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@florencevb.bsky.social

MD, MSc | PhD Candidate at the Netherlands Cancer Institute precision oncology | (immuno)therapy resistance | obesity

279 Followers  |  495 Following  |  3 Posts  |  Joined: 09.01.2025  |  1.5047

Latest posts by florencevb.bsky.social on Bluesky


πŸ‘πŸΌπŸ‘πŸΌπŸ‘πŸΌ

30.01.2026 09:41 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Liver metastases dampen IL18-driven Ξ³Ξ΄ T cell activity and immunotherapy responsiveness in colorectal cancer van Renterghem et al. investigate the impact of liver metastases on immunity in MMR-d/MSI-hi patients treated with ICB. They show that IL18 activates liver-derived VΞ΄1+ T cells and predicts ICB benefi...

Why do patients with liver metastases respond so poorly to cancer immunotherapy?
Here we find a new immunological mechanism in MMR-d cancers centering on IL-18 and Ξ³Ξ΄ T cells.πŸ‘‡ www.cell.com/cell-reports... @cp-cellrepmed.bsky.social

27.01.2026 14:28 β€” πŸ‘ 10    πŸ” 6    πŸ’¬ 3    πŸ“Œ 0
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Taking over the hospital for prideweek with gendercupcakes
@nkinl.bsky.social @florencevb.bsky.social #diversity

29.07.2025 12:25 β€” πŸ‘ 4    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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Drop by poster P-556 today between 18:30-20:00 and check out some of the first work of my PhD: β€œTrametinib for NRAS-mutated tumors: results from the Drug Rediscovery Protocol (DRUP)”. See you there! #EACR2025 πŸ‘―β€β™€οΈπŸ‘©πŸΌβ€πŸ”¬

17.06.2025 14:41 β€” πŸ‘ 7    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Table of new drugs approved in Q1

Table of new drugs approved in Q1

FDA new drug approvals in Q1 2025 tinyurl.com/5n8ak54h

Only 7 new drugs were approved by the FDA in Q1, but 2 are potential blockbusters - the sodium channel inhibitor suzetigrine for pain and TROP2-targeted ADC datopotamab deruxtecan for breast cancer

14.04.2025 13:56 β€” πŸ‘ 3    πŸ” 2    πŸ’¬ 1    πŸ“Œ 1
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Very inspirational two days at the Clinical Cancer Genomics conference in Amsterdam! Lots of interesting speakers on the current state of genomics and proteomics for biomarker identification and treatment decisions in daily oncological clinical practice. #CCG2025 #HartwigMedicalFoundation

21.03.2025 12:57 β€” πŸ‘ 5    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Living alone for several years and/or experiencing serial relationship break-ups are strongly linked to raised levels of inflammatory markers in the blood–but only in men

jech.bmj.com/content/76/5...

18.01.2025 17:23 β€” πŸ‘ 24    πŸ” 4    πŸ’¬ 3    πŸ“Œ 0
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Top 4 things to know about doing science:
1. You need to have someone you can talk to
2. One-on-one discussions are the best
3. Think about discussions as improvisations and use the β€˜yes, and’ rule
4. Create a safe space so both of you feel open to saying seemingly silly things

13.01.2025 01:52 β€” πŸ‘ 122    πŸ” 32    πŸ’¬ 4    πŸ“Œ 5

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