Guillermo Posadas H.

Summer festival dancing

Nice afternoon at the local summer festival 🪭☀️

Explosion on Saitama University lab during experiments, fortunately it seems victims had only minor injuries.
I can already see the e-mails that will come from the safety management office of my university...

May work bringing back Japanese researchers from overseas labs, but foreigners likely have better options in other countries.

This month Netflix made available the series "99.9 criminal lawyer" and this series of instructional videos is what I keep thinking about every time Katagiri Jin is on the screen.

If we trust genetic engineering to save a child from leukemia, why reject it when it could save a child from blindness, malnutrition, or death?

We cure cancer with genetic engineering but ban it on the farm.

Celebrating one but demonizing the other fuels disinformation that costs lives.

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Why Lyme disease and other tick-borne conditions are on the rise

Ticks are spreading globally and bringing familiar conditions such as Lyme disease with them, as well as totally new ones. Now research is revealing how to prevent and treat the diseases they carry.

A blueprint for the batmobile.

Your genome is not a blueprint. A thread about misleading metaphors in science communication. 🧬🧪 1/n

I should not have seen this video at work, can't stop laughing.

50 days for the annual meeting of the Japan Society of Gene and Cell Therapy! still swamped on things to do but looking forward to it.
square.umin.ac.jp/jsgct2025/en...

I have always liked this example to justify giving up on counters
www.ytv.co.jp/nihongo/revi...

⚠️ Discovery of a new mode of viral transmission:

Deltaviruses spread through a viral Trojan Horse !

These viral satellites that do not encode their own glycoproteins, are in fact physically encapsulated within their helper virus particles!

www.biorxiv.org/content/10.1...

A thread 1/14

解説の掛布 - 新・なんJ用語集 Wiki* ５ちゃんねる「なんでも実況J」（なんJ）やその他関連板で使われている用語を解説・まとめるwikiです。

According to this
wikiwiki.jp/livejupiter/...

its a play of words between

解説の掛布 (Kaisetsu no kakefu) "a commentary by Kakefu" (a famous baseball player)
and
風説の流布 (fuusetsu no rofu) "spreading false rumours"
Usually to point out some insensitive bait-and-switch thing being published.

I consider this a positive development.

Cherry tree blossoming in front of a building

Time-lapse of the Cherry blossom in the campus on the last week, full bloom just in time for the Hanami party tomorrow🌸#花見

Three more months until the annual meeting of the Japanese Society of Gene and Cell Therapy in Tokyo.
Regular abstract submission already closed, but there is still a chance to submit "Late breaking abstracts" for poster presentation until the end of April!

square.umin.ac.jp/jsgct2025/en...

Blood donation day at the hospital. I apparently accumulated some points and got a small notebook as a prize 🩸🅾️
#献血

I think it is perfectly valid to think of culture as a type of infection, after all there are beneficial parasitic relationships as well (like bacteriophages or probiotics)

The only thing I recognize about the whole thing is the idea of adapting the "culture" part of protoculture from "civilization-culture" to "plant-culture" in order to make it a power source and have an excuse to link the series.

Wow, I can't remember snow this late in March in all my years living in Tokyo ❄️🗼

Lungfish xkcd.com/3064

Suddenly spring begins on campus...

Unbelievable news.

Pancreatic is one of the deadliest cancers.

New paper shows personalized mRNA vaccines can induce durable T cells that attack pancreatic cancer, with 75% of patients cancer free at three years—far, far better than standard of care.

www.nature.com/articles/s41...

Extraordinary!
Makes it easier to be optimistic about these kind of interventions.

The downside is: Some outlets actively promote misinformation that contradicts the content of the articles, for example by publishing alongside comments that say the opposite. It is hard to see an article as positive when it is followed by dozens of comments saying everything written is a lie.

I guess this weekend was not the best time to watch the Bell riots episodes of DS9...

The Indigenous People of North America have decided to go back to calling the Gulf of Mexico, “Chalchiuhtlicueyecatl”. It is what the Nahuatl People originally called it as it is the domain of the goddess Chalchiuhtlicue, who is assoc w/water bodies, including the Gulf of Mexico.

I really like the Research Findings Presentation meeting of my institute, which is leading research in several very interesting areas from organoid transplantation to oncolytic vaccines. It really turns on the "motivation switch", maybe I can present something like that next year?

Apparently the world needs more punishment...

The New England Journal of Medicine CRISPR-Based Therapy for Hereditary Angioedema A PLAIN LANGUAGE SUMMARY Illustration of a patient with hereditary angioedema and NTLA-2002, a nonviral gene-editing therapy based on CRISPRCas9, for treatment. Read the full Plain Language Summary at NEJM.org.

In a new phase 2 trial, researchers evaluated the efficacy of a gene-editing therapy, NTLA-2002, in preventing angioedema attacks in patients with hereditary angioedema. Full trial results and Plain Language Summary: nej.md/4heR7hT

#MedSky #Oncology

In vivo engineering of murine T cells using the evolved adeno-associated virus variant Ark313 Genetic engineering of T cells in mouse models is essential for investigating immune mechanisms. We aimed to develop an approach to manipulate T cells…

🚨New paper alert! 🚨 Our latest work in
@cp-immunity.bsky.social shows that Ark313, an evolved AAV variant enables in vivo genetic engineering of murine T cells! 🧵👇

sciencedirect.com/science/arti...