Jessica Beserra Felix, PhD's Avatar

Jessica Beserra Felix, PhD

@jessicab-felix.bsky.social

Adipose tissue metabolism @BaylorCollegeofMedicine . Current postdoc @GladstoneInstitutes

89 Followers  |  213 Following  |  8 Posts  |  Joined: 12.11.2024  |  1.8328

Latest posts by jessicab-felix.bsky.social on Bluesky

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N-acetylaspartate from fat cells regulates postprandial body temperature - Nature Metabolism Aspartoacylase expression in white adipose tissue regulates circulating levels of N-acetylaspartate, which in turn modulates plasma pyrimidine levels and regulates postprandial body temperature.

RESEARCH | πŸ§ͺ
@jessicab-felix.bsky.social , S Hartig et al
@bcmfromthelabs.bsky.social

N-acetylaspartate from fat cells regulates postprandial body temperature

16.09.2025 16:35 β€” πŸ‘ 5    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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N-acetylaspartate from fat cells regulates postprandial body temperature Nature Metabolism, Published online: 23 July 2025; doi:10.1038/s42255-025-01334-6Aspartoacylase expression in white adipose tissue regulates circulating levels of N-acetylaspartate, which in turn modulates plasma pyrimidine levels and regulates postprandial body temperature.
23.07.2025 14:31 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Much ado about NAA-thing Nature Metabolism, Published online: 23 July 2025; doi:10.1038/s42255-025-01327-5A recent study in Nature Metabolism by Felix et al. reveals that the breakdown of N-acetylaspartate (NAA) by the enzyme aspartoacylase (encoded by Aspa) in adipocytes has a crucial role in regulating circulating NAA levels, maintaining systemic glucose homeostasis and controlling postprandial body temperature.
23.07.2025 14:31 β€” πŸ‘ 1    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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N-acetylaspartate from fat cells regulates postprandial body temperature Nature Metabolism - Aspartoacylase expression in white adipose tissue regulates circulating levels of N-acetylaspartate, which in turn modulates plasma pyrimidine levels and regulates postprandial...

It's been a long time coming but my PhD paper is finally published. Check it out! @naturemetabolism.bsky.social urldefense.proofpoint.com/v2/url?u=htt...

23.07.2025 15:00 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

My favorite topic!

12.06.2025 06:21 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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At the Bay Area Aging Meeting today. Excited to hear some interesting science

27.05.2025 17:25 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Towards a consensus atlas of human and mouse adipose tissue at single-cell resolution Nature Metabolism, Published online: 13 May 2025; doi:10.1038/s42255-025-01296-9In this Review, the authors present a roadmap towards achieving consensus on development, analysis and interpretation of single-cell transcriptomics data in adipose tissue, including discussion of roadblocks, best practices and ideal cell-type markers for annotation of adipose tissue cell types in mice and humans.
13.05.2025 19:11 β€” πŸ‘ 10    πŸ” 6    πŸ’¬ 0    πŸ“Œ 2
Marathon runners

Marathon runners

✨New issue! ✨

Check out the latest in #metabolism research.

Read about #Metabolism in the #Brain, #Liver, #Gut, #AdiposeTissue, Protein #Lactylation, #IntermittentFasting - and other topics!

https://bit.ly/4cMZTlz

25.04.2025 15:16 β€” πŸ‘ 8    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0
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Red Blood Cells Serve as a Primary Glucose Sink to Improve Glucose Tolerance at Altitude High altitude conditions result in improved glucose tolerance and lower diabetes risk across species, yet the underlying physiological mechanism remains unclear. Using mouse models, we found that hypo...

New pre-print from the Jain Lab
www.biorxiv.org/content/10.1...

28.04.2025 21:18 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Beige fat appearance during lipoatrophy reveals trade-offs between metabolic homeostasis and female fertility White adipose tissue (WAT) meets the energetic demands required for estrous cycle regularity, ovulation, and reproductive success in women. Here, we report WAT loss and subsequent female-specific comp...

Check out this new pre-print from the Hartig Lab! Interesting study on the role of adipose tissue in female mice www.biorxiv.org/content/10.1...

28.04.2025 17:44 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

It is indeed my understanding that most research institutions won't survive if this is implemented. I know I will contact my congress and senate members.

5calls.org

07.02.2025 23:37 β€” πŸ‘ 58    πŸ” 33    πŸ’¬ 3    πŸ“Œ 2

I definitely already went on the website for the conference. Great lineup!

09.01.2025 00:32 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Looking for metabolism seminar recommendations and links to watch in 2025, preferably adipose tissue metabolism but also interested in other other aspects.

08.01.2025 17:53 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

That sounds like exactly what I want to work on in the future!

08.01.2025 17:50 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

@jessicab-felix is following 20 prominent accounts