..so, as an Interested Amateur, can I assume that the current expert thinking is that most (all?) "complex traits" are highly polygenic (and the genes pleiotropic), making most of these targeted genetic engineering claims unworkable fantasies?
19.12.2024 20:07 β π 1 π 0 π¬ 1 π 0
The deCODE connection made me suspect as much. ;-) Some of my old (ex-CCP Games) colleagues did a stint there too, although I think they've since moved on to other things.
19.12.2024 20:04 β π 1 π 0 π¬ 0 π 0
..oh, damn, I see your earlier link now -- it hasn't come through originally. Sorry!
19.12.2024 19:54 β π 1 π 0 π¬ 1 π 0
I saw this original claim, and was wondering about it. A brief search suggested that it *might* be more solid than other early CGS results, but I don't know.
But do you know the literature well enough, as a pro, that I should just dismiss it?
19.12.2024 19:53 β π 1 π 0 π¬ 1 π 0
..originally refugees/escapees/outlaws from Norway in the 9th century (and some abductees from Ireland eventually) then, more recently, people like me escaping from the UK!
It's quite civilised now, and the climate's not *quite* as bad as you might expect, although the current 4hr days are not fun!
19.12.2024 19:16 β π 2 π 1 π¬ 1 π 0
I live in Reykjavik (am originally from the UK), and it seems that the place changed radically during and after WWII (in terms of economic development etc.) as a consequence of British and US troops setting up bases here, and later subsiding development post-war.
19.12.2024 19:09 β π 3 π 0 π¬ 1 π 0
Which app is that?
19.12.2024 10:07 β π 2 π 0 π¬ 0 π 0
Yep. It's terrific.
19.12.2024 02:17 β π 1 π 0 π¬ 0 π 0
YouTube video by Nick Lutsko
Nick Lutsko - Punchline (Official Music Video)
The latest from Nick "Big Nick" Lutsko. @nicklutsko.bsky.social
And it's typically excellent: an interesting mixture of bleakness and hope.
Maybe of interest to @funhouseradio.bsky.social ?
19.12.2024 02:14 β π 20 π 4 π¬ 0 π 0
#Writer, #coder. Code C64 games in my spare time. Released my #BrileyWitch #C64 #RPG via http://itch.io. Also owner of 3 cats.
https://sarahjaneavory.itch.io/
Blog: http://www.breakintoprogram.co.uk
YouTube: https://www.youtube.com/BreakIntoProgram
Ko-fi: https://ko-fi.com/breakintoprogram
Software developer & electronics dabbler. Restoring & programming vintage computers from Acorn Atom to ZX81.
Science integrity consultant and crowdfunded volunteer, PhD.
Ex-Stanford University. Maddox Prize/Einstein F Award winner
NL/USA/SFO.
#ImageForensics
@MicrobiomDigest on X.
Blog: ScienceIntegrityDigest.com
Support me: https://www.patreon.com/elisabethbik
A podcast dedicated to the 1967 tv show βThe Prisonerβ hosted by Cai Ross and Chris Bainbridge. https://linktr.ee/freeforallpod
Created improv videogame comedy The Dark Room. Occasionally viral. Bit of crowdwork. Dirty electric ukulele. My 2025 UK stand-up tour βJohn Robertson Plays With The Audienceβ starts Oct 5th! ALL SHOWS: thejohnrobertson.com/livedates
Bioinformatics Scientist / Next Generation Sequencing, Single Cell and Spatial Biology, Next Generation Proteomics, Liquid Biopsy, SynBio, Compute Acceleration in biotech // http://albertvilella.substack.com
Husband, dad, veteran, writer, and proud Midwesterner. 19th US Secretary of Transportation and former Mayor of South Bend.
Godless polyamorous author & speaker. Philosophistorian. Longform blogger. Destroyer of bad epistemologies. Drinker of whiskey & sensible wine. You can find all things me at richardcarrier.info (books, classes, blog).
Prof of EBM @UniOxford, author, Bad Science person, more... I run http://bennett.ox.ac.uk making tools+papers from data http://OpenSAFELY.org http://OpenPrescribing.net
Research and data to make progress against the worldβs largest problems. Based out of Oxford University (@ox.ac.uk), founded by @maxroser.bsky.social.
Professional game developer
Walldoffstudios.com
P(A|B) = [P(A)*P(B|A)]/P(B), all the rest is commentary. Click to read Astral Codex Ten, by Scott Alexander, a [β¦] [bridged from astralcodexten.com on the web: https://fed.brid.gy/web/astralcodexten.com ]
Senior Lecturer in Statistical Genetics at KCL.
Group GitHub: https://github.com/ColemanResearchGroup/GroupInfoPublic. Views own. He/Him
An open database of polygenic scores and the relevant metadata required for accurate application and evaluation
https://www.pgscatalog.org/
Linguist, cognitive neuroscientist and wannabe geneticist. Associate Professor at University of Iceland. Views are my own. https://uni.hi.is/rosas and https://english.hi.is/staff/rosas
Evolutionary geneticist, ex-media scientist. Trees of humans, trees of life, all things biology.
Genetics. Evolution. History
https://www.razibkhan.com
https://www.razib.com
Professor of Ancient Genomics and Evolution, GEE, University College London.
www.burbanolab.org
Genomics, Machine Learning, Statistics, Big Data and Football (Soccer, GGMU)
assistant professor at ucsf interested in genetics, statistics, etcβ¦
jeffspence.github.io