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@sivanleuven.bsky.social

Consultant rheumatologist at the Radboudumc with a special interest in cardio-rheumatology and Systemic Lupus Erythematosus

15 Followers  |  17 Following  |  11 Posts  |  Joined: 20.05.2025  |  1.5488

Latest posts by sivanleuven.bsky.social on Bluesky

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Atherosclerotic cardiovascular disease in systemic lupus erythematosus: from preclinical lupus to atherosclerotic plaque erosion Abstract. Patients with systemic lupus erythematosus (SLE) have increased risk of developing atherosclerotic cardiovascular disease (ASCVD). This excessive

In our latest publication we highlight #atherosclerosis is already enhanced before the actual SLE diagnosis (diagnostic delay). Moreover #cardiovascular disease in #lupus is associated with an adverse outcome (including recurrent events and mortality). #cardiorheum

academic.oup.com/rheumap/arti...

29.07.2025 11:29 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Hydroxychloroquine Retinal Toxicity | NEJM A 71-year-old woman with systemic lupus erythematosus presented to the ophthalmology clinic for an annual screening examination for hydroxychloroquine-related toxic effects. She reported no vision ...

In addition to hydroxychloroquine dose and duration of use, increasing age, female sex and kidney disease are associated with a higher risk of hydroxychloroquine retinopathy in #lupus patients.

www.nejm.org/doi/full/10....

28.07.2025 08:44 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

The median time from onset of #lupus symptoms or disease signs to a formal SLE diagnosis is an estimated 9 to 78 months! Such major diagnostic delay frequently leads to irreversible organ damage. A unified definition of diagnostic delay and identifying barriers are crucial.

27.07.2025 20:09 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
Dr. Glaucomflecken Explains: Obinutuzumab in Lupus Nephritis (REGENCY)
YouTube video by NEJM Group Dr. Glaucomflecken Explains: Obinutuzumab in Lupus Nephritis (REGENCY)

#lupus When lupus nephritis hits, but so does @glaucomflecken.bsky.social latest reel 😁

'Call the code Lupus' βš‘πŸ”΅
youtu.be/HMkZIpnNbr4?...

05.07.2025 14:19 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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#Pericarditis has a high recurrence rate in #Lupus (20%), especially in younger patients (<40yrs). Use of prednisone >20mg is associated with a high recurrence rate, in a dose-dependent matter. Yet another reason to limit GC exposure. #EULAR2025 #CardioRheum

13.06.2025 12:17 β€” πŸ‘ 5    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Magnificent session on the rigorous process to formulate recommendations for challenging manifestations in #Lupus at #EULAR25. #rheumatology #rheumsky

13.06.2025 11:57 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Very excited to discuss #atherosclerosis and #cardiovascular disease in #Rheumatology at #EULAR2025. Patients with #Lupus and #rheumatoidarthritis may be prone to develop plaque erosion. #CardioRheum #Rheumsky

12.06.2025 15:16 β€” πŸ‘ 7    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Very interesting Hot topics in cardio-rheumatology session at #EULAR2025 with prof. Nurmohamed, Atzeni and Alunno. Risk management guidelines are available, implementation stays behind. Discussed strategies to improve this. #CardioRheum #Lupus #rheumatoidarthritis

12.06.2025 15:02 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Great first day at #EULAR2025 by @eular.org. Very excited to discuss our data on the perspective of patients and rheumatologists on cardiovascular risk management. #rheumatoidarthritis #Lupus #rheumsky #rheumatology

11.06.2025 16:01 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Full house and really impressive results with CAR-T cell therapy in now 27 patients with refractory #Lupus (92% remission). Hopefully these extraordinary results can be reproduced in a larger trial. #EULAR2025 #Rheumatology #Rheumsky

11.06.2025 12:38 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Judging by the amazing view from the roof of our hotel it looks like a great day to get #EULAR2025 going! #Rheumatology #Rheumsky

11.06.2025 05:54 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Atherosclerotic Plaque Progression and Incident Cardiovascular Events in a 10‐Year Prospective Study of Patients With Systemic Lupus Erythematosus: The Impact of Persistent Cardiovascular Risk Factor Target Attainment and Sustained DORIS Remission Objective Cardiovascular disease (CVD) is a leading cause of death in individuals with systemic lupus erythematosus (SLE). We assessed atherosclerotic plaque progression and incident cardiovascular ...

Great study in @ACR-journals.bsky.social. Meeting targets of traditional risk factors (e.g. #cholesterol, BP) and remission of #SLE activity significantly attenutate the increased risk of #atherosclerosis in #Lupus during 10 year followup!

acrjournals.onlinelibrary.wiley.com/doi/10.1002/...

02.06.2025 10:11 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

@sivanleuven is following 17 prominent accounts