Eric Gross MD, PhD

Wishing all our Stanford students the best of luck on finals week — you’ve got this!

Maldives bans smoking for younger generations Anyone born on or after 1 January 2007 will be banned from using, buying or selling tobacco products in the archipelago.

#TobRegSky #PedSky #MedSky #EpiSky #addictionsci #policysky #polisky #neuroskyence #neurosci #PainResearch #addictionsci 🛟 💊

❤️🇲🇻 Maldives enact tobacco-free generation law. 🇲🇻 ❤️

www.bbc.com/news/article...

Tomorrow is the last day to donate for the FAER academic giving competition! If you have not donated already, please donate to FAER to support the next generation of academic researchers in Anesthesiology.
secure.qgiv.com/event/faer-a...

We’d like to welcome Nay Tha who will be working with us as part of the California TRDRP Smoke Vape Scholars Initiative. Welcome Nay!!!! We look forward to working with you.

Looking forward to the research retreat!

As summer comes to a close, we want to congratulate our lab members on an amazing summer of hard work and discovery. Excited for all the great things to come this fall! 🌟🔬 #Teamwork #Research

Congratulations to Harrison on starting his residency at Saint Peter’s University Hospital! Wishing you all the best on this exciting new chapter.

Congrats to Dr. Didi Goodnough for being awarded her first NIH grant!!!!! Didi’s R03 will look at whether a therapeutic to reduce oxidative stress can improve cognitive recovery. #NIA #Alzheimers

Earning either an MD or a PhD is an impressive accomplishment on its own, but what about those who tackled both? Today, we’re thrilled to spotlight Stanford anesthesiologist Dr. Goodnough and hear her story about the path in the clinical and research fields.

We explored the role of TRPV1 in remote cardioprotection.

When you inhibit TRPV1, you lose endogenous protection that occurs from injury such as an abdominal incision.

Link: bpspubs.onlinelibrary.wiley.com/doi/
@ericgross.bsky.social

New discovery to reduce pain inspired by chickens !?
@ericgross.bsky.social
#opioidcrisis #research

Ever wonder what receptor is responsible for the hot sensation after you eat a hot pepper? It’s a nociceptor called TRPV1

This week, we’re spicing things up and talking about Gross Lab research about TRPV1.

We are a translational lab studying anesthetic pharmacology, pain, and organ injury. Our research is published in Science Translational Medicine, Pain, BJA, JCI, Redox Biology, and Physiological Reviews.

Follow us for updates on our discoveries! #StanfordMedicine
@ericgross.bsky.social

Meet Pedro
#stanfordmed
@ericgross.bsky.social

Alcohol intolerance, also called ALDH2 deficiency, is a genetic condition that makes it hard for some people to break down a chemical from alcohol called acetaldehyde.
⚠️Build up of acetaldehyde could lead to long-term health risks!!!
#ALDH2#AlcoholIntolerance
@ericgross.bsky.social

In ancient China, surgeon Hua Tuo (c. 140–208 AD) used “mafeisan”—herbal extracts + alcohol—to induce unconsciousness for major surgeries. Early anesthesia innovation! 🥼🌿

#AnesthesiaHistory @grosslab.bsky.social
@ericgross.bsky.social

When you drink alcohol, it boosts GABA (a calming brain chemical) and blocks glutamate (which stimulates brain activity). This combination of more calming signals and fewer stimulating signals is why alcohol can temporarily reduce pain.
#Anesthesia
@ericgross.bsky.social

Howard Haggard once asked, “What is alcohol doing in the organism?” 🍸 Though already explored as an anesthetic in the 1930s, no modern drugs come from its class. Our lab studies alcohol metabolism via ALDH2 to find new paths in anesthesia & pain relief.#standfordanesthesia

The FDA fired its tobacco enforcers. Now it wants them back. The agency asked laid-off workers to return after gutting the office that penalizes stores for selling tobacco to minors.

The FDA is asking laid-off employees to temporarily return after mass cuts decimated the agency’s ability to penalize stores that sell cigarettes and vapes to minors.

An eppendorf centrifuge in that specific nicotine-yellow color from the 80s. It's the exact color as the old fridge in your garage that you keep sodas in that your parents replaced in 1997, and which has outlived a half-dozen of its replacements.

"Why don't you buy a new centrifuge"

Because everyone knows that any appliances in that shade of yellow will outlive you and your entire family, look at it

Nitroglycerin-responsive gene switch for the on-demand production of therapeutic proteins

www.nature.com/articles/s41...

Building Blocks Of Life Found On Asteroid Bennu Early analysis of asteroid samples from NASA’s OSIRIS-REx mission show the residue of an icy brine, and a soup of amino acids.

Researchers found 14 of the 20 amino acids essential for life on Earth in samples from the ancient asteroid Bennu.

Dr. Danny Glavin and Dr. Dante Lauretta join us to discuss the samples and what they mean for the search for life beyond Earth.

“ [We're] not telling everyone that they should completely stop drinking and that there's never an occasion at which you can have a drink. What we are doing is asking people to reexamine their practices and behaviors with alcohol.” —Surgeon General Dr. Vivek Murthy

In his final advisory, the @Surgeon_General calls for the warning label on alcohol to include cancer risk.

In today's episode, Dr. Vivek Murthy gives his parting prescriptions for a healthier life.

Listen here 🎧: https://buff.ly/3Mut28J

www.popsci.com/science/is-a...

Genetics is important! Carriers of a variant in the alcohol metabolism pathway known as ALDH2*2 causes an accumulation of acetaldehyde which is a known carcinogen. Risk of cancer is higher for carriers of this variant. #dryjanuary #alcohol #Aldh2

As part of #dryjanuary ,
it is important to know that the metabolite of alcohol, acetaldehyde, is a class one carcinogen. If you are alcohol intolerant, you will accumulate acetaldehyde, that over time can cause DNA damage that can lead to cancer. #alcohol #genetics #Aldh2

Surgeon general calls for alcohol to carry cancer warning Alcohol is the third leading preventable cause of cancer in the United States, Vivek Murthy said. Only Congress has the power to mandate changes to warning labels.

www.washingtonpost.com/health/2025/...
Important article about the health risks of drinking alcohol in the post today! Particularly important for people who flush after they drink alcohol as they cannot break down the carcinogen in alcohol acetaldehyde. #dryjanuary #alcohol

Happy 25th Anniversary to those who remember...

The Emergence of a Novel Synthetic Nicotine Analog 6‐Methyl Nicotine (6‐MN) in Proclaimed Tobacco‐ and Nicotine‐Free Pouches Available in Europe At the beginning of 2024, self-proclaimed tobacco- and nicotine-free pouches became available on the European market. Upon chemical analysis of different samples, it was demonstrated that these pouch....

#TobRegSky #PedSky #MedSky #EpiSky #addictionsci #policysky #polisky #neuroskyence 🧪🛟
After we recently reported on the emergence 6-methyl nicotine oral pouch products in the US, such products were also identified in Europe.
analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/...

JPET is looking for editorial fellows!!!!! Applications are open until Dec 11th 2024 for a Jan 2025 start date. Reach out to me if I can help answer any questions. Excellent opportunity- repost and apply.
www.aspet.org/aspet/news/n...

#pharmacology #Academic #research #PhD #phdchat #postdoc

Giving Tuesday! Please consider backing the Gross lab to crowd-fund this study! We want to understand whether there is any science behind pepcid reducing alcohol flushing. Link to back is here! experiment.com/projects/can...
#Science #alcohol #pharmacy #Christmas2024 #holidayseason #HolidayCheer