Darren Fayne

Bluesky?

The deadline is August 5th, so still time to submit an application

Senior Scientist Medical Chemistry (all genders) Senior Scientist Medical Chemistry (all genders)

Opportunity for medicinal chemist at Bayer (Wuppertal Germany) ref: 850032 #MedChem #SynChem #EUChemJobs #ChemJobs #chemsky 🧪
jobs.bayer.com/job/Wupperta...

Very pleased to say we have an Assistant Professor job opening (tenure track) in the Department of Genetics at Trinity College Dublin! 😀
www.jobs.ac.uk/job/DOA399/a... - deadline is August 19th! Please repost!

Promotional graphic with photos of the 9 panellists.

With the 2024 Nobel prize going to Google DeepMind; other tech players are also entering pharma.

Where will future #DrugDiscovery innovation primarily come from?

A panel of experts discuss the opportunities, pitfalls, and possible collaboration opportunities offered by #AI.

🔗 bit.ly/4maBQ3s

I'm looking forward to welcoming two new colleagues to the School of Chemical Sciences in Dublin City University, as we are recruiting Assistant Professors in Biochemistry/Chemical Biology and Chemistry with AI. Please see the adverts below and help spread the word. www.dcu.ie/chemistry/va...

Postdoctoral postion available with me on Computational Materials Design for Hydrogen Storage as part of the @pecathseu.bsky.social (pecaths.eu).

Further information at euraxess.ec.europa.eu/jobs/360228

Sad end of #compchem era… After 30+ years of service, CCL - computational chemistry list will be closing… 😢 #chemsky

Roche is hiring a small-molecule computer-aided drug design researcher in Basel, Switzerland. Go for it! #rdkit #compchem #chemsky www.linkedin.com/jobs/view/42...

CASP is the main reason the protein structure prediction technology and research field advanced over the last 30 years. And the main reason AI based methods have been accepted and widely applied in biology. So shortsighted of NIH to postpone or even halt funding. John Moult is a scientific hero.

On the responsibilities of intellectuals and the rise of bullshit jobs in universities You may never have considered yourself to be one. Why would you? But if you’re reading this, there is more than a likelihood that you are one. If you’re a

Here it is! It’s a great piece that I sent around and got lots of silent 👀

“A recent enquiry I made to my own university revealed, quite shockingly, that last year the U of Oxford gave £3m of the £15m we spent on travel to the travel agency we had contracted with.”

academic.oup.com/brain/articl...

Scientific Leader, Molecular Design We are seeking a highly motivated individual to join our Molecular Design team in Molecular Modalities Discovery. At GSK, we aim to efficiently accelerate the discovery and development of transformati...

Opportunity in molecular design at GSK (Upper Providence PA USA) ref: 423871 #CADD #CompChem #cheminformatics #ChemJobs #chemsky 🧪
gsk.wd5.myworkdayjobs.com/GSKCareers/j...

has anybody looked into the actual savings universities get by requiring academics to book work travel with one specific agency?

these agencies often provide deep discounts for business-class fares, but bog-standard or overpriced economy fares. so one wonders what's actually saved.....

Now in JCIM: pubs.acs.org/doi/full/10....

Edinburgh supercomputer to get £750mn in UK spending review Funding comes after Labour initially pulled money for the project last July

Long overdue,but this is a huge relief and great news for computational research in the UK!

www.ft.com/content/b1e9...

Dr Valesca Lima

#DCUPresidentAwards Profile: Dr Valesca Lima @valescal.bsky.social is an Assistant Professor of Politics at DCU. Dr Lima researches policymaking and governance with three main areas of interest: citizen participation, housing policy, and social mobilisation. #DCUResearch

don’t worry everyone, #chemsky can be perfect so long as we all get along. first things first, we just need to agree that figures go in the text, not bunched up at the end.

Senior Computational Chemist/Molecular Modeller Job Description We seek a highly motivated and experienced Computational Chemist to join our Computational Drug Design group in Oxford. The successful candidate will play a central role in driving dru...

Opportunity for computational chemist at Vertex (Oxford UK) ref: REQ-24796 | closing: 31-May-2025 #CADD #CompChem #cheminformatics #UKChemJobs #ChemJobs #chemsky 🧪
vrtx.wd501.myworkdayjobs.com/Vertex_Caree...

a cartoon of spongebob giving a thumbs up with the word done underneath him ALT: a cartoon of spongebob giving a thumbs up with the word done underneath him

A few years ago Instructional Tech folks at my university dumped email "work tickets" and just added a Zoom link to their webpage. You click, you're in a Zoom with all the experts on duty, you explain your problem, they fix it right then, you go on with your day. I love it. #academicchatter

First DREAM Target 2035 Drug Discovery Challenge 'First DREAM Target 2035 Drug Discovery Challenge' (Synapse ID: syn65660836) is a project on Synapse. Synapse is a platform for supporting scientific collaborations centered around shared biomedic...

@thesgc.bsky.social is generating large/open screening data and inviting data scientists to train their ML models via DREAM challenges:
1- train your model on DEL data
2- retrospectively predict 138 ASMS true positives
3- predict new hits. We will test them and publish together.
bit.ly/3YXVKoT

Application Scientist (Comp. Chemist) Inductive Bio is at the forefront of AI-powered small molecule optimization, helping biopharma partners accelerate drug design with cutting-edge predictive models. Now, we’re looking for an experience...

Opportunity for application-based computational chemist at Inductive Bio (USA hybrid: New York City, San Francisco, Boston) #CompChem #cheminformatics #ChemJobs #chemsky 🧪
jobs.ashbyhq.com/inductive-bi...

"WE'VE ARRANGED A society based on science and technology, in which nobody understands anything about science technology. And this combustible mixture of ignorance and power, sooner or later, is going to blow up in our faces. Who is running the science and technology in a democracy if the people don't know anything about it?" "Science is more than a body of knowledge, it's a way of thinking. A way of skeptically interrogating the universe with a fine understanding of human fallibility. If we are not able to ask skeptical questions, to interrogate those who tell us that something is true, to be skeptical of those in authority, then we're up for grabs for the next charlatan, political or religious, who comes ambling along."

I think a lot about what Carl Sagan said in one of his final interviews.

Every now again it’s useful to repeat advice about accessing papers that are behind a paywall that excludes you. Email the author. My estimate is that 90% of academics are so thrilled that a living, breathing, possibly even reading, person shows interest that they will swiftly send you a copy.

RFK Jr: "Everyone should do their own research."

NIH: "No, not you, scientists."

I could be wrong about this but I really think most Americans do not want to be forced to “do their own research” about food & drug & product safety and would rather that the government agencies that have been sorting that all out for them for decades not be obliterated in the name of “efficiency.”

"80% of projects funded by the European Research Council have led to scientific breakthroughs or major advances."

Report on the EU's current R&I funding programme - which is already half way through its term.

Full descroption and report 👉 europa.eu/!WHpGGg

Liverpool win record-equalling 20th league title with rout of Tottenham * Slot claims Premier League in first season as head coach * 5-1 win over Tottenham seals title with four games left Liverpool have won a record-equalling 20th league title in a stunning debut season for Arne Slot after beating Tottenham 5-1 at Anfield. The 46-year-old, who took on the seemingly unenviable task of succeeding Jürgen Klopp last summer, becomes the first man in Liverpool’s illustrious history to win the championship in his debut season with the club. Anfield was ready to celebrate at kick-off, but there was an early setback when Dominic Solanke unexpectedly headed Spurs in front after 12 minutes. Liverpool hit back quickly, Luis Díaz’s equaliser awarded after a VAR review, before Alexis Mac Allister smashed home in the 23rd minute to put the hosts in front. Cody Gakpo struck from a corner before half-time to leave the outcome all but guaranteed. Continue reading...

Liverpool win record-equalling 20th league title with rout of Tottenham

This is true. I find the dimethyl sulfide report intriguing, but it’s a big universe out there with a lot of chemistry going on in it. We just don’t know enough to say.

Entropy, Enthalpy, and Hydrophobicity

Down into the details of how compounds and binding sites interact: