Anaya Malik

Seborrheic Dermatitis: New Pathophysiology Evidence and Therapeutic Implications Deepen your proficiency in diagnosing and treating seborrheic dermatitis with recent findings about the science behind this disease...

New @amjreviews.bsky.social infographic: Seborrheic dermatitis update, immune activation, barrier/lipid disruption, and microbiome shifts linked to disease.

www.emjreviews.com/en-us/amj/de...

This infographic publication has been supported by a Medical Education Grant from Arcutis Biotherapeutics.

Roflumilast for Psoriasis Shows Early Benefit Meta analysis suggests roflumilast improves early psoriasis outcomes versus placebo and is generally well tolerated, though more trials are needed.

In psoriasis trials, roflumilast delivered higher rates of Investigator’s Global Assessment success vs placebo at Weeks 4 and 8, with a favorable tolerability profile, signaling promise as an effective treatment option.

Details: www.emjreviews.com/en-us/amj/de...

COVID-19 Shifted Pediatric Flu Hospitalization Patterns in Children Study of 553 hospitalized children shows COVID-19 altered pediatric influenza seasonality, influenza A share, and length of stay.

Pediatric influenza hospitalizations have shifted after the COVID-19 era: altered seasonal peaks, a mix of influenza types, and modestly shorter stays.

None of the affected children were vaccinated = a clear call for stronger routine immunization strategies.

www.emjreviews.com/en-us/amj/mi...

Melanocyte Mysteries Uncovered: Interview with David Fisher Interview with David Fisher, Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA...

In this expert interview, Dr David Fisher explores key melanocyte mysteries: the surprising link between UV and endorphins, molecular drivers of pigment-related melanoma risk, and where melanoma prevention and treatment are headed.

www.emjreviews.com/en-us/amj/de...

@harvardmed.bsky.social

How Can Hematologist-Oncologists Tackle Invasive Fungal Infections? Expert Insights from Clinical Practice Expert insights from Dr Hana F. Safah on treating invasive fungal infections in hematology/oncology patients...

📢 In hematology/oncology, invasive fungal infections are increasingly frequent and hard to spot early. This interview highlights new risk factors and gaps in rapid diagnosis and future solutions.

Read more: www.emjreviews.com/en-us/amj/mi...

The publication of this article was funded by Astellas.

Time-of-Day Immunochemotherapy Improves NSCLC Survival Earlier infusions improved PFS and OS in advanced NSCLC in a Phase 3 trial.

⏰🫁🔬 NSCLC Phase 3: first 4 immunochemo cycles before 3pm linked to longer survival, with similar safety and a CD8 activation signal.

www.emjreviews.com/en-us/amj/re...

#AMJRespiratory #NSCLC #LungCancer

Vunakizumab Discontinuation Predicts Plaque Psoriasis Remission After vunakizumab discontinuation, PASI maintenance varied; BMI, interruptions, and psoriasis duration predicted relapse.

🧴🔎 20 weeks after stopping: ~73% near-clear; ~45% fully clear. Treatment interruptions and higher BMI were linked to losing response.

www.emjreviews.com/en-us/amj/de...

#AMJDermatology #Psoriasis

Do GLP-1 Receptor Agonists Raise Chronic Cough Risk? GLP 1 receptor agonists were associated with higher incident chronic cough in adults with type 2 diabetes, with risk persisting even after excluding patients with reflux diagnoses.

😮‍💨🩺 GLP-1s linked to chronic cough.

EHR data (T2D): ~12% higher risk vs other meds. Signal remained after excluding reflux (not causal).

www.emjreviews.com/en-us/amj/re...

#AMJRespiratory #Pulmonology

Mini-Clinical Evaluation Exercise Improves Resident Self-Assessment Mini-CEX self-assessment training with feedback improved dermatology residents’ clinical performance and strengthened alignment between resident and faculty ratings across multiple evaluation domains.

📊 Dermatology residents showed better self-assessment accuracy and stronger exam performance after structured mini-CEX training with feedback.

www.emjreviews.com/en-us/amj/de...

#AMJDermatology #MedicalEducation #ClinEd

Home-Based Video Exercise Program After Lumbar Surgery A home-based video-guided exercise programme improved long-term disability, function, and fear of movement after lumbar spine surgery, with early reductions in depressive symptoms versus standard care...

🎥🧠 Home video-guided exercise after lumbar surgery was linked to lower disability and less fear of movement over 24 months. QoL improved too.

www.emjreviews.com/en-us/amj/rh...

#AMJRheumatology #Rehab

Rethinking Early Intervention in Relapsing Multiple Sclerosis: A Closer Look at Long-Term Safety and Efficacy Data for Sphingosine 1-Phosphate Modulators Expert insights on the open-label DAYBREAK study of ozanimod for early relapsing MS: efficacy, long-term safety, and real-world use from...

📖 Long-term data on ozanimod informs relapse reduction, MRI lesion control, and safety considerations clinicians should know.

www.emjreviews.com/en-us/amj/ne...

#MultipleSclerosis #Neurology #AMJNeurology

This article was sponsored by Bristol Myers Squibb and is intended for US neurologists only.

HIV Post-Exposure Prophylaxis Guidance Updated Updated HIV post-exposure prophylaxis guidelines introduce new PEP regimens, shorten follow-up HIV testing, and refine management after occupational exposure when source patients have undetectable vir...

🧬 Updated HIV PEP guidance trims follow-up testing & reflects undetectable viral loads in occupational exposures.

www.emjreviews.com/en-us/amj/mi...

#AMJNeurology #HIV #PEP #InfectiousDiseases

Health Risks Signal Where Prevention May Matter Most A Danish population study linked Health Risks to 30 chronic conditions, showing stress, obesity, and sleep troubles were most consistently associated, while classic behavioural risks showed weaker pat...

🔍 Which risks drive chronic disease most strongly?
Population data show stress, obesity, and physical inactivity are consistently linked with multiple chronic conditions, outweighing several traditional risk factors.

What this may signal for prevention 👇

www.emjreviews.com/en-us/amj/ne...

Social Factors Shape Lung Cancer in Never-Smokers Chronic lung disease and socioeconomic factors were independently linked to higher lung cancer risk in never-smokers, highlighting the need for multifactorial risk assessment beyond smoking history.

🫁📊 Never-smoker NSCLC: chronic lung disease linked to ~3× higher odds. Living outside the capital city also showed higher odds.

www.emjreviews.com/en-us/amj/re...

#AMJRespiratory #LungCancer

Acne Incidence in Transgender Individuals After Testosterone Acne incidence rose sharply in transmasculine transgender individuals after testosterone, with moderate to severe cases also increasing. Clinicians should monitor closely, especially in the first year...

🧪 New cohort data examine acne incidence after testosterone therapy in transgender individuals

The study reports a rise in acne following testosterone initiation, and differences compared with cisgender cohorts over time.

www.emjreviews.com/en-us/amj/rh...

#Acne #TransgenderHealth

Volumetric Bone Loss Seen in Knee Osteoarthritis Radiographic knee osteoarthritis was associated with slightly higher DXA aBMD but lower tibial cortical volumetric bone mineral density, highlighting a potential mismatch between density measures and ...

🦴🦵 Knee OA linked to lower tibial cortical vBMD, even as DXA BMD looked slightly higher.

www.emjreviews.com/en-us/amj/rh...

#AMJRheumatology #Osteoarthritis

Shoulder Joint Range of Motion Falls After Breast Cancer Surgery Shoulder joint range of motion was limited in over 80% of patients 1 month after breast cancer surgery, with older age, more nodes removed, and total mastectomy increasing risk.

🎗️🧠 Shoulder ROM tightens: 81% limited 1 month post–breast cancer surgery. Higher risk with age, node removal, total mastectomy.

www.emjreviews.com/en-us/amj/on...

#AMJOncology #BreastCancer #Rehab

Direct Brain Drug Delivery Appears Safe in Pediatric Studies Systematic review finds convection-enhanced delivery in pediatric patients is linked mainly to low-grade adverse events, with no Grade 4 or 5 toxicity, supporting safer investigational CNS therapy del...

🧠💉Pediatric CED appears safe overall according to 12 studies (162 patients) which found mostly Grade 1–2 AEs, and no Grade 4/5 toxicity.

www.emjreviews.com/en-us/amj/ne...

#AMJNeurology #PediatricNeurology

Managing Eye-Related Adverse Events Caused by Cancer Treatments Some cancer medicines may cause problems with the eyes or with vision. In this short video, ophthalmologist Dr Neel Pasricha shares his...

👁️ Vision issues can occur with cancer treatments. Dr Neel Pasricha discusses eye-related adverse events in oncology and how to manage them. www.emjreviews.com/en-us/amj/on...

This content was funded by @astra-zeneca.bsky.social

Tick, Tick, Boom! An Update on Tickborne Infections in the United States The burden of tickborne diseases in the US more than doubled between 2004–2016, with >491,000 cases reported during this period...

🕷️ Tickborne infections are on the rise across the U.S.

Karen C. Bloch of @vanderbilt.edu breaks down current epidemiology and key clinical considerations for ID specialists.

www.emjreviews.com/en-us/amj/mi...

#InfectiousDiseases #AMJMicrobiology

Why Some Knee Osteoarthritis Pain Runs Hotter In an IMI APPROACH cohort, an inflammation biomarker subtype aligned with worse knee osteoarthritis pain outcomes across questionnaires, while MRI damage patterns mainly tracked nociceptive like pain ...

🧬🦵 Some knee OA pain runs hotter.

www.emjreviews.com/en-us/amj/rh...

Inflammation biomarker subtype tied to KOOS/WOMAC pain and PainDETECT; MRI damage showed weaker links.

#AMJRheumatology #KneeOA

Durvalumab Cost-Effectiveness in LS-SCLC Under Review Durvalumab cost-effectiveness in limited-stage small cell lung cancer failed to meet US value thresholds despite longer overall and progression-free survival. Subgroup modeling suggested better value ...

💰🫁 Durvalumab in LS-SCLC improved survival but ICER hit $383k/QALY, above US $150k threshold. Extrathoracic progression subgroup came close.

www.emjreviews.com/en-us/amj/re...

#AMJRespiratory #LungCancer

Explore our three most read stories of 2025:

The 2024 Revised McDonald Criteria: AAN 2025 Highlights
lnkd.in/eAAQ8Rpy

Investigating FDA Reports of Tirzepatide-Thyroid Cancer Connection
lnkd.in/eZZXbuRA

The Surprising Link Between Almond Consumption and Gut Health
lnkd.in/ejMBjF7F

Male Circumcision Linked to Reduced Cervical Cancer Risk A systematic review links male circumcision to significantly lower risk of Cervical Cancer and lesions in female partners. Learn the public health impacts.

🧠🩺 This meta-analysis on male circumcision and cervical cancer risk has sparked debate.

What would make this more balanced or more clinically clear (framing, context, limitations)?

www.emjreviews.com/en-us/amj/on...

#Oncology #CervicalCancer #HPV

Can Lasers And Energy-Based Devices Reverse Skin Aging? This systematic review suggests lasers and energy-based devices may reduce cellular senescence, supporting skin rejuvenation, anti-fragility, and longevity through hormetic effects on aging skin cells...

✨🔬 Review links lasers and energy-based devices to reduced cellular senescence and early signs of rejuvenation in aging skin.

www.emjreviews.com/en-us/amj/de...

#AMJDermatology #Dermatology #SkinAging

IDWeek 2025: Key Discussions and Breakthroughs ATLANTA, Georgia, USA, homebase for the CDC and a fitting stage for public health discourse, welcomed thousands of clinicians, scientists...

🧬 IDWeek 2025 recap: prevention-first HIV PrEP, RSV and maternal–infant updates, inpatient ID shifts, and leadership messages on equity and public trust, written by Dr Majd Alsoubani @tuftsmedschool.bsky.social

www.emjreviews.com/en-us/amj/mi...

AMJ Microbiology and Infectious Diseases journal is out now!

Inside, discover key insights from IDWeek 2025 from evolving strategies in HIV prevention to stewardship innovations and much more

Read the journal today: www.emjreviews.com/en-us/amj/mi...

US Inhaler Use Drives Rising Greenhouse Gas Emissions A U.S. analysis found inhalers for asthma and COPD generated nearly 25 million metric tons of CO₂ emissions between 2014 and 2024, with costs exceeding $5 billion.

💨 Inhalers prescribed for asthma and COPD in the U.S. released nearly 25 million metric tons of greenhouse gases over the last decade, 98% from metered-dose inhalers. Could greener options cut emissions?

www.emjreviews.com/en-us/amj/re...

#AMJRespiratory #ClimateHealth #Sustainability

Treating Post Acne Redness with Botulinum Toxin A Randomized split face trial suggests intradermal botulinum toxin A for post acne erythema reduces redness and sebum versus broadband light with similar short term safety.

💉 Intradermal botulinum toxin A shows strong efficacy in reducing post-acne erythema and improving skin appearance in a split-face randomized trial, with high satisfaction and minimal side effects reported by patients.

www.emjreviews.com/en-us/amj/de...

#AMJDermatology #AestheticMedicine

Understanding Persistent Idiopathic Facial Pain in Practice This commentary on persistent idiopathic facial pain urges balanced dental and neurologic assessment, clearer differential diagnosis with migraine, and pragmatic combined behavioral and pharmacologic ...

🧩 Interdisciplinary guidance redefines persistent idiopathic facial pain as a shared challenge for neurologists and dentists, calling for coordinated assessment and integrated behavioral and pharmacologic care.

www.emjreviews.com/en-us/amj/ne...

#AMJNeurology #ChronicPain #FacialPain