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SandkvistLab

@sandkvistlab.bsky.social

47 Followers  |  58 Following  |  1 Posts  |  Joined: 09.05.2025  |  1.3097

Latest posts by sandkvistlab.bsky.social on Bluesky

Thank you, Olivera!

02.10.2025 17:47 — 👍 0    🔁 0    💬 0    📌 0
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Acinetobacter Baumannii Secreted Protease CpaA Inhibits Factor XII-Mediated Bradykinin Generation and Neutrophil Activation | Circulation Research BACKGROUND: FXII (coagulation factor XII) is best known for its roles in the contact and kallikrein-kinin pathways. FXII is converted to its active enzyme (FXIIa [activated factor XII]) by PKa (plasma...

www.ahajournals.org/doi/10.1161/... @drbadbug.bsky.social A role for FXII in responding to bac. infection & suggests that by inhibiting the contact & KKSs & impairing neutrophil activation, CpaA may blunt the innate immune response/help prevent the elimination of A baumannii from the human host.

20.05.2025 11:23 — 👍 3    🔁 2    💬 0    📌 0

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