogram for E. faecalis bacteremia is resource-intensive. Our aim was to develop a risk score that can be applied at the time of bacteremia.MethodsWe conducted a retrospective cohort study utilizing a territory-wide electronic database and included all inpatients (age ≥18) between 2009 and 2019 who had at least 1 blood culture positive for E. faecalis. A multistep machine learning algorithm was employed to generate the risk score.ResultsA total of 2535 distinct E. faecalis bacteremia episodes were analyzed. The percentage of IE was 3.39% (86/2535). The Machine Learning–derived Enterococcus faecalis Infective Endocarditis Risk (MEFIER) score was developed based on history of valvular heart disease (28 points), history of congenital heart disease (14 points), presence of cardiac implantable electronic device (12 points), age (≥18 to <43 years: 3 points; ≥43 to <65 years: 6 points), male gender (2 points), community onset (11 points), and abnormal levels of hemoglobin (16 points), albumin (3 points), and platelets (1 point). With a threshold of ≥32 indicating high risk for IE, the MEFIER score demonstrated an area under the receiver operating characteristic curve of 0.79 (95% CI, 0.72–0.88) and a negative predictive value of 0.98 (95% CI, 0.97–0.99).ConclusionsThe MEFIER score is a unique tool to stratify IE patients with E. faecalis bacteremia, boasting a negative predictive value of 98%, to guide use of echocardiography in these patients.
The MEFIER score predicts infective endocarditis (IE) risk in 2535 E. faecalis bacteremia cases. IE occurred in 3.39% (86 cases). It has a 98% negative predictive value and AUC of 0.79. 📊❤️
#idsky
11.06.2025 01:30 — 👍 1 🔁 1 💬 0 📌 0
fantastic investigator thread about delving deeper into the BALANCE trial (7 vs 14 day antibiotics for bacteremia) to look for heterogeneity of treatment effect 😁
I was allready a BALANCE trial fanboy… this analysis makes it even more appealing. #EMIMCC
11.04.2025 23:16 — 👍 17 🔁 7 💬 1 📌 0
PHONIC
Surveys you can answer with your voice.
If you speak Australian English, consider completing this anonymous online survey; you will have to answer short questions orally and it takes 5-10 mins. This is a pilot to create an interactive linguistic atlas of the accents of Australian English. survey.phonic.ai/6819e46b357d96…
21.05.2025 00:42 — 👍 3 🔁 3 💬 0 📌 0
Why do all my AI-generated doctor pics come out looking like they stepped out of a telenovela?! 😂 Also, all male 🤦♀️Also highly questionable infection control practices...
13.05.2025 00:16 — 👍 0 🔁 0 💬 0 📌 0
🆕💫The MEFIER Score - A Risk Score to Stratify Infective Endocarditis in Patients with Enterococcus faecalis bacteremia based on an 11-year territory-wide cohort
AUROC of 0.79 (95%CI 0.72-0.88), and a NPV of 0.98 (95%CI 0.97-0.99)
#idsky #IEWiki
academic.oup.com/ofid/advance...
12.05.2025 15:56 — 👍 9 🔁 6 💬 4 📌 0
Fluid-attenuated inversion recovery (FLAIR) MRI showing pathological hyperintensity of the chiasm and anterior visual pathway.
Pegivirus hominis, a common virus that has not been linked to specific diseases, was detected in CSF, serum, and brain tissue from four patients with encephalomyelitis, with evidence of independent replication in the CNS. Read the full correspondence: nej.md/437ZK7H
#MedSky #IDSky #NeuroSky
09.05.2025 13:02 — 👍 19 🔁 9 💬 0 📌 1
‼️Artículo imprescindible para entender lo que está pasando con la #GripeAviar #H5N1 en EEUU.
La punta del iceberg es el precio de los huevos, pero debajo de eso hay un problema sanitario de primer orden que afecta a humanos y animales (va mini hilo).
elmundo.es/ciencia-y-sa...
05.05.2025 09:50 — 👍 7 🔁 4 💬 1 📌 0
Do current influenza rapid tests work for H5 (in humans)? All were able to detect bovine H5N1, with ranging sensitivities.
👉 www.medrxiv.org/content/10.1...
22.04.2025 00:09 — 👍 12 🔁 6 💬 1 📌 0
More cats positive for H5N1 bird flu—recent cases reported in Kansas, Pennsylvania, Iowa, and Illinois. Raw cat food linked to previous infections, but current sources unknown.
H5N1 also spreading among other animals across multiple states, including skunks, foxes, mice, a raccoon, and a bobcat
05.04.2025 09:52 — 👍 52 🔁 29 💬 4 📌 4
#Medsky🧪 #IDsky #immunosky #publichealth This #casereport describes a rare case of recurrent coronary artery spasm triggered by urticaria following #COVID infection, emphasizing the importance of considering #Kounissyndrome in patients w a history of infection or allergies presenting with chest pain
04.04.2025 22:01 — 👍 9 🔁 2 💬 1 📌 1
Off-target beneficial effect of live-attenuated herpes zoster (shingles) vaccine (Zostavax).
#IDSky #vaccination
04.04.2025 04:18 — 👍 3 🔁 2 💬 0 📌 0
interesting sub-study from BALANCE:
shorter duration NOT associated w/ ⬇️ resistance - the damage is often already done after the first couple of doses of abx
likely more impact in limiting (broad spectrum) abx exposure than lopping off the last few days of rx…but shorter is still better
#idsky
26.03.2025 02:04 — 👍 17 🔁 1 💬 1 📌 0
AI Search Has A Citation Problem
We Compared Eight AI Search Engines. They’re All Bad at Citing News.
Tow Center for Digital Journalism study found that "AI" chatbots provided incorrect answers to more than 60 percent of queries, with Musk's Grok 3 responding to 94 percent of the queries incorrectly.
"Premium chatbots provided more confidently incorrect answers than their free counterparts."
11.03.2025 12:40 — 👍 566 🔁 316 💬 23 📌 48
Flyways - Pacific, Central, Mississippi, and Atlantic for birds
H5N1 D1.1 isn't your grandpa's bird flu
Most human cases have been mild, but D1.1 hits harder—linked to:
Severely ill child (BC)
Death (Louisiana)
Hospitalization (CO, from WY)
Dairy herds & a worker (NV)
Wild birds spread D1.1 along their flyways
It's springtime again and birds are taking off 🧵
07.03.2025 11:08 — 👍 32 🔁 18 💬 3 📌 3
Applauding this outspoken commentary from @thelancet.bsky.social, standing strong against the current "attack on the health and medical research community".
#NIH #CDC #MedSky #EpiSky #IDSky #HepSky 🧪
06.02.2025 11:11 — 👍 14 🔁 7 💬 2 📌 0
I ❤️ the series! Latest article 👇🏼
#IDSky
06.02.2025 12:07 — 👍 3 🔁 2 💬 0 📌 0
Site Index
STIs are common. Many are curable - all are preventable.
PLEASE SHARE WIDELY #medsky #IDsky #obgynsky #pedsky
CDC STI treatment guidelines have been taken down. They are archived here 👇
web.archive.org/web/20250202...
05.02.2025 06:24 — 👍 1 🔁 1 💬 0 📌 0
Public health experts resisting harmful policies, fighting disinformation, and defending public health from within.
Not official CDC—but close enough for transmission.
Proudly #AltGov
Tips? signal altCDC.99, email altCDCtips@proton.me or DM
Immunologist interested in T cells, B cells, antibodies, vaccines & global health. #StrepA #malaria Lab Head @MonashImmunol @MonashUni She/Her
https://research.monash.edu/en/persons/danika-hill
MS Biology, MPH, MS Cybersecurity |
Evolutionary Biologist 🪼| SciComm ✍🏻|
Bioinformatician 🖥️🧬| Public Health 🛟|
Notorious Bot Hunter 💀| PNW 🌲|
Git 🖥️: https://github.com/bpwhite
Art 🎨: https://crvscience.com
Coffee ☕: https://buymeacoffee.com/crvscience
Podcast hosted by Brett Mitchell & Phil Russo (AU) and Martin Kiernan (UK). Unsponsored, uninfluenced, unfunded (and some would say unhinged). Available on all hosting sites & website with podcasts grouped by topic - www.infectioncontrolmatters.com
Referents en recerca clínica sobre malalties infeccioses. Protegim el futur.
#lluita #recerca #tractament #cura
Mycoses Study Group Education & Research Consortium champion evidence-based diagnoses, prevention, treatment & management. funguseducationhub.org and msgerc.org
ID and Stewardship Specialist 🦠🧫💊
Based in Hamburg, Germany ⚓️ (for now)
Mom of 2 👦🏼👧🏻
Left my ❤️ in San Francisco 🌁
Medical Entomologist & Clinical Bacteriologist — Martinican 🇲🇶 — I talk about Public Health all the time and will do it at your birthday party.
Epidemiologist with expertise in pandemics, healthcare infection prevention, and emergency management.
See my COVID data viz at https://icemsg.org/
Twitter: @maolesen
ID doc & Antibiotic Steward •
• Clinical trials and #FOAMed believer •
Now on @shorten2trial.bsky.social
#AMSsky #IDSky #AMR
Hospital Virgen del Rocío • Seville, Spain 🇪🇸
Migrant|Clinical academic | ID Micro | Vaccines | Bristol (UK) | President British Infection Association *my views here* Official account @biainfection.bsky.social
#vaccine #equity
#social #justice
💚 There is a better way
Professor of viral immunity at Cambridge Uni, Dept of Pathology. Mainly poxviruses and innate immunity. www.fergusonlab.path.cam.ac.uk
Assistant Professor at Cambridge University, Fellow of Downing College. Health security and infectious disease epidemiology with a focus on early detection of emerging & high-consequence infectious diseases.
IDEA Lab
https://hammercc.github.io
Mainly retired PharmD/writer w/34y exp.Infect Diseases. Portrayal of ID in arts/literature.Passionate abt sci literacy and politics. PersonalAcct, boost means I find your post either fun or thought provoking.
Ophthalmologist. Comedian. Speaker. Jonathan.
Infectious Diseases physician at Austin Health and Mercy Perinatal👩⚕️ 🇦🇺
ID interests: Staph aureus 🧫 | Antibiotic allergy 💊 | Perinatal ID 🦠 | Med Ed 👩🏫
Other interests: 🎶 🎻 🥾 ⛰️ 🌳 🍁 📷
Opinions are my own
Professor, MD PhD. Researching in Sepsis, Pneumonia and Emerging Infections. #IDsky. BIOSEPSIS. SCHOOL OF MEDICINE, UNIVERSITY OF SALAMANCA/IBSAL/CIBERES 🇪🇦🇪🇺
Prof/Director of Infectious Diseases & Immunology @austin_health. UoM Research Fellow @ID_austin @CAAR_Aus @TheDohertyInst @UniMelbMDHS #AMS #AMR #penicillinallergy #drugallergy #TID
Infectious Diseases Physician. Clinician Researcher. Immunocompromised Host ID. Transplant ID.
@pmcc @ncic @wslhd
Music lover, keen photographer and proud girl mum. #MedSky #TxID #WomeninSTEM #IDSky #InfectionPrevention #IDOnc
