Achilles Kapanidis

DNA (once more) lights the way! Very excited re the fluorogenic saga manuscript - big congrats to @mirjamku.bsky.social (tremendous effort!) for leading this and to all the team of contributors.

14.07.2025 11:52 — 👍 12    🔁 2    💬 0    📌 1

A fantastic meeting, and this one looks even more special! Well done to Picoquant!

06.03.2025 18:49 — 👍 3    🔁 0    💬 1    📌 0

The RNA helicase HrpA rescues collided ribosomes in E. coli Antibiotics that inhibit ribosomes lead to collisions on mRNAs when upstream ribosomes catch up with stalled ones. Campbell et al. show that the HrpA protein in E. coli senses ribosome collisions and ...

The RNA helicase HrpA rescues collided ribosomes in E. coli: Molecular Cell www.cell.com/molecular-ce...

06.03.2025 18:47 — 👍 3    🔁 2    💬 0    📌 0

A wonderful meeting to share the latest developments on single-molecule research, network, and generate new ideas! Great invited speakers @sulianamanley.bsky.social @jungmannlab.bsky.social, David Rueda, Sebastian Diendl! Send us your Abstracts by *March 7th*!

04.03.2025 14:29 — 👍 5    🔁 1    💬 0    📌 0

Following the great success of the 2024 event, @ox.ac.uk and LUMICKS proudly present the second UK-Ireland symposium focusing on single-molecule research!

The abstract deadline, 7 March, is approaching fast. Secure a talk or poster by registering now > bit.ly/4gYPPpQ

24.02.2025 14:52 — 👍 4    🔁 3    💬 0    📌 1

So happy to see this AMR-related story from our 3-way collaboration!! Huge congrats to Alison + team, and thanks to @oxmartinschool.bsky.social for making it possible. Basic idea: deep "learning" ribosome distributions after antibiotic treatment rapidly classifies cells as resistant or not.

28.02.2025 19:01 — 👍 3    🔁 0    💬 0    📌 0

Wonderful achievement for Nic - what an amazing journey during the past few years for him! Dr Shiaelis, congratulations! Looking fwd to lots of success and discoveries in the years to come... Congrats to @nicolerobb.bsky.social as well, and big thanks to the examiners.

28.02.2025 18:54 — 👍 1    🔁 0    💬 0    📌 0

Base-modified nucleotides mediate immune signaling in bacteria Signaling from pathogen sensing to effector activation is a fundamental principle of cellular immunity. While cyclic (oligo)nucleotides have emerged as key signaling molecules, the existence of other ...

Fascinating...so much still to learn about bacterial mechanisms! Base-modified nucleotides mediate immune signaling in bacteria | Science www.science.org/doi/10.1126/...

21.02.2025 10:44 — 👍 1    🔁 0    💬 0    📌 0

Waiting for your abstracts by March 7! Join us with your recent stories for a "single-molecule festival" in mid-May... a lovely time to visit Oxford as well!

18.02.2025 18:21 — 👍 2    🔁 1    💬 0    📌 0

A DNA-PAINT protocol for the segment-specific detection of viral vRNPs. Virus particles are surface-immobilized, fixed, permeabilized and incubated with non-fluorescent barcoded probes, that bind to 20-50 different sequences on a viral RNA segment. All probes carry the same segment-specific oligonucleotide extension that is transiently bound by fluorescent imager strands. Several combinations of barcode extensions and imager strands can be used to sequentially to detect various gene segments in a single virus particle.

First BlueSky post + a breath of fresh air! Excited about our preprint on the packaging + structure of viral RNA segments in influenza virions: doi.org/10.1101/2025.... A saga from amazing Christof and Qing, and a great collaboration with @nicolerobb.bsky.social and @efodor.bsky.social.

17.02.2025 15:07 — 👍 12    🔁 3    💬 0    📌 0