Andrew Harrison

Thank you, Priya! Hope all is well!!

Thank you!

Thanks, Laura! Hope all is well!

Also thx to @madison-strine.bsky.social, @lozanzi.bsky.social, @rathinamva.bsky.social, and all those who helped contribute to this work (& are not yet on BlueSky)!

Thanks to Jon Bogan at Yale for GLUT4 expertise! Danny Yang for his immense help during revision & my PhD. Thanks to our collaborators, co-authors, reviewers + editors at NI for improving the work, friends&family. Also thx to @takarginov.bsky.social, @kailasanvanaja.bsky.social

A big thank you to mentor at UCONN, Penghua Wang. W/o his guidance + support this wasn't possible. We were in lockstep throughout my PhD & his trust in his students to have autonomy definitely prepared me for my next steps as a scientist.

This work reveals GLUT4 tethers RLRs to the plasma membrane, thus inhibiting signal transduction and antiviral immunity. Akin to other transporters, we now show that GLUT4 can have underappreciated roles in regulating innate immunity independent of solute transport.

UBXN9 governs GLUT4-mediated spatial confinement of RIG-I-like receptors and signaling - Nature Immunology Wang and colleagues show that in skeletal muscle cells and cardiomyocytes, the glucose transporter GLUT4 is a negative regulator of RIG-I-like receptor signaling during viral infection by redistributi...

Hi everyone! New to Bluesky, but happy to share the final chapter of my PhD @uconnhealth.bsky.social out today in Nature Immunology! Here, we uncovered a noncanonical function of the glucose transporter GLUT4 in regulating RLR signaling in muscle and adipocytes
www.nature.com/articles/s41...