Himanshu (He/Him)

The world is a cold, dreary place. There is no joy. To be human is to be miserable.

Wordle 1,675 X/6

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Hey, fellow evolutionary biologists:

If you support trans rights, like, comment, or repost this. I want to show that transphobes like Richard Dawkins are a loud minority that does not represent our community

Saw this on Tumblr. Had to post here!!

Nevermind, I solved it.

Connections
Puzzle #885
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What is this "Connections"? 😭

Oh come on now! I am being forced to select the first row.

⚠️Don't forget! You have FREE alternatives!

🔖Reminder that @niaidnews.bsky.social offers 2000+ scientific and biomedical high-quality icons for free use! Check their full catalog: bioart.niaid.nih.gov

📢And if that’s not enough, you also have SciDraw and Bioicons! Comment if you want the websites.

May the person who designed today's game always find their pillow and beer warm.

Connections
Puzzle #829
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An image of two slides. The first slide reads: “In 1965, Benjamin Rubin of Wyeth Laboratories patented his invention of the bifurcated needle • This adaptation of a sewing needle was able to hold a small drop of vaccine between the two small prongs • This method of vaccination used much less vaccine and was easier to perform” The second slide reads: “Bifurcated needles were patented under United States patent number 3,194,237, July 13, 1965 • But Wyeth Laboratories waived all royalties for needles manufactured under contract with the World Health Organization • It’s estimated that 200 million bifurcated needles were used in the eradication campaign (Fenner et al., 1988)”

Today I introduced smallpox eradication in the vaccines class I’m co-teaching w/ @jackiantonovich.bsky.social
A public health hero I learned about prepping for this class is Benjamin Rubin. He developed the bifurcated needle, & waived all royalties for needles manufactured under contract w/the WHO.

Denmark close to wiping out leading cancer-causing HPV strains after vaccine roll-out A nationwide study suggests infections with human papillomavirus (HPV) types 16 and 18 have been virtually eliminated since vaccination began in 2008 – protecting even unvaccinated women.

I am here to say vaccines are awesome because guess what Denmark is close to completely eliminating the two most dangerous HPV strains (serotype 16 and 18) and with the cervical cancer.I think that is bloody AMAZING!!!!
bit.ly/4pbHxjT

Got a new Pride sticker and some chocolates today.

Is it possible for DNA to lag a little behind if the DpnI digested product was directly loaded onto the gel? I am expecting 5.5 kb bands, these are almost 5.8 if not 6. The plasmids were at 5.5 kb before I digested them.

What an incredible read! Seems weird to read something that was written a millennium ago.

In Early-Phase Pancreatic Cancer Clinical Trial, Investigational mRNA Vaccine Induces Sustained Immune Activity in Small Patient Group Learn how MSK researchers are deploying mRNA vaccines against pancreatic cancer.

I wonder if spreading extremely encouraging experimental results on helping treat pancreatic cancer with *gasp* mRNA vaccines may help people who have villainized them come around. This is a good press release on the study and links to the Nature paper. www.mskcc.org/news/can-mrn...

NIH ban on renewing senior scientists adds to assaults on its in-house research Policy follows firings of tenure-track scientists and suspension of training programs

What a concerning news! :(

www.science.org/content/arti...

Tears and panic as immediate impact of Trump's cuts felt by millions in South Africa — Sky News South Africa is home to one of the world's worst HIV/AIDS epidemics. At least 8.5 million people here are living with HIV - and now their treatment is in doubt thanks to Trump's executive order to fre...

apple.news/ARpLnggnJRYG...

Biologists discovered how people and horses get infected by hendra:
- Deforestation
- Bats starve
- Bats sicken, shed hendra virus
- People and horses get sick

Both are DH5alpha cells, picked two colonies off the plate and such a stark difference in colour.

Opinion | A Week Inside One of Northern Gaza’s Last Hospitals Most of the medical staff at Kamal Adwan Hospital is gone. One of the last doctors working there shares his story.

'We have called upon the world for protection for over 50 days but unfortunately there has been no response. I’m confounded by this world that claims to believe in humanity and democracy but does not respond. Not even the World Health Organization has any protection here.'

Trans athlete study concludes blanket bans in sports are a mistake The lead researcher of a landmark IOC-funded study looking at strength, power and aerobic capacity of trans athletes tells Outsports that sports federations should consider its findings carefully.

Study of trans athletes concludes blanket sports bans are a mistake.

The lead researcher of a landmark IOC-funded study looking at strength, power & aerobic capacity of trans athletes says “sports federations should consider its findings carefully.”

www.outsports.com/2024/4/12/24...

Time to head back to my gels.

Currently on the department retreat and tell me how do I go back to the lab when I know a view like this exists?

Thankyou, that does give a direction.

No, these are several different proteins with a single amino acid mutation. But yes, all lanes are cell lysates.

Stuck in protein expression. The proteins from lane 4 onwards should be 48kDa and yet they fall between 33-43kDa. Initially I thought it must have been some contamination so I did another transformation with fresh plasmid but still the same thing.

Variable effects of transient Wolbachia infections on alphaviruses in Aedes aegypti Author summary In recent years, wild populations of Aedes aegypti mosquitoes in over a dozen countries have been deliberately infected with Wolbachia pipientis (“Wolbachia”); an intracellular bacteriu...

🦟New study out of @vectorgen.bsky.social's lab finds #Wolbachia in Aedes aegypti can both help and hinder virus control, depending on the strain.

This highlights the need for more research to unlock Wolbachia's full potential against mosquito-borne diseases.

journals.plos.org/plosntds/art...

Currently struggling with protein induction and this image came on my timeline on that app we don't talk about.

Graph demonstrating rates of vaccine preventable illness decreasing over time

Vaccination saves lives. Period.