Louis-Marie Bobay

My book is available for pre-order!
www.routledge.com/Quantitative...

Or you can request an inspection copy here:
www.routledge.com/textbooks/ev...

Postdoctoral position - Synthetic Biology / Bacterial Immunity - Research The Bikard lab at Institut Pasteur in Paris is seeking to hire postdoctoral researchers. We are investigating bacteria / bacteriophages interactions, and the genetic innovation that happens at this in...

🚨 Hiring Alert! 🚨My lab at Institut Pasteur is recruiting several Postdocs! We have exciting open projects in: 🦠 Synthetic Biology and🛡️ Bacterial Immunity. Come do great science with us in the middle of Paris! 🇫🇷🥐 research.pasteur.fr/en/job/postd...

My pleasure! Those were busy times for you indeed! Congrats on all these accomplishments.

Congrats to @carolinamicro.bsky.social for leading this study! We looked at genome rearrangements over short evolutionary timescales. Among other things, we found that genomes are highly syntenic within most species. However, several bacteria experienced sudden and massive genome rearrangements.

Baby-to-baby strain transmission shapes the developing gut microbiome - Nature A metagenomic survey of babies attending the first year of nursery detected extensive baby-to-baby microbial strain transmission, pointing to social interactions in infancy as crucial drivers of infan...

🥁 NEW

Our study on infant gut microbiome and #straintransmission is now published in @nature.com:

doi.org/10.1038/s415...

1/10

Characterizing a novel Symbiopectobacterium purcellii MEX strain at the early stages of establishing a symbiotic relationship Abstract. Insects ally with microbial symbionts for a diversity of services. The range of these interactions is wide, spanning from beneficial to pathogeni

I’m excited to share a new paper by a super talented graduate-student-now-postdoc. Grateful to work with old and new collaborators!

Characterizing a novel Symbiopectobacterium MEX strain at the early stages of establishing a symbiotic relationship url: academic.oup.com/gbe/article/...

Deadline is approaching (Feb 9) to apply for a PI position at Institut Pasteur. Come join us and contribute to an amazing scientific environment!!!

a quick reminder!

Une opportunité unique de former des étudiants talentueux à la biologie des bactéries à l'ENS Lyon et mener des recherches sur les phages, l'immunité bactérienne, le transfert génétique horizontal (HGT) et/ou les éléments génétiques mobiles au sein du département de bactériologie du CIRI.

Creating bacterial genomic diversity through large-scale reconfigurations reveals phenotype robustness to organizational genome change
doi.org/10.64898/202...

The distinction between virulent & temperate phages gets fuzzier if one can find so many virulent phages in the sequences of bacterial genomes coming from standard lab "pure" cultures. Check Peter's thread on our work and the N&V by Carson & Hynes: doi.org/10.1038/s415...
#phagesky #microsky

Congratulations! Amazing work!

If you are interested in this work and are looking for a postdoc position, please get in touch -- we are actively looking for someone to join our group at UCLA!

Recombination between strains fuels pervasive adaptive evolution among human gut commensal bacteria, and strongly implicate host diet and lifestyle as critical selection pressures @nature.com @nanditagarud.bsky.social
www.nature.com/articles/s41...

Looking for a postdoc in 2026? The Ewel fellowship at UF provides $70K salary and $20K research support for 2 yrs. I'm happy to sponsor a postdoc interested in microbial ecology of Florida coastal ecosystems (seagrass, coral, mangroves, springs). 🦠 Due 1/11/26

postdoc.aa.ufl.edu/current-post...

We are recruiting a Lab Manager/Research Specialist
jobs.ncsu.edu/postings/225...
Please re-post, thank you

Screenshot from GRC portal confirming microbial population biology meeting June 27, 2027 in Andover, New Hampshire.

It’s officially happening folks! The Microbial Population Biology Gordon Research Conference is back in Andover, New Hampshire starting June 27th of 2027!
See you there!!

@wcratcliff.bsky.social @ksbakes.bsky.social @surtlab.bsky.social

#microsky #mevosky

Are you a recombination researcher heading to #SMBE2026? Submit your abstract to our Symposium, organised by Marie Raynaud, Laurent Duret, and myself. We're excited to have Aurora Ruiz-Herrera from UAB Barcelona as our invited speaker.
🧬🦄🦠🌿🐝🐟🍄🪱
@aruizherrera.bsky.social @duret-lbbe.bsky.social

Creation of new junior research groups at the Institut Pasteur - Call for applications 2026 - Research The Institut Pasteur is launching an international call to recruit new junior research group leaders leveraging cutting-edge transdisciplinary approaches to exploring infectious diseases, host-microbe...

🔬 Call to create junior research groups at the Institut Pasteur

Focus: Infectious diseases, host-microbe interactions, vaccines
Special interest: AI methodologies

📅 Deadline: Feb 9, 2026
👥 2-12 years post-PhD

Apply now 📝 research.pasteur.fr/en/call/crea...

#JobOpportunity #Research

Mid-career Group Leader position in AI in genomics at Institut Pasteur, Paris - Research Institut Pasteur and the CNRS are launching a call for a mid-career group leader position in AI in genomics. We are looking for an experienced researcher (typically with > 8 years of research experien...

Opening of a Group Leader position in AI in genomics at Institut Pasteur @pasteur.fr , Paris research.pasteur.fr/en/call/mid-...

Natural and artificial variations of the standard genetic code www.cell.com/current-biol...

Pangenomic visualization of the genomic organization of all 12 Streptomyces isolates representing each of the four AC groups. Hierarchical clustering is based on orthogroup presence/absence using Euclidean distance and Ward’s linkage method. Colored rings show orthogroup presence/absence per isolate, the outer ring shows the number of contributing genomes, and the second outer ring shows the number of genes present in each orthogroup. The metadata table shows 1) experimental phenotype data (orange) of total siderophore production (SP, halo size on CAS-LB media), growth under osmotic stress (OST, 1.0M sorbitol), and the relative production of four individual siderophores in response to media supplemented with drought- vs. well-watered root tissue (EF1 and EF2, ferrioxamine EF; H, O-methyl desferrioxamine H, D4, derrioxamine D4), and 2) genome analysis data (dark blue), showing the number of gene copies that match with specific COG function search terms related to iron acquisition (iron and Sid, siderophores), carbon resource utilization (G-3-P, glycerol-3-phosphate), and osmotic stress response (ProP, FabG, OmpR, Kdp, Trk). Scale values represent Z-scores, where darker blue indicates more gene copies, and darker orange indicates more siderophore production, more growth under osmotic stress, or a larger halo.

How do root #microbes respond to drought? This study finds that #Streptomyces responses are strain-specific & functionally diverse, with traits & #plant effects varying independently of phylogeny, stressing the need to resolve functional traits at the strain level @plosbiology.org 🧪 plos.io/4owtjIT

metaTraits: a large-scale integration of microbial phenotypic trait information Abstract. Microbes differ greatly in their organismal structure, physiology, and environmental adaptation, yet information about these phenotypic traits is

metaTraits: a large-scale integration of microbial phenotypic trait information

academic.oup.com/nar/advance-...

Evaluating the early diversification of Yersinia pestis and its phylogeographic expansion over 96 years of evolution in Madagascar - Communications Biology A comprehensive phylogenetic analysis of Yersinia pestis, the causative agent of plague, provides insight into the diversity and evolution of this pathogen in Madagascar. This study provides valuable ...

Another addition to the 2nd Plague Pandemic bibliography. Why, when this relates to the 3rd Pandemic, instead of the 2nd? B/c the science about plague we've acquired from the unfortunate experience of Madagascar informs everything we can do in #medhist. www.nature.com/articles/s42...

🧬🛡️How are new immune mechanisms created?

We show how Lamassu antiphage system, originated from a DNA-repair complex and evolved into a compact and modular immune machine, wt Dinshaw Patel lab in @pnas.org.
👏 @matthieu-haudiquet.bsky.social, Arpita Chakravarti & all authors!

doi.org/10.1073/pnas...

Long-read metagenomics reveals phage dynamics in the human gut microbiome - Nature Complex prophage integration dynamics, including low-level induction, cross-family host range and transposase-mediated mobilization, challenge existing paradigms and deepen our understanding of phage–...

Long read Metagenomics, #phage and #prophage in the gut by Ami Bhatt's group. Beautiful data showing changes in phages over two years

#phagesky

www.nature.com/articles/s41...

Some fantastic sessions being planned for ASM Microbe 2026, including "Long-term Dynamics of Environmental Microbiomes", and "Eco-evolutionary Dynamics of Phages and Their Roles in Horizontal Gene Transfer". Get your abstract(s) ready, and join us June 4–7, 2026 in D.C. ! asm.org/events/asm-m...

Due to the shutdown, NIH cancelled >370 study sections, impacting >24,000 applications

Rescheduled meetings will only discuss 30-35% of applications, have simplified summary statements (no narrative paragraph), and a new category - "competitive but not discussed"

grants.nih.gov/grants/guide...

Bacterial immune systems as causes and consequences of microbiome structure Bacterial immune systems have evolved in response to diverse molecular "parasites", yet their ecological roles remain poorly understood. This Essay explores how interactions between mobile genetic…

The ecological roles of bacterial #immune systems are poorly understood. Rafael Custodio @ellinoralseth.bsky.social @brockhurstlab.bsky.social @brownlab.bsky.social & Edze Westra explore how mobile genetic elements and bacterial defenses shape #microbiome structure and function 🧪

Review: Inference and applications of ancestral recombination graphs https://www.nature.com/articles/s41576-024-00772-4 (read free: https://rdcu.be/dVyQH) 🧬🖥️