Tanveer Batth

You dun goofed!

Our latest #proteomics product to top off our Lys-C and Trypsin offerings. A high quality optimal premix of Lys-C and Trypsin that enables reproducible proteomic analysis! Make sure to follow @kplaps.bsky.social for more exciting news and updates!

#TeamMassSpec

Improving Precursor Selectivity in Data-Independent Acquisition Using Overlapping Windows - PubMed A major goal of proteomics research is the accurate and sensitive identification and quantification of a broad range of proteins within a sample. Data-independent acquisition (DIA) approaches that acquire MS/MS spectra independently of precursor information have been developed to overcome the reprod …

Check out the first author!
pubmed.ncbi.nlm.nih.gov/30671891/

Ehh yooo wtf!!

Looks like proteomics has hit the big time!

A small polymerase ribozyme that can synthesize itself and its complementary strand The emergence of a chemical system capable of self-replication and evolution is a critical event in the origin of life. RNA polymerase ribozymes can replicate RNA, but their large size and structural ...

Ooooh. Cool new paper on origins of life. A simple 45-nucleotide RNA molecule that can perfectly copy itself.

www.science.org/doi/10.1126/...

By 2028, all 4-character PDB IDs will be exhausted.

After that, all new entries will receive extended IDs: 12 characters total, formatted as pdb_ + 8 alphanumeric characters (pdb_1000axyz)

Test it from PDB Beta Archive

Read more: www.wwpdb.org/news/news?ye...

The Dolphin Head nebula in Canis Major constellation, photographed from my terrace

1/ The Dolphin Head (Sh2-308) is an emission nebula in the Canis Major region: a huge bubble created by material expelled by the star WR6, swept by its powerful stellar wind.
It’s also a target that drove me crazy for four years before I finally started to get a grip on it. ➡️

🔭
#Astrophotography

Closer

close enough?! (home made needle columns)

Me every single time i need to prepare a LCMS setup to run a couple of samples ...
#proteomics

Aside from the whisper network, how are #teammassspec finding out how much certain instrument models are down for (service delays, backordered parts, things breaking all the time, etc)?

From Croatia to MAHA: How an unapproved drug became the next hot peptide BPC-157 hasn't been approved by the FDA. But that hasn't stopped this buzzy drug from gaining traction – and attention from MAHA.

BPC-157 hasn't been approved by the FDA. But that hasn't stopped this buzzy drug from gaining traction – and attention from MAHA. www.statnews.com/2026/02/03/b...

Our recombinant, animal free, sustainable, artisanal 😁 Trypsin is here! High quality, high performance, drop in replacement for any existing #proteomics workflows.

Designed and produced in 🇩🇰🇪🇺

Zotero 8 is out, and we are very lucky to have such great open source software

Pervanadate-induced oxidation relieves autoinhibition of the protein tyrosine kinase SRC A widely used tyrosine phosphatase inhibitor also oxidizes and activates the tyrosine kinase SRC.

Pervanadate is more than just a phosphatase inhibitor!

Read our paper just published in #sciencesignaling showing that pervanadate oxidises and activates SRC kinase too.

Link: tinyurl.com/5ype7e2s

Thanks for the 'focus' by: @nshahlab.bsky.social tinyurl.com/54fcjds3

@babrahaminst.bsky.social

Single-cell proteomics is moving past descriptive snapshots to quantitative models of cellular regulation and biological mechanisms.

Come to #Boston this July to shape the next chapter and have your voice heard.

Abstract deadline: Apr 1, 2026.

single-cell.net/proteomics/s...

Trypsin is the workhorse of bottom-up #proteomics. But when was it first discovered? Lets try an emoji poll !

😇 1836
🤭 1876
😜 1897
🤑 1931

Reply with your guess!

Correct answer in the replies!

#TeamMassSpec

New publication alert! 📢

We collaborated with @jesperolsenlab.bsky.social to comprehensively characterize LysC homologs and study their impact on proteomic experiments.

For challenging samples, adding LysC can definitely make a difference in the data quality.

Congrats to all authors!

#proteomics

AutoPELSA: an automated sample preparation system for proteome-wide identification of target proteins of diverse ligands https://www.biorxiv.org/content/10.64898/2026.01.08.697612v1

To everyone who's supported us, bought from us, or just followed along to see what happens ... Thank you for a great year, you're the real MVPs!

2026 pipeline is looking spicy 🌶️ new products, big announcements I believe will push the field of #proteomics forward. Stay tuned.

Really curious to get peoples experience with using SCIEX instruments for bottom up proteomics 🤔🤔 Remember you can post anonymously so please share the price as well ! 😅

Comparative Analysis of Lysine-Specific Peptidases for Optimizing Proteomics Workflows pubs.acs.org/doi/10....

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#proteomics #prot-paper

When viewing the fake article in Google scholar on my university network, there is a link to access the article via my uni's library. That link sends me to a library page that makes fake article appear real... Turns out library page is made programmatically from info on Google scholar 🤦

Organelles do NOT have a single uniform pH.
And if you think they must, because “protons diffuse fast,” this paper is for you.
A thread on why that assumption is wrong; and what we found instead. 🧵 1/n

Holy cow the Zhou lab at UCLA is cooking with Isonet 2 - www.biorxiv.org/content/10.6...

Averaging-free direct visualization of ribosome translational state! #teamtomo #cryoet

What is "virtual" proteomics? 🥴

#AminoAcidAdvent Day 5: Threonine (Thr; T)

This essential amino acid was the last of "the 20" discovered, with no relation to the number 3 (sorry Jack White), but 1 of our 3 phosphomusketeers (TM). Dayhoff gave it the honors of T cause it was more frequent than the other T's... take that Y and W!

The Human Cell Line Phosphoproteome Atlas: A Deep Empirical Resource Revealing Kinase Activity Landscapes www.biorxiv.org/cont...

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#proteomics #prot-preprint