Maire Röder

SPP1 is required for maintaining mesenchymal cell fate in pancreatic cancer - Nature Mutual paracrine regulation of the cytokines GREM1 and SPP1 mediate mesenchymal and epithelial cell fate in pancreatic cancer.

Nature research paper: SPP1 is required for maintaining mesenchymal cell fate in pancreatic cancer

go.nature.com/3VuMFSC

Just one of countless crimes against humanity. This man had two young children. Simply devastating 💔 #freepalestine

New neurons are generated throughout adult life in the adult neurogenic niche in the hippocampus through activation of reversibly quiescent neural stem cells (NSCs). The cover highlights DCX+ immature neurons (blue) in the hippocampal dentate gyrus of a conditional mutant mouse for Sox5, with recombined Sox5 deficient cells in magenta. Medina-Menéndez et al. report that Sox5 is required to control the correct establishment of quiescence during the first postnatal weeks of dentate gyrus development, which is essential for establishing long-lasting adult neurogenesis. https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002654

Ever wondered how adult #NeuralStemCells develop and acquire their lifelong potential?
Excited to share our latest work on the origin of #AdultNeurogenesis by Cris Medina
@paulatiradom.bsky.social Lingling Li & @pilar-rguezm.bsky.social now in @plosbiology.org🧪🧠
@institutocajal.bsky.social
👇🧵

The Sympathizer by Viet Thanh Nguyen. Anything by Amor Towles, Blake Crouch, Jennifer Egan. These are some that spring to mind instantly!

Thank you past Maire for being a big neuro nerd, helpful for my first job!

My #booksky this week is Butter by Asako Yuzuki- an interesting choice for someone who's been plant based since 2015! The very graphic descriptions of food haven't given me bloodlust yet... First impression was pretty easy reading, but increasingly there are feminist undertones: always welcome here!

Very glad I stuck with it, kept getting better and better! Highly recommend!

Deutsches Technikmuseum, Berlin. Making a beeline for the plane and computer exhibitions 🤩

My second #booksky is a holiday edition and is Caledonian Road by Andrew O'Hagan. Mayflies was great and a nice window into a lifelong male friendship, prompting me to try this. At first the characters seemed caricature-like, lacking nuance but as the plot thickens it's growing on me.

The deadly old men who rule half the world In a draining digital age of new problems and new tech, the planet’s most powerful leaders are all in their 70s – and increasingly at war with reality

Six men in their 70s – Donald Trump, Xi Jinping, Narendra Modi, Recep Erdoğan, Benjamin Netanyahu, and Vladimir Putin – control 40% of the world population, 50% of GDP, and 60% of the world’s military.

I profiled this “old guard” and what they’re doing to the world.

I’ve said it before, I’ll say it again, and I know I speak for millions of people up and down this country:

We are all Palestine Action 🇵🇸

Seen in Hamburg

Range extender mediates long-distance enhancer activity - Nature The REX element is associated with long-range enhancer–promoter interactions.

Our paper describing the Range Extender element which is required and sufficient for long-range enhancer activation at the Shh locus is now available at @nature.com. Congrats to @gracebower.bsky.social who led the study. Below is a brief summary of the main findings www.nature.com/articles/s41... 1/

Cancer cells get power boost by stealing mitochondria from nerves Nature - The theft probably helps the cells to spread around the body, and preventing it could provide a path to treatment, researchers say.

Cancer cells turbocharge themselves by stealing the energy-producing units from neurons in tumours

https://go.nature.com/4nnVyda

Amazing work from a very smart ex labmate of mine 🌟 congratulations Anna

#climbsky do you copy? My challenge to myself is to make a little #boulderoftheweek vid when possible and keep it going through FY1. If I could prescribe climbing as a public mental and physical health strategy I would. This #fail was so close yet so far, I blame 30 degrees. #docsonblocs

10 years, 3 degrees, a husband, and a child later. You can call me Dr Dr 😋 that pint was so needed after a ceremony in 33 degree heat

Greta Thunberg, arriving back in Europe after her abduction by Israel in international waters, explains in 40 seconds why western governments are colluding in genocide:

Amazing and also belongs on r/oddlysatisfying 😌

A year of stem cell and developmental biology In recent years, the field of stem cell and developmental biology has seen remarkable breakthroughs that have deepened our understanding of how organisms ...

www.nature.com/collections/...

My first #booksky is my latest read: Orbital by Samantha Harvey. One of the best of the past couple of years. It's like a painting with the English language as the medium. Truly uplifting and captures so much of the human experience. Similar recs very welcome #orbital #samanthaharvey

Books are my self-care so ahead of starting FY1 I'll make weekly #booksky posts on Sundays. I'll share current reads and old favourites across fiction, sci-fi, and popular science. I used to use X for papers and IG for book & climbing content but both have become insufferable cesspools so here I am!

Who could’ve guessed that ketamine could cause a Twitter meltdown?

The diverse roles of the circadian clock in cancer - Nature Cancer Masri and colleagues review the latest studies on the influence of circadian rhythms in cancer biology, discussing possible connections between chronobiology and cancer prevention and treatment.

📣Don't miss this recent REVIEW published at Nature Cancer:

'The diverse roles of the circadian clock in cancer'

✏️By Nicholas Pannunzio, Selma Masri @ masrilab.bsky.social and colleagues

🔗 www.nature.com/articles/s43...

Flybase 😢 🪰

For some happy brain chemicals, try my friend's polytris and see whether you can beat my score www.jensroesner.com/games//polyt...

Cancer more deadly when tumours lack Y chromosomes — and the loss could be contagious Losing the Y chromosome seems to make cancer cells more aggressive in men and the phenomenon may even spread between cells.

Losing the Y chromosome seems to make cancer cells more aggressive in men and the phenomenon may even spread between cells

https://go.nature.com/3Zh7bs7

Brain drugs can now cross the once impenetrable blood–brain barrier Nature - New technologies to shuttle drugs into the brain are showing promise in Alzheimer’s disease, cancer and more.

Brain shuttles - new technologies to traverse the blood-brain barrier - are showing promise in Alzheimer's, cancer, and more

https://go.nature.com/3T5WuF7

This is an amazing piece of writing- open, honest, moving. Well worth reading from start to finish.

Engaged in a sportier kind of geekery this afternoon in the exercise physiology lab as a study participant. Despite gaining a few kgs over exam period my VO2 max is higher 🫀🫁💪🏼