GenSCAPE (aka Raghavan) Lab 🧬

6/n This study could not have been possible without the incredible support of the local communities in Himachal Pradesh, our archaeological collaborators, and every co-author who made this work possible - Thank you all! 🥳

5/n This study provides first insights into the admixture dynamics and adaptive histories at the northern frontier of the Himalayas.

4/n Some present-day individuals also show admixture with lowland South Asian ancestry, highlighting a dynamic history of genetic continuity and admixture in this region of the Himalayas.

3/n Our results show that ancient and present-day individuals from the region largely carry Tibetan ancestry (source of high-altitude adaptive introgression signal), with substantial Steppe-related ancestry observed in individuals dating from ~1,300 years ago to present times.

2/n We generated genome-wide data from 7 ancient (~2300–100 years old) and 10 present-day individuals from the northern Indian Himalayas, and a ~3370-year-old individual from the Central Himalayas in Nepal. 🦴🧬

Dynamic human admixture histories over the past ~1300 years at the northern Himalayan frontier Ancient and present-day human genomes shed light on ~1300 years of genetic admixture and continuity in the northern Himalayas.

1/n Delighted to share our newly published work in Science Advances, investigating human genetic histories at the northern frontier of the Himalayas 🧬🏔️:
www.science.org/doi/10.1126/...

Come and check out @jaurban2204.bsky.social's PhD project now live in Current Biology!!!

The Genscape Lab at UChicago is now live on BlueSky!