Jordan Beach

LIM Domain Proteins link molecular and global tension by recognizing strained actin in adhesions Mechanotransduction is fundamental to cell signaling and depends on force-sensitive adhesion proteins. How these proteins differentiate and integrate their responses to tension remains an open questio...

Our new preprint is out! Led by @stefanosala89.bsky.social sky.social we investigate the difference between molecular tension sensing and global tension on the focal adhesion. Follow along for a thread of our findings:
www.biorxiv.org/content/10.1...

Interested in nuclear #mechanobiology? Join us for the first ever FASEB Science Research Conference on the Mechanobiology of the Nucleus #MBNSRC.
Find more information and register at: events.faseb.org/event/Mechan...
Submit abstracts by August 31, 2025. Please share and see you in October!

The PCM scaffold enables RNA localization to centrosomes As microtubule-organizing centers, centrosomes direct assembly of the bipolar mitotic spindle required for chromosome segregation and genome stability. Centrosome activity requires the dynamic assembl...

👏new paper👏 ! Our preprint is now accepted at MBoC @ascbiology.bsky.social

Congrats to co-1st authors Junnan (new PI at OSU!) and Weiyi (now a Yale grad student) and 🙏 to collaborators Melissa & Jordan @myosincity.bsky.social

Funded by NIH grants & NSF GRFP!
www.biorxiv.org/content/10.1...

Good times exploring Santiago, Chile with #neurocyto2025 rock stars @stephgupton.bsky.social @myosincity.bsky.social and Melissa Rolls

From a source at NIH:

“Right now NIH’s ability to buy things is dead. Nearly all people with the power to make an order — purchasing people — have been removed.
The NIH hospital can’t buy medicines, the labs can’t buy petri dishes. X-Ray machine breaks? Too bad.
Everything is stopped”

A headline reads: “U.S. Turned Away French Scientist Over Views on Trump Policies, France Says.” More text reads: “The French authorities said the academic had been traveling to a conference near Houston when border officials blocked his entry because of conversations found on his phone.”

The U.S. authorities denied entry to a French scientist and then deported him because his phone contained message exchanges with colleagues and friends in which he expressed his “personal opinion” on the Trump administration’s science policies, said the French government. nyti.ms/4iAZR2l

This is horrible to post, but I may as well post it. We are essentially shutting down research operations in my group, which is focused on treatments for pediatric brain cancer. I’m a well funded investigator, and there’s no choice. Science can’t function without the stability of NIH

Another household kept alive by American aid was that of Jennifer Inyaa, a 35-year-old single mom, and her 5-year-old son, Evan Anzoo, both of them H.I.V.-positive. Last month, after the aid shutdown, Inyaa became sick and died, and a week later Evan died as well, according to David Iraa Simon, a community health worker who assisted them. Decisions by billionaires in Washington quickly cost the lives of a mother and her son. "Many more children will die in the coming weeks," said Margret Amjuma, a health worker who confirmed the deaths of Peter and Achol.

Take a moment today to read about a few of the young children whom Trump and Musk killed by shutting down USAID. The blame for these deaths falls on them.

There will be hundreds of thousands more dead kids before their lethal crusade against foreign aid ends. www.nytimes.com/interactive/...

A 5 alarm fire for US governance and democracy and for you. 🚨

If Trump and Musk can do this criminal shredding of USAID w/ no consequence they will come for you next.

Democratic Senators and House members shld stop their days and head down to USAID w/ the Capitol Police and cameras and stop this.

It’s like letting your little sibling have a video game controller that isn’t plugged in.
“Go’head. Have yer lil study meetings.”

Without councils, there’s no point. Passing any CR without guaranteeing NIH money goes out the door is pointless.

NIH to ax grants on vaccine hesitancy, mRNA vaccines Move reflects vaccine skepticism of health secretary Robert F. Kennedy Jr.

The NIH is abruptly terminating at least 33 research grants for projects studying vaccine hesitancy. Projects studying mRNA vaccines may be next.
Important story by my colleague Sara Reardon in @science.org
🧪 #IDsky

French University to Fund American Scientists Who Fear Trump Censorship The program, called ‘safe place for science,’ offers American scientists funding to continue their research in France.

I wish my US colleagues and friends will have better times and I'm supporting them with all my heart. That said, there's also a possibility to come and be my colleague in beautiful Marseille!
www.404media.co/french-unive...

James Harrison, whose rare blood protected millions of babies, dies at 88 A rare antibody in his blood was used to create 3 million doses of an injection needed to protect newborns and prevent stillbirths.

Impressive!!! Still a ways to go to beat the legend

www.washingtonpost.com/obituaries/2...

shocking. I'm shocked that American customers will end up paying the tariffs. shocked.

Federal budget cuts threaten the work of neuroscientist with Martin County roots | Opinion Sarah Heilbronner is a proud product of Martin County schools. However, federal budget cuts threaten important work she's doing in brain research.

Neuroscientist Sarah Heilbronner is a proud product of Martin County schools in Florida 🌴. However, federal budget cuts threaten important work she's doing in brain research. 🧪🏠
@srheilbronner.bsky.social
www.tcpalm.com/story/opinio...

Chicago scientists reel from Trump funding cuts: 'We are just going to abandon all those discoveries' On Friday, scientists will leave their labs to protest cuts to research in Chicago and across the country.

Thanks to the Chicago Sun-Times for this amazing coverage of our Chicago team!

chicago.suntimes.com/columnists/2...

The institution of American science is on the front lines in the fight against fascism.

This is more than just indirect cost caps.

On March 7th, we stand for the freedom of thought, the power of knowledge, and, ultimately, democracy.

#standupforscience2025 #scienceforall

Please share widely!

OK folks--here is the answer. They are not simply removing programs because of their political biases--they are terminating existing NIH grants. Yours or mine could be next! 🧪

Please donate today! Your support is vital to sustain and grow Democracy Now! A daily independent global news hour with Amy Goodman & Juan González

Thank you to everyone who has contributed to our birthday fundraising campaign this month as we celebrate 29 years of independent journalism. If our work matters to you, please donate. Every dollar counts!

When performing surgery with a shotgun I’m not sure the order matters.

Ax falls on elite group of Ph.D.s training to lead U.S. public health labs Most of the fellows in CDC’s highly competitive Laboratory Leadership Service were fired last weekend

The CDC has an ultra-competitive 2-year program to train "the best of the best" to lead public health labs.
Most of the current class were terminated over the weekend. www.science.org/content/arti... (by @meredithwadman.bsky.social)

Very important to get this word out!

Federal Register hold makes ‘end run’ around court pause on NIH funding freeze NIH-related updates to the Federal Register, which are required for the scheduling of study sections and advisory councils, are on hold indefinitely, according to an email reviewed by <i>The Transmitt...

@ossoff.senate.gov @hankjohnson.house.gov

Emory researcher here 👋

By cancelling grant review and council sessions, the administration is in open defiance of court rulings to unfreeze NIH grants. They are playing games and impeding health research!

www.thetransmitter.org/funding/fede...

A post by Trump which says; He who saves his Country does not violate any Law

"I am the law."
Hitler, 1942

"There is no law but the law of the people & the people are me."
Gaddafi, 1975

"We have a constitution, but we must address the problems of the country first. The law is always behind when it comes to national survival."
Bashar Al-Assad, 2011

Trump, 2025:

a poster that says if life gives you lemon make lemonade on it ALT: a poster that says if life gives you lemon make lemonade on it

ATTENTION (PLEASE SHARE)

If anyone has or knows of any positions that might be appropriate for the NIH staff members who were terminated, please post the information in this thread.

There are lots of talented and accomplished people who may be looking for new opportunities.

Uncle Sam poster, he wants you to stand up for science.

Fighting to stop what's happening is profoundly patriotic, profoundly American. And We the People are mobilizing on March 7 to stand up for science. To be light in the darkness. @standupforscience.bsky.social

Seeing US science being vandalised is devastating 💔

For anyone in need of a new job: we have several postdoc and PhD positions in computational genomics, cancer epigenetics and immunology available here in Oxford, UK. We still care about DEI, offer 3y+ contracts and do cool science - get in touch!

Get in dorks, we're going protesting!

STAND UP FOR SCIENCE WITH US ON MARCH 7TH, 2025
WASHINGTON DC AND EVERY STATE CAPITOL

Because science is for everyone!

Find us at www.standupforscience2025.org

#standupforscience2025 #scienceforall #sciencenotsilence

Gutting USAID threatens billions of dollars for U.S. farms, businesses U.S. businesses that sold goods and services to USAID are in limbo, including American farms dealing in rice, wheat and soybeans.

US farmers sold $2 billion of food to USAID. Not any more.

- US farmers provided 41% of food delivered by USAID
- $340M of purchases/shipments are now paused. Over 680,000 tonnes.
- Food stranded in Houston
- Aid stopped in transit.

The world’s poor starving, food rotting & US farmers screwed.

NIH cuts billions of dollars in biomedical funding, effective immediately The move halts a large slice of money for most universities and research institutions virtually overnight, imperiling vital research in everything from cancer to heart disease.

NIH has cut billions of dollars in biomedical funding, effective immediately
The move halts a large slice of money for most universities and research institutions virtually overnight, imperiling vital research in everything from cancer to heart disease.

www.washingtonpost.com/health/2025/...