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WilhelmssonLabChalmers

@wilhelmssonlab.bsky.social

Fluorescence, RNA, DNA, RNA therapeutics, spectroscopy, microscopy, optical tweezers, nucleic acid conformation and dynamics

29 Followers  |  44 Following  |  6 Posts  |  Joined: 07.05.2025  |  1.6058

Latest posts by wilhelmssonlab.bsky.social on Bluesky

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Happy to share that we have a paper out in JBC. Here we develop an adenine analogue for in vitro transcription fluorescence labeling. The labeled mRNA can then be used for cell uptake studies and protein expression. Great job by all co-authors!

www.sciencedirect.com/science/arti...

17.11.2025 07:51 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Excited to be here!

06.10.2025 08:09 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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First meeting with all doctoral students in our EU project @mechanism-network.bsky.social in Cologne at Stephanie Kath-Schorr's dept @kathlab.bsky.social this week. Coordinator Fredrik Westerlund @westerlundlab.bsky.social kicking it off. Great to meet all!

06.10.2025 08:01 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Monitoring Nucleoside Metabolism in Living Cells with a Nucleobase Analogue via Fluorescence Lifetime Imaging To overcome challenges in fluorescence labelling of RNA inside living cells we have recently introduced a direct approach using the fluorescent nucleobase analogue 2CNqA. Here we demonstrate its poten...

Accepted article published online today. Great work by Pauline Pfeiffer and the rest of the team! Here we follow nucleotides and cellular RNA inside live cells by metabolic labelling and FLIM. pubs.rsc.org/en/Content/A...

22.08.2025 07:02 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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So incredibly happy for and proud of my PhD student Pauline Pfeiffer who got her PhD thesis printed today! What a book! PhD defense on September 12.

20.08.2025 17:00 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Marcus Wilhelmsson is Professor at Chalmers University of Technology, working with nucleobase modifications, for example, for fluorescence labeling. He will host one student who develops novel nucleobase analogues that will facilitate single-molecule biophysics studies. @wilhelmssonlab.bsky.social

11.08.2025 08:28 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
Erwin Peterman: Home Professor Physics of Living Systems; Photo Credit: Patrick Siemons)

Erwin Peterman is a professor at VU University Amsterdam and an expert on combining fluorescence with optical tweezers. He will host 1 student within MeChaNiSM, who will study novel fluorescently modified nucleic acids, including base analogs with these tools. www.nat.vu.nl/~erwinp

23.06.2025 13:11 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

Jocelyne Vreede is a professor at University of Amsterdam, using molecular simulation to study nucleic acids in atomistic detail. She will host 2 students within MeChaNiSM to characterise how modified bases and small molecules affect nucleic acid structure and dynamics. @vreedecompchem.bsky.social

17.06.2025 07:55 β€” πŸ‘ 5    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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MeChaNiSM Mechanical Characterization of Nucleic acids using Single Molecule techniques

Our lab is happy to be part of EU doctoral network MeChaNiSM www.chalmers.se/en/projects/.... Glad to have the PhD students at Chalmers in place and looking forward to full speed ahead in the project.

10.05.2025 06:04 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

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