Bergeron lab

I probably shouldn’t comment on how amazing and transformative I think this work is, since I’m examining the thesis of its first author in a few weeks. So I’m not going to.

King's spin-out company awarded Innovate UK Biomedical Catalyst funding | King's College London King's College London spin-out company Prosemble, co-founded by Dr Julien Bergeron, has been awarded Innovate UK funding as part of the Biomedical Catalyst to transform cancer care with cutting-edge n...

@kingscollegelondon.bsky.social spin-out company Prosemble, co-founded by @bergeronlab.bsky.social has been awarded @innovateuk.bsky.social funding as part of the Biomedical Catalyst to transform cancer care with cutting-edge nanoparticle and AI technologies. Read more: www.kcl.ac.uk/news/kings-s...

😬

That is very cool.

Pure coincidence 😜

The structure of the Tad pilus alignment complex reveals a periplasmic conduit for pilus extension pubmed.ncbi.nlm.nih.gov/40730569/ #cryoEM

The structure of the Tad pilus alignment complex reveals a periplasmic conduit for pilus extension - Nature Communications The Tad pilus is involved in the formation of antibiotic-resistant biofilms in many bacteria, including the human pathogen Pseudomonas aeruginosa. The authors report the structure of the Tad pilus pro...

The peer-reviewed version of Sash and Iryna’s paper on the Tad pilus is out:

That’s also what I thought initially… then I looked closer…

Hmmmm… there’s a, let’s call it “interesting” new sculpture at the entrance of the @crick.ac.uk . I’m curious to hear what this is meant to illustrate.

Superb work from our lab neighbours!

Scientists target 'molecular machine' in the war against antimicrobial resistance Scientists have studied a new target for antibiotics in the greatest detail yet – in the fight against antibiotic resistance.

In a new study, @bergeronlab.bsky.social have used the world’s most advanced electron microscope to reveal the complete architecture of the bacterial flagellum - a molecular machine essential for bacteria to cause infection, that could also be a target for antibiotics ⬇️ www.kcl.ac.uk/news/scienti...

The structure of the complete extracellular bacterial flagellum reveals the mechanism of flagellin incorporation - Nature Microbiology Cryo-electron microscopy analysis of the extracellular flagellum structure, including the hook–filament junction and filament cap complex, reveals mechanisms of flagellin incorporation into the growin...

#NewResearch

🚨Out now!

Structural analyses of the extracellular flagellum shows mechanism for flagellin incorporation

#MicroSky 🦠

www.nature.com/articles/s41...

Scientists target 'molecular machine' in the war against antimicrobial resistance Scientists have studied a new target for antibiotics in the greatest detail yet – in the fight against antibiotic resistance.

A lovely write-up from Kings about our latest paper, and its role in combating antibiotic resistance:

The structure of the complete extracellular bacterial flagellum reveals the mechanism of flagellin incorporation - Nature Microbiology Cryo-electron microscopy analysis of the extracellular flagellum structure, including the hook–filament junction and filament cap complex, reveals mechanisms of flagellin incorporation into the growin...

The peer-reviewed version of our article on the flagellum filament assembly is out!
A masterpiece from duo extraordinaire Kailin and Rosa, and an incredibly productive collaboration with Marc Erhardt and Morgan Beeby.

When they go low, you go high, said a very wise woman

Just goes to show how pathetic Europe is exactly 💪🏻🧪

(Well done European Commission and ERC)

A family of bacterial actin homologs forms a three-stranded tubular structure pubmed.ncbi.nlm.nih.gov/40073056/ #cryoEM

A family of bacterial actin homologs forms a three-stranded tubular structure | PNAS The cytoskeleton is crucial for cell organization and movement. In Eukaryotes, it largely consists of the protein actin, that forms a double-strand...

Latest paper from the lab: the Cryo-EM structure of BeeR! (Yes we did name the protein. No it’s not a coincidence)

Curvature generation and engineering principles from Shewanella oneidensis multi-flagellin flagellum www.biorxiv.org/content/10.1101/2025.02.07.637127v1 #cryoEM

We are a little behind schedule, but the line up for the Next Great Wall Symposium in Sicily in September is coming together more soon. Get ready for those applications for abstracts!!!
thegreatwall-symposium.org

PhD studentship: Structural and functional characterisation of mycobacterial outer membrane proteins at Newcastle University on FindAPhD.com PhD Project - PhD studentship: Structural and functional characterisation of mycobacterial outer membrane proteins at Newcastle University, listed on FindAPhD.com

First post of the year to mark my return from maternity leave :) Excited to share the first open PhD position in my group.
Deadline end of February.
Please spread the word. www.findaphd.com/phds/projectdetails.aspx?PJID=181239

Thanks!