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PfefferCryoLab

@pfeffercryolab.bsky.social

Cryo-electron microscopy, structural biology of molecular machines, ribosome-associated processes, gamma-tubulin complexes

92 Followers  |  45 Following  |  6 Posts  |  Joined: 12.03.2025  |  1.5979

Latest posts by pfeffercryolab.bsky.social on Bluesky

sophiekopetschke.bsky.social

Great collaboration with the Melnikov Lab @sergeymelnikov.bsky.social and the Hill Lab @chillzaa.bsky.social. Congratulations to all authors, in particular the shared first authors Karla Helena Bueno and Sophie Kopetschke sophiekopetschke.bsky.social.

21.03.2025 08:50 β€” πŸ‘ 6    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Structurally heterogeneous ribosomes cooperate in protein synthesis in bacterial cells - Nature Communications Cells can simultaneously produce structurally dissimilar ribosomes, suggesting functional specialization of distinct ribosome populations. Here, the authors show that distinct ribosomes cooperate rath...

Out just now @naturecomms.bsky.social: using cryo-EM and cryo-electron tomography, we provide evidence that structurally heterogeneous ribosomes can cooperate in protein synthesis in bacterial cells:

www.nature.com/articles/s41...

21.03.2025 08:50 β€” πŸ‘ 40    πŸ” 18    πŸ’¬ 2    πŸ“Œ 1
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Structurally heterogeneous ribosomes cooperate in protein synthesis in bacterial cells - Nature Communications Cells can simultaneously produce structurally dissimilar ribosomes, suggesting functional specialization of distinct ribosome populations. Here, the authors show that distinct ribosomes cooperate rath...

Here we unexpectedly find that the ribosomal protein S20/L26β€”identified at the dawn of ribosome research but later deemed a biochemical artifactβ€”is indeed a genuine component of the large ribosomal subunit. More on this ribosome content variation is here: www.nature.com/articles/s41...

20.03.2025 22:05 β€” πŸ‘ 45    πŸ” 23    πŸ’¬ 1    πŸ“Œ 2

Thanks, Friedrich!

21.03.2025 07:01 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Thanks a lot, Marius!

21.03.2025 07:00 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

A great collaboration with the Schiebel Lab @zmbh.uni-heidelberg.de and the Gruss Lab @unibonn.bsky.social. Congratulations to all authors, in particular the shared first authors Qi Gao, Florian Hofer @florianwhofer.bsky.social, Bram Vermeulen @bram-vermeulen.bsky.social and Sebastian Filbeck!

12.03.2025 13:25 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 2    πŸ“Œ 0
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Structural mechanisms for centrosomal recruitment and organization of the microtubule nucleator Ξ³-TuRC - Nature Communications The Ξ³-TuRC plays a central role for nucleation of microtubules at the centrosome. Here, the authors dissect structural mechanisms for centrosomal recruitment and regulation of the Ξ³-TuRC and identify ...

Online today at @naturecomms.bsky.social and a great opportunity for our first post @bsky.app: in a major team effort, we reveal the structural mechanisms for centrosomal recruitment and organization of the human microtubule nucleator Ξ³-TuRC: www.nature.com/articles/s41...

12.03.2025 13:25 β€” πŸ‘ 14    πŸ” 5    πŸ’¬ 1    πŸ“Œ 1

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