@dvirschirman.bsky.social
@EMBOFellows postdoc in @johan_elf_ lab, @UU_University. Chromosome organization in bacteria. Combining microscopy and large synthetic libraries to study genotype-to-phenotype. alumnus of @TPilpel lab
One of the most exciting works of my career, years in the making. We used high-throughput precision genome editing to test the fitness effects of thousands of natural variants. Our findings challenge the long-held assumption that common variants are inconsequential.
www.biorxiv.org/content/10.1...
Wow! Very impressive work π€―
23.10.2025 07:21 β π 2 π 2 π¬ 1 π 0I tried the previous version on my preprint, and the feedback was pretty impressive and useful π§π¬
15.10.2025 23:08 β π 1 π 1 π¬ 1 π 0
The @scilifelab.se ancient DNA unit is looking for an bioinformatician placed at Uppsala University. This is a great way to be part of diverse #aDNA research projects as a staff scientist with permanent (!!) employment:
www.uu.se/en/about-uu/...
π’ Dear lovers of prokaryotic chromosomes:
Registration for the Biology & Physics of Chromosomes meeting has been extended until 7 August β³.
Join us!
@biophychrom.bsky.social
@danielabarilla.bsky.social
@damelab.bsky.social
@graingerlab.bsky.social
@biochemsoc.bsky.social
#microsky
Poster advertising the Biology and Physics of Prokaryotic Chromosomes conference that will be held in York, 16-19 September 2025.
Just few days left to register for this chromosome biology fΓͺte! π§¬π§¬π§¬
β³π 16 July
www.eventsforce.net/biochemsoc/f...
@vslioy.bsky.social @damelab.bsky.social @graingerlab.bsky.social @biochemsoc.bsky.social @biophychrom.bsky.social
"A missile attack is not going to hold back science, science is held back by itself" π€£
youtube.com/shorts/FMOi-...
I can add my n=2 anecdotal experience.
I suffered a lot from allergies back in Israel, and since moving to Sweden, I'm completely allergy-free π (but every home visit, they come back with a vengeance!).
My partner had no allergies back home, and here she does π€§
This is how you revolutionize science πΊ
#TCTeAC
Woodstock Night Science is trending more than Trump AND Nature! #TCTEAC
11.06.2025 08:20 β π 23 π 8 π¬ 0 π 0π¬
11.06.2025 08:07 β π 0 π 0 π¬ 0 π 0That was me ππ¦
11.06.2025 08:05 β π 1 π 0 π¬ 1 π 0I used Memrise when I started to learn Swedish (they also have Polish). I don't know if they use AI nowadays, but anyway, they rely a lot on short clips of a variety of native speakers.
www.memrise.com
We got today samples of iSpacer from SunJinLab.
www.sunjinlab.com/ispacer-sele...
It seems promising, although might be a bit too thin on the short side of the rectangle.
I'll update once we've tested it properly.
Earnshaw, Goloborodko, Dekker & Mirny labs are excited to present our latest work, "Rules of engagement for condensins and cohesins guide mitotic chromosome formation" - now accepted!!
www.science.org/doi/10.1126/...
A short clip describing the key results:
www.youtube.com/watch?v=pmvO...
There's a lot of joy in doing science and Woodstock Night Science (June 10-13 in Prague) will be a celebration of the science that we know and love. Many exciting talks & innovations that will push the boundaries of what a scientific conference can really do.
woodstock.img.cas.cz Only 40 spots left!
We are using them, and also our neighboring lab.
Johan Elf & Magnus Johansson labs, Uppsala University, Sweden
Fellow bacterial cell biologists, message me if you use @thermofishersci.bsky.social Gene Frames for microscopy!
Thermo are planning to discontinue these in September but have indicated they will look into this further.
If I make list of labs using them Thermo might not kill the product
Please RTπ¬π¦
Good chance you already listen to it, but if not @dancarlin.bsky.social Hardcore History is the best recommendation. Very long series each of them basically an audio book. Wrath of the Khans on the mongol empire would be a great start
03.04.2025 09:29 β π 2 π 0 π¬ 0 π 0
We are looking for a postdoc with microbiology background for #superresolution #singlemolecule #ERC tracking project. Apply by 27.4.2025. π¦ π¬π§«
Pls share!
www.aalto.fi/en/open-posi...
Schematic of probability distribution of the latent period along with single-cell examples of bursts that increase in magnitude as the latent period increases. Full details in the paper.
New on #biorXiv: 'Inferring single-cell heterogeneity of bacteriophage life-history traits from population-scale dynamics'. A theory-experiment collaboration, led by @mariandm.bsky.social + Ran Tahan w/the Lindell group at Technion (and yes, I am excited).
a π§΅
www.biorxiv.org/contenat/10....
1/46 Hey folks, we have a new paper out on the MuLTEE. Strap in and Iβll tell you the story of how this βlittle paper on polyploidyβ turned into the most data rich paper our lab has produced, largely thanks to the leadership and work ethic of @kaitong25.bsky.social.
www.nature.com/articles/s41...
Itβs been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendritic cell sarcoma (IDCS). Iβm reaching out to identify clinicians/patients who have encountered pediatric IDCS or other (non-LCH) dendritic or histiocytic sarcomas cases.
08.02.2025 21:21 β π 1010 π 849 π¬ 83 π 32
A snowflake yeast cluster, with the MitoLoc mitochondrial fluorescent probe. The outer ~4-5 cell layers are aerobic and respiring, the interior is anaerobic.
Hi folks, I'm excited to share a whale of a tale (sorry, bad pun), where we engineer snowflake yeast to express sperm whale myoglobin, and explore how oxygen-binding proteins may have helped overcome anatomical limitations to early multicellularity. π§ͺ #MEvoSky
journals.plos.org/plosbiology/...
This week @science.org Sarfatis, Moffitt et al. from @bostonchildrens.bsky.social @harvardmed.bsky.social @broadinstitute.org
Highly multiplexed spatial transcriptomics in bacteria | Science www.science.org/doi/10.1126/...
#microsky #microbial #microbiology #genomics
#transcriptomic π¦ π§«
If you're interested in chromosome biology (DNA folding, gene regulation, replication, polymer modelling and more) we're organising the below this autumn. It'd be great to see you there. Please share if you can. :-)
21.01.2025 19:49 β π 26 π 29 π¬ 0 π 4
We are excited to announce that the call for the new SciLifeLab PULSE postdoctoral program is now open!
This unique program invites talented researchers to propose individually designed projects see : www.scilifelab.se/research/pul.... The deadline for applications is March 31, 2025.
ΧΧΧΧ‘Χ ΧΧΧ¨Χ ΧΧΧ©Χ¨ΧΧ ΧΧΧ’ΧΧ¨ ΧΧΧΧ ΧΧ§ΧΧͺ ΧΧΧͺΧ¨ ΧΧΧ, ΧΧ’ΧΧ§Χ¨ ΧΧ ΧΧ‘ΧΧ Χ’Χ ΧΧΧ’Χ, ΧΧ Χ¦Χ¨ΧΧ ΧΧ’ΧΧΧ¨ ΧΧΧΧΧ Χ Χ¦'Χ§ ΧΧΧ ΧΧΧ ΧΧ’ΧΧΧ¨ ΧΧͺ ΧΧͺΧ©ΧΧΧ ΧΧΧΧΧΧ Χ.
(ΧΧ©ΧΧͺΧΧͺΧ Χ©ΧΧ ΧΧ¨ΧΧΧ© ΧΧΧ Χ§ΧΧ Χ§Χ©Χ Χ¨ΧΧΧ, ΧΧ ΧΧΧ ΧΧ Χ©Χ’ΧΧ©ΧΧ Χ¦'Χ§ ΧΧΧ ΧΧΧ ΧΧΧΧ)
Χ’ΧΧ¨ΧͺΧ ΧΧͺ ΧΧ ΧΧΧ¨ ΧΧΧ Χ€Χ’ΧΧΧ ΧΧΧ ΧͺΧΧΧΧͺ ΧΧΧΧΧΧ (ΧΧ©ΧΧΧΧ ΧΧ
ΧΧΧΧΧ ΧΧ€ΧΧ ΧΧ§ΧΧ©Χ ΧΧΧ ΧΧΧ‘ΧΧͺ ΧΧ©ΧΧ¨ΧΧͺ).
ΧΧΧ ΧΧ ΧΧ© code share, ΧΧΧΧΧ ΧΧ©ΧΧ¨ΧΧͺ ΧΧΧΧΧ¨ΧΧͺ ΧͺΧ’ΧΧ€Χ.
ΧΧ ΧΧ Χ©ΧΧΧΧΧ ΧΧΧΧΧΧΧͺ, ΧΧΧΧ‘Χ ΧΧΧ©Χ¨ΧΧ, ΧΧ ΧΧ¨ΧΧΧ© ΧΧΧΧΧ§ ΧΧΧ Χ§ΧΧ Χ§Χ©Χ Χ¨ΧΧΧ. Χ’ΧΧΧΧ ΧΧΧΧΧ₯ ΧΧ§ΧΧͺ ΧΧΧ€Χ¨ ΧΧΧΧ ΧΧΧͺΧ¨ ΧΧΧΧ Χ©ΧΧΧ ΧΧ Χ©ΧΧ§Χ ΧΧΧ¨ΧΧΧͺ ΧΧΧ§Χ¨Χ Χ©Χ ΧΧΧΧΧ¨ Χ©Χ ΧΧΧΧ‘Χ ΧΧ¨ΧΧ©ΧΧ Χ.
We are seeking a motivated postdoc to join our lab! Β Our research focuses on live-cell imaging/analysis to reveal how chromatin behaves in living cells and how its behavior contributes to cellular functions.
www.nature.com/articles/s41...
www.science.org/doi/10.1126/...
Interested? Please DM me!
