Caity Holmes

We are SO EXCITED for year 6 of the Klebsiella Seminar Series! The session themes, keynote speakers, and dates are below. Registration is free and abstract submission is now open!

Thank you, Olaya! Excited to read your new pre-print today!

Our latest collaboration with Karthik Hullahalli's team on bacterial barcoding is now out! We developed a way to measure dissemination dynamics that controls for independent colonization events. This more accurately assesses how bacteria spread between tissues.

journals.asm.org/doi/10.1128/...

Year 6 planning is in progress! We're excited for another great year of Klebsiella science.

UMN's Department of Microbiology and Immunology is hiring! Come be our colleague in the Twin Cities! Searches are open for Virology and Fungal Biology (links below).

Virology: hr.myu.umn.edu/jobs/ext/365...
Fungal Biology/Medical Mycology: hr.myu.umn.edu/jobs/ext/365...

Mark your calendars! #mmpc2026 The 2026 Midwest Microbial Pathogenesis Conference will be take place September 25-27, 2026 at the University of Minnesota! We are excited to welcome keynote speaker Dr. Andy Camilli. Give us a follow and watch for important information here ➡️ mmpc2026.umn.edu

Job alert ‼️ UChicago Micro is hiring! Open to tenured/tenure track faculty at all levels in any area of microbiology. Come join our amazing and growing department. apply.interfolio.com/174404

Such an exciting milestone! Congrats! 🎉

So happy to see this in print and to collaborate on this project!

Thank you, Seb! 😊

The Holmes Lab is now open! I'm really grateful to be taking on the next chapter here in Minnesota! ✨

sites.google.com/umn.edu/holm...

Join us next week for Session 1 of this year's Klebsiella Seminar Series! I am really looking forward to these talks on pathogenesis. We are excited to be returning for ⭐Year 6⭐ of the series!

Figure summarizing the regulatory effects induced by the gastrointestinal tract environment on Klebsiella pneumoniae, leading to T6SS-mediated killing of Betaproteobacteria.

Klebsiella pneumoniae uses a type VI secretion system to overcome microbiota-mediated colonization resistance

@azmicro.bsky.social @emorydeptofmed.bsky.social

#microbiome #bacteria #pathogens #microbiology

www.nature.com/articles/s41...

Submit your abstract for the 6th Klebsiella Seminar Series until Friday 21st!
Registration is free!
Follow the link bellow!
👇🏻👇🏻

I had two grant proposals up for review in the NIH Bacterial Virulence (BV) study section. It was canceled without notice this morning.
Without those grants, my lab must close within a year.
And so the purge of scientific research in the US continues
🤬
#MicroSky 🦠🧫🧪🧬🔬

After 6 wonderful years at Wake Forest School of Medicine the Zafar lab is now officially open at Emory School of Medicine in the dept. of microbiology and immunology!

Save NIH and NSF Research Funding ⭑ 5 Calls On February 7, the Trump administration moved to cut billions of dollars in funding from the National Institutes of Health (NIH) and National Science …

A useful tool and a great thing to do...

5calls.org/issue/nih-ns...

ASM did a spotlight article on me last February and it has also been taken down as “under review”. Other spotlight articles are still up so not sure how else to interpret this besides the obvious. It feels pretty crappy to have been singled out and I won’t be engaging with them in the future.

Thank you to all collaborators for helping to sort through this huge set of data and to the barcoding community for your help in comparing our trends to other systems! This is truly a study were I made friends and collaborators along the way. ⭐

Klebsiella leaves the lung in two distinct patterns, termed "metastatic" and "direct", which are defined by the extent of clonal replication in primary tissues and predict bacterial burden across sites. Oxidative stress from the host and bacterial LPS influences these patterns.

Patterns of Klebsiella pneumoniae bacteremic dissemination from the lung - Nature Communications Tracing barcoded clones of Klebsiella pneumoniae during pneumonia with bacteremia, Holmes and colleagues identify two modes of dissemination, with high or low bacterial burdens, and define the host an...

I am excited to announce our latest publication! We teamed up with @khullahalli.bsky.social to barcode Klebsiella and ask basic questions about bacteremia pathogenesis: 1) how are bacteria shared between sites and 2) which host and bacterial factors influence dynamics?
www.nature.com/articles/s41...

Klebsiella Seminar Series 2025 This form can be used to register only or register+submit an abstract for the 2025 Klebsiella Seminar Series. By registering, you will receive a Zoom Webinar link for attendance prior to the event. Re...

It's that time of year! Registration and abstract submission for the 6th Klebsiella Seminar Series is now open. Participation is free and abstracts are due by February 16th. See the link below for details, and reach out to the organizers with any questions:
forms.gle/gxbvaC6FjzuS...
#KlebClub

🙌 Congrats to you both!!

Diverse polysaccharide production and biofilm formation abilities of clinical Klebsiella pneumoniae - npj Biofilms and Microbiomes npj Biofilms and Microbiomes - Diverse polysaccharide production and biofilm formation abilities of clinical Klebsiella pneumoniae

Check out our latest publication aligning the MRSN panel biofilm and mucoid phenotypes to the genotypes in npj Biofilms and Microbiomes!

Special thanks to my collaborators on this work
@olayarendueles.bsky.social and Taj Azarian!

www.nature.com/articles/s41...

Hi Natalia, could you add me please?

Excited for my first bluesky post announcing TWO openings for tenure track positions in virology! I am chair of the search committee and with a new department head Mike Gale we are in an exciting building phase.

Please share with anyone who might be interested: hr.myu.umn.edu/jobs/ext/365...

Let's increase #klebclub chatter on 🔵🦋!
Klebsiella aficionados add your handle below and we will build a starter pack.

🔁 to spread the word

Thanks, Matt! Can you please add me to the list?

New commentary!🦠In this mSphere of Influence article, I talk about my fascination with host-pathogen interactions during systemic infection and highlight two studies that have been significant in developing this interest.

journals.asm.org/doi/10.1128/...