The Dementia League

🧠 Sleep Insights: How much do you really need?

Both short (<7 hrs) and long (≥8 hrs) sleep durations increase odds of subjective cognitive decline (SCD). Addressing sleep disparities could be key to mitigating cognitive decline risk, especially in midlife. buff.ly/IFsG1Cw

COPD patients face a 1.74-fold higher risk of cognitive decline, impacting attention, memory, and executive functions, which can worsen daily living and increase mortality. 🧠 buff.ly/s4TBHMY

While both the ketogenic diet and a control diet helped reduce depression symptoms after 6 weeks, the difference was very small and not very meaningful. Does this impact your mood food choices? buff.ly/AUnkMZq

New research suggests Alzheimer’s may start with failing mitochondria — the brain’s energy systems. Could protecting brain energy early change the disease course?
buff.ly/CO9y2Hm

#Alzheimers #BrainHealth #Neuroscience

🚨 RESEARCHER ALERT: New Alzheimer's Disease MRI Staging Proposed

An individualized brain atrophy score (BAS) for disease staging correlates with dementia severity and cerebrospinal fluid (CSF) biomarkers, enhancing precision in AD management and early risk stratification. 📰https://buff.ly/wPtNYMR

🧠 Higher physical activity trajectories are linked to a 25% lower risk of transitioning from no cognitive impairment to mild cognitive impairment and a 13% reduced risk of MCI progressing to dementia. Learn more: buff.ly/yu34i9F

Like this post if you found it interesting & repost!

New research on Alzheimer's disease shows that problems with the brain's immune system play a key role in the disease, not just the usual focus on certain proteins. Targeting immune responses might be a promising way to slow down memory loss and cognitive decline. 🧠 Read Here: buff.ly/DBiBTwB

That’s a great perspective Sheri. Planning is underrated.

A recent study found that 82% of adults over 50 are open to genetic risk testing for dementia risk. People with higher health literacy and more concerns about Alzheimer's were more willing to test, while reliance on doctors made them less so.

Would you? Why or why not?

📰 buff.ly/BWWl0mE

Not feeling sharp? Kidney problems can impact brain health.

New research shows that chronic kidney disease (CKD) affects not just the kidneys but also brain health because toxins build up and harm the brain. A balanced diet can help kideny functions and brain. 🥗 buff.ly/ImfRKFy

New research shows that exercise can help fight Alzheimer's disease by boosting a process called autophagy, which clears out damaged and dying cells. By combining exercise with natural products, we might find even better ways to manage or prevent Alzheimer's. 🧠 Did you walk today? buff.ly/yQbtLaG

A new study shows that agomelatine, a medication already used for depression, may help protect against Alzheimer's disease in both rats and human brain cells. This research highlights how it could slow down the disease's effects, especially in different sexes. 📰 buff.ly/2ghSBR9

In 2023, 16.9% of US adults aged ≥45 reported subjective cognitive decline, with 59.3% expressing worry about it, highlighting the need for early identification and management. 🧠

Do you feel a reduction in feeling sharp? What have you done that helped?

pubmed.ncbi.nlm.nih.gov/41650298/

Take a second looks at this remarkable finding.

Understanding GABA's Role in Alzheimer's Disease: Study found that reduced synaptic inhibition in neurons occurs before cellular death. GABA receptors play a crucial role in maintaining synaptic health and may offer therapeutic targets.
Learn more: pubmed.ncbi.nlm.nih.gov/41651661/

What healthy food do you genuinely enjoy eating?

Ref: MIND Diet Intervention and Longitudinal Changes in Plasma Amyloid‐Beta 42/40 Ratio Levels in Older Adults. Alzheimers Dement. 2025

Past studies have linked strong MIND Diet habits to up to 50% lower Alzheimer’s risk.
Now randomized trial data are starting to show biological signs that support these benefits. Could what you eat today help protect your brain tomorrow? 🥬🍓

👉 When this blood marker drops, it’s linked to more amyloid in the brain and higher Alzheimer’s risk.

🚨 Groundbreaking 3-year study just dropped: This Diet may have STOPPED progression of Alzheimer's

Participants following the MIND Diet (leafy greens, berries, nuts, healthy meats, olive oil) showed stable plasma Aβ42/40 levels — while the usual-diet group had a significant 2.8% decline.

Wow. Learning a ton today!

Eggsactly 🧠

We heard you! 😊

We will stay on Bluesky and tweak our approach to this platform. We genuinely hope that people have been assisted and educated and encouraged by our posts on brain health and dementia prevention information. 🧠

Just found out that Bluesky does NOT throttle posts with links. 🤯

We will definitely be reviewing our currently Bluesky strategy.

Yes, at least on the other platforms we get views…I think all other platforms actually.

Our goal is to be in multiple languages. We currently test post in mandarin and Spanish on X (poor 1st choice because X is outlawed in china lol).

Over the next few months we want to roll out wider language adoption and try to direct people to the main account, which is the one we monitor.

We thought these platforms SEVERELY throttle posts with external links…though we do try to post links to the articles we review…but these are usually pubmed sites, so this would be easy for platforms to know this is science related (so please don’t throttle).

Maybe we’ll have to try. Blog -> Link

Do you think people would follow the link to Facebook or X?

Will look into that. 🙏

Thanks James. Indeed. Very challenging to fulfill our mission with AI based throttling and sharing, and then the different platforms on top of that.

W/ Bluesky we can’t even see how many views our posts got, just the hearts. So if a post has 0 hearts we don’t have any evidence that it was seen.

We have found the Bluesky platform to be limited in terms of sharing detailed information without tediously making threads.

Let us know if you want us to keep posting on Bluesky by hearting this post. Gonna need 20 hearts to keep this going here.