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Daniel Brock

@danielbrock.bsky.social

MD/PhD Student Baylor College of Medicine Genetics and retinal degeneration ๐Ÿงฌ๐Ÿ‘€ I like bikes ๐Ÿšฒ

54 Followers  |  110 Following  |  2 Posts  |  Joined: 27.01.2025  |  1.6204

Latest posts by danielbrock.bsky.social on Bluesky

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In vivo CRISPR screens identify modifiers of CAR T cell function in myeloma - Nature In vivo loss-of-function CRISPR screens were performed to identify genes influencing CAR T cell persistence and function in human multiple myeloma, highlighting CDKN1B as a promising target.

Nature research paper: In vivo CRISPR screens identify modifiers of CAR T cell function in myeloma

go.nature.com/3IeODUh

28.09.2025 12:09 โ€” ๐Ÿ‘ 37    ๐Ÿ” 12    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
This is figure 2, which shows organ age estimates predict future age-related disease.

This is figure 2, which shows organ age estimates predict future age-related disease.

In a large-scale proteomic study of biological aging of 11 organs, the biological ages of the brain and immune system emerged as strong predictors of healthspan and longevity, according to a paper in Nature Medicine. go.nature.com/44nLb1M #medsky ๐Ÿงช

13.07.2025 19:28 โ€” ๐Ÿ‘ 28    ๐Ÿ” 6    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
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Decoding gene networks controlling hypothalamic and prethalamic neuron development Kim et al. map gene regulatory networks of the developing mouse hypothalamus and prethalamus using single-cell multiomics, identifying regulators of regionalization and neurogenesis. They further show...

Our paper on gene regulatory networks controlling hypothalamic and prethalamic development is now out in Cell Reports./1
www.cell.com/cell-reports...

14.06.2025 00:48 โ€” ๐Ÿ‘ 36    ๐Ÿ” 12    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Drop by poster B0008 today to learn about genetic risk factors for retinal detachment! We found that variants in VSX2 were associated with an increased risk of retinal detachment in the UK Biobank.

Shout out to my PIs Ben Frankfort and @ryandhindsa.bsky.social!

@arvoinfo.bsky.social #visionscience

07.05.2025 15:13 โ€” ๐Ÿ‘ 4    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Today at the #JointMeeting2025, Svetlana Mojsov, 2024 #LaskerLaureate, gave an impressive overview of how her research on GLP-1 revolutionized the field of glucose metabolism. Her findings led to development of novel therapeutics for #diabetes and #obesity. ๐Ÿงช @a-p-s-a.bsky.social

26.04.2025 21:16 โ€” ๐Ÿ‘ 38    ๐Ÿ” 12    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Postdoctoral Associate- Human Genetics Postdoctoral Associate- Human Genetics

๐Ÿšจ Weโ€™re hiring postdocs! Join our lab in Houston to study human disease using stem cell models, functional genomics, and big genomic data. Wet & dry lab backgrounds welcome.

Please email me if you're interested (ryan.dhindsa@bcm.edu) or apply directly: jobs.bcm.edu/job/Postdoct...

๐Ÿ“ฉ

09.04.2025 14:48 โ€” ๐Ÿ‘ 3    ๐Ÿ” 5    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Check out this tour de force work from @christ3na.bsky.social in my lab!

Her studies reveal how developmental timing in the retina is controlled like an hourglass. The progenitor:neuron ratio shifts to control signaling levels and trigger photoreceptor development over time. Check it out!!

24.03.2025 22:29 โ€” ๐Ÿ‘ 24    ๐Ÿ” 9    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Congratulations to all the medical students who matched today! We are particularly proud of the 15 MDPhD Students that Matched! We can't wait to see what you do next!! @bcmhouston.bsky.social #Match2025 #MatchBCM #doubledoctor

21.03.2025 18:27 โ€” ๐Ÿ‘ 7    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
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Genome-wide prediction of dominant and recessive neurodevelopmental disorder-associated genes Thousands of neurodevelopmental disorder (NDD)-associated genes remain undiscovered, limiting genetic diagnoses. Here, we employ inheritance-specific machine learning models, incorporating gene expres...

Had a lot of fun teaming up with my younger brother and collaborators @bcmfromthelabs.bsky.social and @astrazeneca.bsky.social on this paper! We trained ML models that predict genes linked to dominant and recessive neurodevelopmental disorders @ajhgnews.bsky.social

www.cell.com/ajhg/abstrac...

26.02.2025 23:00 โ€” ๐Ÿ‘ 7    ๐Ÿ” 4    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Baylor College of Medicine MSTP hosted the south regional APSA @a-p-s-a.bsky.social conference on Friday, February 21. Kudos to the student organizers for a great turnout!

25.02.2025 17:50 โ€” ๐Ÿ‘ 7    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Excited that the APSA South Regional Meeting was a success! ๐ŸŽ‰

Huge thanks to attendees, organizers, Baylor & Texas Children's for hosting, and @a-p-s-a.bsky.social for making it happen!

Interested in hosting next yearโ€™s meeting? DM meโ€”weโ€™ve got resources to share! #APSA #PhysicianScientists

25.02.2025 21:04 โ€” ๐Ÿ‘ 3    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Epigenetics Update - KMT2C/KMT2D-dependent H3K4me1 mediates changes in DNA replication timing and origin activity during a cell fate transition bit.ly/3Q9xlYV

#Epigenetics #HIstoneMethylation
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Discover the Paired-tag breakthrough at epigenome.us

07.02.2025 07:51 โ€” ๐Ÿ‘ 7    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
ISER / BRIGHTFOCUS GLAUCOMA SYMPOSIUM:
CONCEPTS AND BREAKTHROUGHS IN GLAUCOMA
ATLANTA, GEORGIA, USA
OCTOBER 8-11, 2025

ISER / BRIGHTFOCUS GLAUCOMA SYMPOSIUM: CONCEPTS AND BREAKTHROUGHS IN GLAUCOMA ATLANTA, GEORGIA, USA OCTOBER 8-11, 2025

Hello Vision Science Peeps!
Be sure to put the @iser.bsky.social / @brightfocus.bsky.social Concepts and Breakthroughs In Glaucoma Meeting on your schedule. It will be in Atlanta, Georgia, USA from October 8-11, 2025
iserbrightfocusglaucoma.org

06.02.2025 23:24 โ€” ๐Ÿ‘ 14    ๐Ÿ” 9    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 2

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