Halim Loukil

🥳 Our new paper on C2CD3 is out in @plosbiology.org
With the labs of @cellarchlab.com , @chgenoud.bsky.social , and @stearnslab.bsky.social , we revealed the mammalian centriole Distal Ring architecture by combining #UExM and in situ #CryoET.
Big congrats to @ebertiaux.bsky.social and all involved.

Postdoctoral Position in Cilia-Neuroscience, Sanford Research Institute - Sioux Falls, South Dakota job with Sanford Research Institute | 39311 Join a team combining molecular neuroscience, mouse genetics, and advanced imaging to pioneer discoveries at the underexplored cilia–brain interface.

The Loukil Lab has an opening for a Postdoctoral Researcher to study primary cilia in the brain and their roles in neurological disease.
If you or someone you know might be interested, please share or reach out! 🧠✨
#Neuroscience #Cilia #Postdoc #neuro #SFN

neurojobs.sfn.org/job/39311/po...

Neuroscience Postdoctoral Position – Loukil Lab, Sanford Research - Sioux Falls, SD 57104 - Indeed.com Sanford Health

The Loukil Lab has an opening for a Postdoctoral Researcher to study primary cilia in the brain and their roles in neurological disease.
If you or someone you know might be interested, please share or reach out! 🧠✨
#Neuroscience #Cilia #PostdocJobs

www.indeed.com/m/viewjob?jk...

KIF13B controls ciliary protein content by promoting endocytic retrieval and suppressing release of large extracellular vesicles from cilia Rezi et al. show that kinesin-3 KIF13B regulates ciliary protein content by promoting endocytic retrieval and small extracellular vesicle (EV) release of ciliary proteins while suppressing their relea...

KIF13B controls ciliary protein content by promoting endocytic retrieval and suppressing release of large extracellular vesicles from cilia: Current Biology www.cell.com/current-biol...

Excited to see this work published online at @cp-cell.bsky.social today!

www.cell.com/cell/fulltex...

Our goal was to share these datasets with the scientific community to spark fresh interest in studying primary cilia roles in brain function and behavior.

Thrilled to share our new paper on the in vivo BioID of neuronal cilia 🧬🌀
This is the first look at the signaling power of neuronal primary cilia in the mature mouse brain.
Huge thanks to @sarahgoetz.bsky.social and amazing collaborators for making this possible! 🙏

www.jneurosci.org/content/45/3...

hu.MAP3.0: atlas of human protein complexes by integration of >25,000 proteomic experiments | Molecular Systems Biology imageimagehu.MAP3.0 integrates mass spectrometry experiments to identify human protein complexes. Using this resource, this study characterizes covariation of complexes, identifies mutually exclusive ...

Very excited that our work describing hu.MAP3.0 is published in @molsystbiol.org. Here we use machine learning to integrate >25k mass spectrometry experiments to place ~70% of human proteins into 15k protein complexes.

www.embopress.org/doi/full/10....

TRiC Is a Structural Component of Mammalian Sperm Axonemes The TRiC chaperonin is responsible for folding ~5%–10% of the proteome in eukaryotic cells. Our recent cryo-electron microscopy studies of axonemes from diverse mammalian cell types led to the surpri...

Please see a Perspective we wrote on our recent findings:
onlinelibrary.wiley.com/doi/full/10....

Mentoring is the most important thing most of us can do. Here is a 🧵about what I've learned as a PI running an academic research lab. I hope some of the advice is helpful to those who are just starting their labs and to folks hitting the academic job market in search of an independent position 🧪 1/n

Protein codes promote selective subcellular compartmentalization Cells have evolved mechanisms to distribute ~10 billion protein molecules to subcellular compartments where diverse proteins involved in shared functions must assemble. Here, we demonstrate that prote...

🧬🧪Protein codes promote selective subcellular compartmentalization | Science www.science.org/doi/10.1126/...
Henry Kilgore @itamarchinn.bsky.social @pgmikhael.bsky.social Ilan Mitnikov, et al. @aihealthmit.bsky.social @whiteheadinstitute.bsky.social @mitofficial.bsky.social

We got a Centrosome & Cilia starter pack 🙌 lots of space to add anyone interested!