Kevin Monahan

Please follow @insight-org.bsky.social on BlueSky and join us for insight2026.org in Singapore, abstract submission now live!

Please follow @insight-org.bsky.social on BlueSky and join us for insight2026.org in Singapore, abstract submission now live!

👋 Welcome to InSiGHT on BlueSky!

We are a global community of researchers, clinicians, and scientists dedicated to advancing the understanding, diagnosis, and management of hereditary GI cancers. Follow us for updates on scientific advances, clinical guidelines, and upcoming events. #InSiGHT

Abstract submission is now open for #Insight2026 ! Deadline 7th September #LynchSyndrome #Polyposis #EOCRC @soniakupfer.bsky.social @swatipatelmd.bsky.social @cgaigc.com @stmarksgenomics.bsky.social @plsdatabase.bsky.social

insight2026.org

Mainstreaming clinicians in colorectal and Gynae teams… think about this study!

St Mark's Frontiers 2025 Register now for our Annual Frontiers in Colorectal and Intestinal Disease Congress, from the 19th–21st November 2025.

Join us 19-21 November for a bigger and better St Mark's Frontiers in Colorectal Disease Meeting, in a beautiful venue in King's Cross London!
Extremely good value, with hybrid options @stmarkshospital.bsky.social

sayso.health/events/front...

St Mark's Frontiers 2025 Register now for our Annual Frontiers in Colorectal and Intestinal Disease Congress, from the 19th–21st November 2025.

Join us 19-21 November for a bigger and better St Mark's Frontiers in Colorectal Disease Meeting, in a beautiful venue in King's Cross London!
Extremely good value, with hybrid options @stmarkshospital.bsky.social

sayso.health/events/front...

Missed opportunities: Germline testing following tumor sequencing - PubMed In this cohort, 60 % of the eligible population by ESMO criteria did not receive GT, most commonly due to lack of referral (over 2/3 of patients). Further, 50 % of patients not referred for GT had mut...

Missed opportunities: Germline testing following tumor sequencing

pubmed.ncbi.nlm.nih.gov/40554180/

Great to meet up with Pam from Lynch Syndrome UK at BSG Live 2025 in Glasgow today! @thepoodoctor.bsky.social @lynchsyndromeuk.bsky.social @stmarksgenomics.bsky.social

On behalf of InSiGHT, we are delighted to welcome you to the #InSiGHT2026 meeting in Singapore, taking place from 4 – 7 March 2026 #LynchSyndrome #Polyposis @cgaigc.com @stmarksgenomics.bsky.social

insight2026.org

On behalf of InSiGHT, we are delighted to welcome you to the #InSiGHT2026 meeting in Singapore, taking place from 4 – 7 March 2026 #LynchSyndrome #Polyposis @cgaigc.com @stmarksgenomics.bsky.social

insight2026.org

Epithelial GREMLIN1 disrupts intestinal epithelial-mesenchymal crosstalk to induce a wnt-dependent ectopic stem cell niche through stromal remodelling - Nature Communications The authors show that aberrant epithelial GREM1 expression remodels intestinal stroma to form ectopic stem cell niches in mice. Anti-GREM1 reversed these changes, highlighting a potential strategy for...

Lovely new paper from @leedham-simon.bsky.social dissecting epithelium-microenvironment crosstalk through BMP & wnt signalling in the intestine. Inhibition of BMP antagonist GREM1 may forestall polyp formation in Hereditary Mixed Polyposis Syndrome (HMPS). www.nature.com/articles/s41...

In Our Scope of Practice: Genetic Risk Assessment and Testing for GI Cancers and Polyposis in Gastroenterology - @amergastroassn.bsky.social @soniakupfer.bsky.social www.gastrojournal.org/article/S001...

Optical assessment of advanced colorectal polyps survey and quiz Thank you for undertaking this survey and quiz. It should take 5-10 minutes to complete. All responses are completely anonymous. Please only respond once.

Are you an #endoscopist?
Interested in assessing & managing advanced #colonic #polyps?
Can we improve our #training in this?
@stmarkshospital.bsky.social
We are keen to hear your views. Please complete this short survey @esge-news.bsky.social

docs.google.com/forms/d/e/1F...

Led by our 2024 president, Bryson Katona, MD, PhD, our Executive Council developed a 3-year strategic plan to guide our society's future

We’re proud to share this as we mark our 30th anniversary.
Explore the plan 👉https://link.springer.com/article/10.1007/s10689-025-00473-9

#HereditaryGICancer

DETECT-2

If you are a from a #colorectalcancer #MDT and offering mainstream #genetic testing to your own patients then please consider joining Detect2 which may half your workload! We’re delighted to have recruited our first 3 patients… get in touch or click below for more www.detect-2.co.uk

Attitudes towards faecal immunochemical testing (FIT) for risk-stratified colonoscopy in people with #Lynchsyndrome #FIT4Lynch @bmj.com

bmjopengastro.bmj.com/content/12/1...

The BSL during Finland was sensational #Eurovision

Fantastic meeting about Lynch syndrome and hereditary CRC for MDTs, thanks to @britsocgastro.bsky.social @kevinmonahan.bsky.social and others

Fabulous day today at our @britsocgastro.bsky.social organised #LynchSyndrome event at #RCPLondon sold out, fabulous talks, interactive sessions and audience of clinicians who want to do their best for people with Lynch syndrome #BCSP @nhsmillion.bsky.social @rcphysicians.bsky.social

We are very excited about our @britsocgastro.bsky.social #LynchSyndrome event @rcphysicians.bsky.social next Wednesday… sold out but let me know if you want a place

…Like making ‘Conclave 2: The Return’

Primary care: the ‘linchpin’ in Lynch syndrome Hereditary cancer syndromes are inherited conditions which increase the lifetime risk of a person developing one or more cancers. These are complex conditions typically managed by a multidisciplinary ...

Primary care: the ‘linchpin’ in Lynch syndrome @bjgp.bsky.social

bjgp.org/content/75/7...

Our jobs We have vacancies in these professions, sectors, and interests

Please join our incredible team as an Advanced Nurse Practitioner in Inherited Cancer Syndromes - closing date this Monday 5th May! Provide lifelong care to our very special patient group #LynchSyndrome #FAP #Genomics #polyposis
@stmarkshospital.bsky.social
lnwh.nhs.uk/jobs/

One hundred years of the St Mark’s hospital polyposis registry - Familial Cancer The St Mark’s Hospital Polyposis Registry was founded in 1924, the first such unit in the world. This paper documents the development of the unit over the subsequent 100 years, which was inextricably ...

One hundred years of the St Mark’s hospital polyposis registry @stmarksgenomics.bsky.social @lnwh.bsky.social
link.springer.com/article/10.1...

Promising early safety and immunogenicity data from the Nous-209 Lynch Syndrome vaccine presented at AACR this month aacrjournals.org/cancerres/ar...

How the United States became a science superpower — and how quickly it could crumble US global dominance in science was no accident, but a product of a far-seeing partnership between public and private sectors to boost innovation and economic growth.

Could or is crumbling? @nature.com
www.nature.com/articles/d41...

A Full-Body MRI Scan Could Save Your Life. Or Ruin It The celebrity-endorsed scan might save your life and detect a hidden cancer. Or it might start a spiral of anxiety.

On Full-Body MRI
“The odds that you’re going to be hurt are higher than the odds you’re going to be helped”
time.com/7275819/shou...

This is Ripley. He was nervous about taking the stairs. May have panicked a bit. 12/10

Guidelines for Familial Adenomatous Polyposis (FAP): challenges in defining clinical management for a rare disease - Familial Cancer Recent updated management guidelines for Familial Adenomatous Polyposis (FAP) have been published by professional bodies internationally. These recommendations reflect the diverse needs and capabiliti...

Guidelines for Familial Adenomatous Polyposis (FAP): challenges in defining clinical management for a rare disease

link.springer.com/article/10.1...