Max Renner

Thanks for the tip ☺️

Flu cases likely to 'spike' in coming weeks, warns health secretary Neil Gray says the rise in cases is a challenge and urges anyone able to get vaccinated to do so.

BBC News - Flu cases likely to 'spike' in coming weeks, warns health secretary - BBC News
www.bbc.co.uk/news/article...

Thanks, Lars :)

Great news and well deserved, Dan!!

Only a few days left to apply for this PhD opportunity in my lab! More details and how to apply at: www.findaphd.com/phds/project...

Warum auch in Deutschland die HIV-Infektionszahlen steigen Im vergangenen Jahr gab es in Deutschland mehr HIV-Neuinfektionen als im Jahr davor. Viele Infektionen werden erst im fortgeschrittenen Stadium erkannt - für Experten der Aidshilfe ein Alarmzeichen. V...

Heute ist Welt-AIDS-Tag. HIV hat seinen Schrecken als tödliche Erkrankung verloren. Trotz des medizinischen Fortschritts steigen jedoch die Neuinfektionen, auch hier in Deutschland, und Infektionen werden spät diagnostiziert. (1/2)

www.tagesschau.de/wissen/gesun...

MRC DiMeN Doctoral Training Partnership: Understanding molecular mechanisms of protein-primed genome replication in enteroviruses at University of York on FindAPhD.com PhD Project - MRC DiMeN Doctoral Training Partnership: Understanding molecular mechanisms of protein-primed genome replication in enteroviruses at University of York, listed on FindAPhD.com

🚨👇One week left to apply for this fully-funded PhD project to study RNA-protein complexes regulating enterovirus genome replication:

www.findaphd.com/phds/project...

What do you think?

Real SDS-PAGE gel or AI-generated ?

It’s been a while since I put together the Structural Virology starter pack, and I’m sure some new folks have joined Bluesky since then. There’s still plenty of space to fill, so if you’d like to be added to the list just let me know.

#virology #cryoEM

go.bsky.app/Qxv95BL

Scientific journals: we don’t want you using generative AI because it makes shit up.

Same journal: here is an AI summary or evaluation of this paper. This might be more useful than the actual abstract or paper that the authors freaking wrote

Same journal: AI cover art which makes no sense? Oooh!

A ubiquitin-like protein controls assembly of a bacterial type VIIb secretion system Cryo-EM structure reveals how a ubiquitin-like protein orchestrates assembly of a bacterial weapon system.

Our latest T7SS study is now out in Science Advances!
We solved the cryoEM structure of the T7SSb core unit (T7bCU) composed of YukB, YukC, and YukD from Bacillus subtilis, revealing how these components assemble within the secretion machinery.

www.science.org/doi/10.1126/...

Imagine we would have a pan-herpesvirus vaccine. How would it improve human health? Based on the last few years of data, I am thinking it would change a lot.

🧪For anyone interested in EBV in autoimmunity, I strongly urge you to read this incredible study by @shady-myounis.bsky.social, Bill Robinson, and @tobiaslanz.bsky.social. It is not only a scientific tour de force, it has a deeply provocative discussion that everyone in the field should consider 1/

Tired of knowing what you are looking for in your tomograms?
Why not try bluesky-less Frosina's new self-supervised algorithm for semantic segmentation and particle picking for #teamtomo (includes a new denoiser without the need for odd/even tomos)

Code is on GitHub if you want to try it out

This is misinformation by default, so if you're a journal and you use AI slop for your cover or your announcements, you're not scientific in any way and should be shamed mercilessly 🧪

Really fantastic to hear, congrats Ronnie 🤩

Truer words have not been spoken

We’re live!
The Department of Medical Biochemistry & Biophysics at @umeauniversitet.bsky.social explores life at the molecular level: infection and structural biology, gene expression, mitochondria, neurodegeneration & biophysics for climate change.
Follow for updates & collaboration!
#Biochemistry

I'd send it back and ask for validation reports at a minimum.

Withdrawing life-saving aid from developing countries and then demanding economically favourable conditions for restoring it would be bad enough, but the conditions and the approach also directly undermine international co-operation against future pandemics in favour of short-term national gain

Structural insights into cobalamin loading and reactivation of human methionine synthase Human methionine synthase (MTR) is an essential enzyme of one carbon metabolism. Consisting of a catalytic N-half and a cobalamin binding C-half, MTR utilises this intricate organometallic cofactor in...

I am excited to share our new preprint on our structural and biochemical analyses of human methionine synthase (MTR). This was the hard work of Douglas Ferreira who carried out this research as a significant part of his PhD. #CryoEM www.biorxiv.org/content/10.1...

Some still praise James Watson despite his racism. Same with colleagues who won’t condemn Elon Musk’s politics, hiding behind “scientists shouldn’t mix science and politics.”

Al Gore projected Florida winner

November 7th, 2000.

Thanks, mate 🤗

Godspeed!

Very happy to share our work on the Langya henipavirus nucleoprotein with everyone! 🥳

Check out the preprint to find more about how a serendipitous finding led us to this amazing story!

Proud co-supervisor of Rupesh @rupeshjayachandran.bsky.social, who has done an amazing job with this story in less than two years in Max's lab!

Thanks, Dan 🤗

Thanks Gytis, interesting 🤔! I don't think our structures explicitly explain this but we will give it some thought in light of the broader structural data available now.

Open and closed forms of assembled henipavirus nucleoprotein suggest structural basis of genome access Henipaviruses, such as Nipah virus, can cause deadly illness and constitute WHO blueprint priorities due to their pandemic potential. Their genomes are packaged within a nucleocapsid consisting of vir...

So proud of PhD student @rupeshjayachandran.bsky.social and postdoc Erwan Quignon for leading this research.

You can find the preprint here:

🔗 www.biorxiv.org/content/10.1...