Henrik Strahl's Avatar

Henrik Strahl

@henrikstrahl.bsky.social

Microbiology Prof at the Centre for Bacterial Cell Biology, Newcastle University. Research focus on antibiotics, AMR and bacterial cell envelopes, ๐Ÿ‡ซ๐Ÿ‡ฎ

1,133 Followers  |  932 Following  |  57 Posts  |  Joined: 28.09.2023  |  1.8867

Latest posts by henrikstrahl.bsky.social on Bluesky

Looking for a PhD opportunity in Microbiology? Consider joining one of the UK's leading microbiology research clusters at Newcastle University. See the thread for MRC DTP studentships currently advertised. @medicalsciencesncl.bsky.social @sagencl.bsky.social @cbcb-newcastle.bsky.social #microsky

04.11.2025 10:54 โ€” ๐Ÿ‘ 16    ๐Ÿ” 18    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
Preview
MRC DiMeN Doctoral Training Partnership: Hiding in plain sight: How multi-drug resistant pathogens evade detection and killing by human neutrophils at Newcastle University on FindAPhD.com PhD Project - MRC DiMeN Doctoral Training Partnership: Hiding in plain sight: How multi-drug resistant pathogens evade detection and killing by human neutrophils at Newcastle University, listed on Fin...

If you are interested in researching how drug resistant bacteria evade killing by our immune system, them this PhD project is for you. Come join the our team at Newcastle, in collaboration with University of Liverpool, and lead research at the interface of microbiology, immunology and metabolomics.

02.11.2025 20:22 โ€” ๐Ÿ‘ 13    ๐Ÿ” 18    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 1
Preview
MRC DiMeN Doctoral Training Partnership: Molecular mechanism of slow growth and antibiotic tolerance in Mycobacterium tuberculosis using single-molecule microscopy at Newcastle University on FindAPhD.... PhD Project - MRC DiMeN Doctoral Training Partnership: Molecular mechanism of slow growth and antibiotic tolerance in Mycobacterium tuberculosis using single-molecule microscopy at Newcastle Universit...

Interested in a PhD at the intersection of biophysics and microbiology?

Apply for this MRC-funded opportunity at Newcastle University to do cutting-edge microscopy in Mycobacterium tuberculosis! ๐Ÿ”ฌ๐Ÿฆ 

Closing 4 Dec!

www.findaphd.com/phds/project...

31.10.2025 13:09 โ€” ๐Ÿ‘ 26    ๐Ÿ” 32    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 3
Preview
MRC DiMeN Doctoral Training Partnership: Targeting thioredoxin reductase to combat antifungal resistance in Candida spp. at Newcastle University on FindAPhD.com PhD Project - MRC DiMeN Doctoral Training Partnership: Targeting thioredoxin reductase to combat antifungal resistance in Candida spp. at Newcastle University, listed on FindAPhD.com

Want to work within a multidisciplinary group to combat antifungal resistance in Candida spp? Fully-funded MRC PhD studentship in collaboration with @nclfungalgroup.bsky.social and Francesco Del Carratore on the mode of action of a new class of antifungal drugs. www.findaphd.com/phds/project...

31.10.2025 10:35 โ€” ๐Ÿ‘ 6    ๐Ÿ” 8    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
Preview
MRC DiMeN Doctoral Training Partnership: Structural and Functional Analysis of Drug Resistance in Tuberculosis via a Novel MmpL3 Binding Site at Newcastle University on FindAPhD.com PhD Project - MRC DiMeN Doctoral Training Partnership: Structural and Functional Analysis of Drug Resistance in Tuberculosis via a Novel MmpL3 Binding Site at Newcastle University, listed on FindAPhD....

PhD opportunity with me and @kshbeckham.bsky.social

www.findaphd.com/phds/project...

31.10.2025 11:13 โ€” ๐Ÿ‘ 10    ๐Ÿ” 10    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
Post image

๐Ÿ“ข Postdoc position: Cell Biology of Cyanobacteria

in my group, as part of the Excellence Cluster "Microbes for Climate" (M4C) in Marburg, Germany.

More information at shorturl.at/wNnDT (see Project 2)

๐Ÿ”—Apply at shorturl.at/VsEDl
๐Ÿ“…Deadline: Nov 16, 2025

Please repost. #Postdoc

02.11.2025 19:13 โ€” ๐Ÿ‘ 52    ๐Ÿ” 49    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 1

#microsky

01.11.2025 11:12 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
MRC DiMeN Doctoral Training Partnership: Resensitisation of antibiotic-tolerant Staphylococcus aureus small colony variants at Newcastle University on FindAPhD.com PhD Project - MRC DiMeN Doctoral Training Partnership: Resensitisation of antibiotic-tolerant Staphylococcus aureus small colony variants at Newcastle University, listed on FindAPhD.com

Looking for an AMR-themed PhD project? Join us to investigate antibiotic tolerance in Staphylococcus aureus through a fully funded MRC DTP PhD studentship starting in September 2026.

This project is close collaboration with @kateduncan.bsky.social and @mycobacterium-ncl.bsky.social.

01.11.2025 11:11 โ€” ๐Ÿ‘ 13    ๐Ÿ” 14    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0

If youโ€™re interested in metals, microbes and maths ๐Ÿค˜ - please check out this PhD on the impact of metals on microbial communities with @thecopperdoctor.bsky.social @blindmath.bsky.social Denis Patterson and myself, youโ€™d be based in Durham & be part of a vibrant interdisciplinary research group

29.10.2025 14:49 โ€” ๐Ÿ‘ 11    ๐Ÿ” 16    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Post image

Please RT. Post-doc opportunity alert! ๐Ÿ’ฅ closing 10th December.. Come join our team (www.thelowlab.org) at Imperial, London, working on the structure and mechanism of bacterial secretion systems.

For more details and to apply please see

www.imperial.ac.uk/jobs/search-...

29.10.2025 17:11 โ€” ๐Ÿ‘ 48    ๐Ÿ” 40    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
Preview
Using super-resolution microscopy to investigate the mechanistic principles of bacterial cell wall remodelling at University of Warwick on FindAPhD.com PhD Project - Using super-resolution microscopy to investigate the mechanistic principles of bacterial cell wall remodelling at University of Warwick, listed on FindAPhD.com

PhD project available in my lab. Email me with CV if interested
www.findaphd.com/phds/project...
#microsky #bioimaging

22.10.2025 08:28 โ€” ๐Ÿ‘ 22    ๐Ÿ” 28    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Looking forward seeing some Cdiff under the microscope! ๐Ÿ”ฌ

22.10.2025 16:27 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Post image Post image

The #SalgadoLab has now officially moved into @cbcb-newcastle.bsky.social! Thank you to amazing lab members Anna, Ella and Pavi for making it happen and @henrikstrahl.bsky.social Kasia, Charles, Tom, Amandeep, Julie and everyone at CBCB! Looking forward to working closely with everyone! #microsky

22.10.2025 16:17 โ€” ๐Ÿ‘ 30    ๐Ÿ” 1    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 1

We had a small lucky break in clouds..

18.10.2025 20:55 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Post image 18.10.2025 20:49 โ€” ๐Ÿ‘ 18    ๐Ÿ” 1    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0

#MicroSky

17.10.2025 06:56 โ€” ๐Ÿ‘ 5    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
Study Reveals 'Alarming' Rise of Superbugs in Newborn Babies Humanity's war against drug-resistant microbes is not going very well.

#AMR - no one is safe until everyone is safe

"These bugs have long been considered to only cause infections in older babies, but are now infecting babies in their first days of life"
#AntimicrobialResistance
www.sciencealert.com/study-reveal...

13.10.2025 08:42 โ€” ๐Ÿ‘ 43    ๐Ÿ” 21    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Post image

Very exciting to have Prof Mark Blaskovich @medicalsciencesncl.bsky.social (hosted by @henrikstrahl.bsky.social) all the way from the University of Queensland, Australia to give a seminar on collaborative approaches to combat antimicrobial resistance #drugdiscovery #AMR #antibiotics

07.10.2025 10:07 โ€” ๐Ÿ‘ 11    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 2

Independent research fellowships leading to tenured positions at the John Innes Centre.

Repost = nice. Thank you very much!!!

03.10.2025 16:06 โ€” ๐Ÿ‘ 49    ๐Ÿ” 87    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 4
Preview
Structure of a distinct ฮฒ-barrel assembly machinery complex in the Bacteroidota - Nature Microbiology Structural and functional characterization of the ฮฒ-barrel assembly machinery complex in Bacteroidota reveals a distinct, seven-component complex with a large extracellular domain that may enable ฮฒ-barrelโ€“surface lipoprotein complex assembly.

Our paper on the Bacteroidota BAM complex is out in @natmicrobiol.nature.com! With @madejmar.bsky.social

We found that BAM in Bacteroides and Porphyromonas gingivalis has a distinct architecture from BAM in Proteobacteria.

doi.org/10.1038/s415...

02.10.2025 06:20 โ€” ๐Ÿ‘ 53    ๐Ÿ” 23    ๐Ÿ’ฌ 4    ๐Ÿ“Œ 2

Check it out! A proper team effort from past and present group members and a great collaboration with @sergemostowylab.bsky.social

05.10.2025 08:11 โ€” ๐Ÿ‘ 33    ๐Ÿ” 19    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
Comprehensive genetic interaction analysis of the Bacillus subtilis envelope using double-CRISPRi Koo et al. apply genome-scale double-CRISPRi to map cell envelope gene interactions in Bacillus subtilis, revealing >1,000 genetic interactions and uncovering gene networks in envelope biogenesis and ...

Also see the accompanying paper from Carol Gross' lab that used a similar approach for Bacillus subtilis: www.cell.com/cell-systems...

04.10.2025 08:48 โ€” ๐Ÿ‘ 6    ๐Ÿ” 7    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Finally out, such an awesome piece of work, very proud of this one: www.cell.com/cell-systems... #MicroSky

04.10.2025 08:48 โ€” ๐Ÿ‘ 62    ๐Ÿ” 27    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 1
Preview
A Protein Antibiotic Inhibits the BAM Complex to Kill Without Cell Entry Many antibiotics are ineffective against Gram-negative pathogens such as Pseudomonas aeruginosa because they cannot penetrate the bacterial outer membrane. Here, we show that protein antibiotics calle...

The outer membrane of Gram-negative bacteria blocks many antibiotics. Our latest work reveals that L-type pyocins bypass this barrier by inactivating the BAM complex, killing Pseudomonas aeruginosa without entering the cell, providing a new blueprint for beating antibiotic resistance.

20.09.2025 09:29 โ€” ๐Ÿ‘ 71    ๐Ÿ” 37    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 4
Preview
A porin-like protein used by bacterial predators defines a wider lipid-trapping superfamily Nature Communications - This study reveals that an outer membrane protein from the predator Bdellovibrio bacteriovorus forms a pentameric assembly that traps a lipid monolayer within. This allows...

New paper out, with a contribution from Dom Gurvic and I; led by Andy Lovering and @lalouxlab.bsky.social:
www.nature.com/articles/s41...

07.07.2025 10:00 โ€” ๐Ÿ‘ 33    ๐Ÿ” 8    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1

#microsky

09.09.2025 07:18 โ€” ๐Ÿ‘ 7    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Previous preprint is now published in RSC Chemical Biology.
If you are interested in plasma membrane labeling, see the paper! ๐Ÿ‘‡
pubs.rsc.org/en/content/a...

08.09.2025 08:02 โ€” ๐Ÿ‘ 91    ๐Ÿ” 36    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 2

#MicroSky

22.08.2025 07:35 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

This manuscript originated from a nice collaboration with Tjeerd van Rij from DSM-Firmenich and Colin Harwood.

22.08.2025 07:29 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
Preview
Monitoring single cell bioenergetic status and cell lysis in dense and differentiating Bacillus subtilis cultures Bacillus subtilis is a major model organism for studying population heterogeneity in clonal bacterial cultures due to its high genetic tractability and ability to differentiate into subpopulations wit...

A new methods paper from us, this time with a focus on reliable monitoring membrane potential and cell lysis at different growth stages and cell densities. Also, note the surprisingly high level of background lysis in seemingly healthy B. subtilis cultures.
www.biorxiv.org/content/10.1...

22.08.2025 07:24 โ€” ๐Ÿ‘ 31    ๐Ÿ” 13    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 1

@henrikstrahl is following 20 prominent accounts