Integration Initiative: Sex, Aging, Genomics, and Evolution

Why male embryos grow faster: Study reveals genetic clues | Cornell Chronicle Cornell researchers have uncovered the genetic triggers that cause male and female bovine embryos to develop differently, as early as seven to eight days after fertilization.

Check out this article in Cornell Chronicle written about our new paper "Sex-biased transcriptome in in vitro produced bovine early embryos": news.cornell.edu/stories/2025...

04.09.2025 16:01 — 👍 0    🔁 0    💬 0    📌 0

Sex-biased transcriptome in in vitro produced bovine early embryos - Cell & Bioscience Background Morphologic sex differences between males and females typically emerge after the primordial germ cell migration and gonad formation, although sex is determined at fertilization based on chr...

Check out our new paper! "Sex-biased transcriptome in in vitro produced bovine early embryos" published in Cell & Bioscience. Read here:
cellandbioscience.biomedcentral.com/articles/10....

04.09.2025 15:44 — 👍 0    🔁 0    💬 0    📌 0

This past week, IISAGE scientists from labs nationwide gathered at Brown University in Rhode Island for our annual NSF conference. It was a highly productive meeting where we shared updates, discussed our scientific progress, and made significant plans for the future of this amazing grant! 🪰 🔬 🧪

06.08.2025 15:07 — 👍 0    🔁 0    💬 0    📌 0

Our IISAGE trainees made a big presence at the Evolution 2025 conference this past week in Athens, GA, where they presented their incredible work on sex-biased aging within the animal kingdom! #evolution2025 🧬🪰🔬

27.06.2025 14:09 — 👍 0    🔁 0    💬 0    📌 0

DNA Methylation Dynamics Reflect Sex and Status Differences in Mortality Rates in a Polygynous Bat Males of polygynous mammals often do not live as long as females and, in some cases, exhibit evidence of earlier senescence. Patterns of DNA methylation (DNAm) have recently been used to predict chro...

Check out our new paper! "DNA Methylation Dynamics Reflect Sex and Status Differences in Mortality Rates in a Polygynous Bat" published in Molecular Ecology. Read here: onlinelibrary.wiley.com/doi/10.1111/...

31.03.2025 13:38 — 👍 0    🔁 0    💬 0    📌 0

IISAGE makes a presence at the 66th Annual Drosophila Research Conference! Our team of fly scientists showcased their work to the public, engaging the science community with recent discoveries regarding aging in the Drosophila species! 🪰 #Dros25

25.03.2025 15:24 — 👍 2    🔁 0    💬 0    📌 0

TWO WEEKS AWAY - March 20th from 12-1pm ET: Join AFAR for a free #webinar exploring #biotech innovations that are driving #regenerativemedicine for longevity.
Featuring leaders from LyGenesis, Morphoceuticals, Mayo Clinic, & UCLA.
Learn more & RSVP here: bit.ly/41l5slH

06.03.2025 16:00 — 👍 0    🔁 1    💬 0    📌 0

Home Revealing the Mechanisms of Sex Differences in Aging. The Integration Initiative: Sex, Aging, Genomics, and Evolution (IISAGE) is an NSF-funded Biological Integration Institute aimed at understanding ...

JOB OPENING: We are seeking a Bioinformatics Research Analyst to join the Integration Initiative: Sex, Aging, Genomics, and Evolution (IISAGE; www.iisage.org). Explore details and apply here: cornell.wd1.myworkdayjobs.com/CornellCaree...

17.02.2025 15:31 — 👍 1    🔁 0    💬 0    📌 0

Check out our paper -> "TimeFlies: an snRNA-seq aging clock for the fruit fly head sheds light on sex-biased aging" currently in review at Scientific Reports doi.org/10.1101/2024...

29.01.2025 15:28 — 👍 0    🔁 0    💬 0    📌 0

Check out Dr. Wilkinson's team in action, doing fieldwork on big brown bats in Trinidad! 🦇🌿 #BatResearch #Fieldwork #AgingResearch #IISAGE

21.01.2025 15:20 — 👍 0    🔁 0    💬 0    📌 0

Great presentation from our institute director Dr. Nicole Riddle at PAG32! 🧬 #PAG2025 #AgingResearch

16.01.2025 16:42 — 👍 1    🔁 0    💬 0    📌 0

IISAGE hosted a workshop at the Plant and Animal Genome Conference (PAG) in San Diego, CA! The session, "Genomics and Epigenomics of Aging," highlighted recent breakthroughs in aging research across species. Big thanks to all the amazing speakers! #Genomics #AgingResearch #PAG2025

16.01.2025 16:39 — 👍 2    🔁 0    💬 0    📌 0

Another packed house this morning at our 10th seminar in our Live Better Longer Community Seminar series. Today research on aging is the most interrogated field in all of the life sciences. Dr Verdin is addressing what’s next for the field, and how soon will we get there.

15.01.2025 19:49 — 👍 3    🔁 1    💬 0    📌 0

IISAGE is off to a strong start in 2025! Our team joined UAB's Biology Dept. at the SICB meeting, connecting with 150+ students and showcasing trainees' research to share IISAGE discoveries with the public! #SICB2025 #Research #IISAGE
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16.01.2025 15:09 — 👍 1    🔁 0    💬 0    📌 0

Redirecting

Check out our paper -> "Hallmarks of Aging: A User’s Guide for Comparative Biologists" in Ageing Research Reviews: doi.org/10.1016/j.ar...

12.12.2024 19:29 — 👍 0    🔁 0    💬 0    📌 0

Hey @iisage.bsky.social , can we try to do all 12 of these as part of the strategic plan?

22.11.2024 15:16 — 👍 1    🔁 1    💬 0    📌 0

Our review paper "Hallmarks of Aging: A User’s Guide for Comparative Biologists" was just accepted for publication in Ageing Research Reviews. Congrats to all the authors!

03.12.2024 15:38 — 👍 0    🔁 0    💬 0    📌 0