Diego A. Pacheco Pinedo

Specialized parallel pathways for adaptive control of visual object pursuit To pursue a moving visual object, the brain must generate motor commands that continuously steer the object to the center of the visual field via feedback. The gain of this control loop is flexible, y...

Delighted to share an updated pre-print on how adaptive control in visual pursuit is implemented at the circuit level. New behavior and neuronal data in females (!) shows how two AOTU pathways are key elements in both sexes.

Check it out on @biorxiv-neursci.bsky.social :
doi.org/10.1101/2025...

How is the nervous system organized to coordinate behavior? To approach this massive question, a team led by @asbates.bsky.social, @jasper-tms.bsky.social, @mindyisminsu.bsky.social, & Helen Yang present the BANC: a Brain and Nerve Cord connectome.

Preprint: doi.org/10.1101/2025...

🧪#Neuroskyence

Thrilled to have been part of this amazing team and to get an early, hands-on look at such a unique and rich full-brain and cord dataset. Congratulations to everyone involved in this large collaborative effort!

Specialized parallel pathways for adaptive control of visual object pursuit To pursue an unpredictably moving visual object, the brain must generate motor commands that continuously steer the object to the midline of the visual field via feedback. Behavior implies that visual...

Many animals use "adaptive control" to pursue moving objects, relying on flexible feedback loops to adjust their movement gain over time. But how do neural circuits actually implement this?

Here, we show how adaptive control in Drosophila pursuit involves two specialized parallel feedback loops.