Joël Mossong

Come join us!

How might AS01 work? It contains MPL (a TLR4 agonist) and QS-21, which activate dendritic cells and trigger IFN-γ responses, factors implicated in reducing amyloid pathology and slowing cognitive decline in prior studies.
An intriguing immunologic pathway for neuro-protection worth exploring.

Nice!

Seasonal forcing and waning immunity drive the sub-annual periodicity of the COVID-19 epidemic Seasonal trends in infectious diseases are shaped by climatic and social factors, with many respiratory viruses peaking in winter. However, the seasonality of COVID-19 remains in dispute, with signifi...

It’s been a few weeks since posting, but delighted to share this updated preprint for anyone interested www.medrxiv.org/content/10.1...

📣Open call! ESCMID is creating a brand-new #Vaccines Subcommittee 💉and is looking for a director. Interested persons can review the call document & apply before 31 Aug! ow.ly/8Zpx50WjyUA

#IDSky #clinmicro #MedSky

📢 Nearly 600 heat-related deaths expected in UK #heatwave

LSHTM & @granthamicl.bsky.social real-time rapid analysis estimates impact of rising UK temperatures as researchers warn risks set to increase @gasparrini.bsky.social

#PublicHeath

👉 www.lshtm.ac.uk/newsevents/n...

❗ Un premier cas autochtone de #chikungunya a été recensé en France hexagonale, dans le Var.

🦟 Démoustication à venir dans la commune de La Crau.

Sans surprise, du fait de la très forte épidémie à La Réunion et des centaines de cas importés déjà recensés en métropole...

ICE Releases Gavin Newsom Beheading Video WASHINGTON—Disseminating grainy footage of the California Democrat meeting his disturbing and bloody end, Immigration and Customs Enforcement released a video Tuesday in which Gov. Gavin Newsom is see...

ICE Releases Gavin Newsom Beheading Video

YouTube video by Snagsmug Archives Best Bits of Series 1 Not the Nine O’clock News Part 1

Our health setup in these 'new' times

I am really laser focused on getting all my adult patients updated on their vaccines. A few vaccine doses I gave out in clinic today:
- pneumococcal vaccine
- Td booster
- Covid booster
- MMR
- HPV
- Hep B vaccines
8/8 acceptances, zero refusals.
OFFER, COUNSEL, VACCINATE

I knew it….

That’s what Trump and Musk are known for: magnanimity and maturity.

Measles Is Now Showing Up in Wastewater Tracking measles through wastewater is giving health officials a new window into where the virus is spreading.

Measles Is Now Showing Up in Wastewater

Measles cases in the US have been rare in recent decades, thanks to a strong childhood vaccination program. But a few cases inevitably pop up each year as travelers bring the virus in from other countries and infect

time.com/7290566/was...
1/2

Explosive mpox outbreak in Sierra Leone overwhelms health systems Rapid transmission through sexual networks raises fears of wider spread in the region

An explosive outbreak of mpox in Sierra Leone is raising fears of wider spread. The country of 9 million has seen more than 3000 cases already.
“We could see very rapid geographic expansion […] if we don’t really try and get things under control quickly,” says @kindrachukjason.bsky.social
🧪 #IDsky

The spread of Mpox in Sierra Leone is unlike anything we have ever seen - and we have been keeping an eye on this bug in the region for >15 years.

Given geographical spread, 50/50 men vs women, this is no "sexual network".

This could be the next one.

clt.npha.gov.sl/outbreak.aspx

A long thread about mpox and the context specific nature of outbreaks prompted by the large outbreak of MPXV Clade IIb happening at the moment in Sierra Leone:

Call for papers! 📢 

We are inviting papers that discuss, explore or evaluate the (potential) use of LLMs in any step of an epidemiological outbreak investigation, for the planned special issue of Epidemiology & Infection: Using large language models in outbreak response 👇

Oh, and unusually long lasting RSV circulation.

Is the condom becoming counterculture? Is the condom going out of style? Mimi Ronson explores how silence, pressure, and trust are shaping unprotected sex at university

www.varsity.co.uk/features/29670

EuroMOMO Bulletin, Week 18, 2025 EuroMOMO pooled estimates show expected levels of mortality This week’s pooled EuroMOMO estimates of all-cause mortality for the…

www.euromomo.eu/bulletins/20...

In Europe this past winter, we had a big season, mainly because alk 3 subtypes H1, H3 and B cocirculating at the same time. Very busy in primary care, but no unusual severity, no unusually high all-cause mortality and interestingly also the first winter with very little Covid.
erviss.org

An oral norovirus vaccine generates mucosal immunity and reduces viral shedding in a phase 2 placebo-controlled challenge study An oral norovirus vaccine stimulates systemic and mucosal immune responses that predict protection against infection in a phase 2 challenge study.

A phase 2b placebo-controlled trial shows the oral norovirus vaccine VXA-G1.1-NN is safe, immunogenic, and effective. It cut norovirus infection risk by 30% and reduced viral shedding in stool and vomit. Published today in Science Translational Medicine.
#IDSky 🧪
www.science.org/doi/10.1126/...

Trump’s Support Surges After He Points Gun At Nation WASHINGTON—In a dramatic reversal of recent polls showing a decline in the president’s approval ratings during his first 100 days in office, new surveys confirmed Tuesday that President Donald Trump’s...

Trump’s Support Surges After He Points Gun At Nation

Les autorités sanitaires retirent les personnes de 65 ans et plus des cibles de la campagne de vaccination contre le chikungunya avec le vaccin IXCHIQ à La Réunion et à Mayotte – Ministère du Travail,... Le ministère chargé de la Santé et de l'Accès aux Soins a été informé le 23 avril par l'Agence nationale de sécurité du médicament (ANSM) de la survenue de deux événements indésirables graves à la…

French health authorities have suspended vaccination in the Réunion outbreak with Chikungunya vaccine (IXCHIQ-live attenuated vaccine) in adults 65+ following reports of severe adverse events among 80+ adults (severe Chik disease)
#IDSky #TropMedSky #VaccineSky

sante.gouv.fr/actualites/p...

Given discussions at I had at #ESCMIDGlobal, it might be useful for new researchers to know how a journal editor screens submissions (obviously this is my approach and so it might differ for others).

Looking Back at a Defunct ID Meeting -- and Ahead to a Thriving One Back in prehistoric times, many ID doctors and microbiologists would gather each fall at a meeting to review the latest antimicrobial clinical trials and promising “bug-drug” studies of novel compound...

Remember ICAAC? Bad name, weirder pronunciation ("ick-kack"), ugly swag, and a classic case study in conference identity crisis.
A look back—and where the big ID trials land now, which is #ESCMID Global, or whatever it's called. #IDSky blogs.jwatch.org/hiv-id-obser...

ESGEM, the ESCMID Study Group on Epidemiological Markers is launching a working group to develop standards for interpreting AMR genotypes. Much like EUCAST guidance for interpreting lab phenotypes as S/I/R, we want to define the AMRrules for interpreting genotypes.

Anyone presenting an abstract at ESCMID Global:

If you've been approached by a journal to publish that abstract (usually for a fee), you can say no thanks. As in 2024, CMI Comms will publish all abstracts #open-access for free

#IDSky #Clinmicro #MicroSky #MedSky
www.cmi-comms.com/article/S295...

Thessaloniki welcomes the biggest European event for clinical virology! Join us!

ESCV2025 important dates:
✅Registrations open: February 3rd 2025
✅Deadline for Early Registration: June 16th 2025
✅Abstract Submission begins: February 3rd 2025
✅Abstract Submission Deadline: May 12th 2025
escv2025.org

NEW 🧵

A quick thread of charts showing how Trump’s economic agenda is going so far:

1) US consumers are reacting very very negatively.

These are the worst ratings for any US government’s economic policy since records began.