Rui Gonçalo Martinho's Avatar

Rui Gonçalo Martinho

@martinholab.bsky.social

Our AIM is to understand the way germ cells segregate from the soma and differentiate into functional gametes.

538 Followers  |  1,844 Following  |  152 Posts  |  Joined: 21.08.2023  |  2.3223

Latest posts by martinholab.bsky.social on Bluesky

Brandeis University, Biology Department Job #AJO30961, Assistant Professor in Biology and Neuroscience Program, Biology Department, Brandeis University, Waltham, Massachusetts, US

TT faculty job opening in #Neuroscience!
We are looking for a colleague to join us in our fantastic Biology Department and Neuroscience Program at Brandeis. We are a group of *very* collaborative, supportive, and productive scientists (& humans!) so please apply
academicjobsonline.org/ajo/jobs/30961

22.10.2025 23:28 — 👍 85    🔁 103    💬 1    📌 3
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🪰 A new ‘Eyemap’ developed by a team led by Arthur Zhao & @michaelreiser.bsky.social reveals how visual information detected by the fly’s eye shows up in neurons deep in the brain. Remarkably, the eye’s shape determines how flies see motion.👁️
🔗 hhmi.news/4kSZjou

23.07.2025 15:18 — 👍 102    🔁 22    💬 4    📌 3
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Most migratory birds are gone but its still a gorgeous place do visit - Boquilobo Bog Natural Reserve.

09.11.2025 11:45 — 👍 0    🔁 0    💬 0    📌 0
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Not today, parasitic #wasps!✋🚫

#Stinkbugs use a fungus-carrying organ on their hind legs to coat their eggs in #fungi🍄🦵

This provides a physical defense against #parasitic wasp oviposition🛡️

www.science.org/doi/10.1126/...

22.10.2025 17:12 — 👍 12    🔁 6    💬 0    📌 0
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Full text in links

Full text in links

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Faculty positions in animal morphogenesis that may be filled at the Assistant or Associate Professor level in one of my favorite Departments" Cell and Systems Biology at the University of Toronto. 1/n
jobs.utoronto.ca/job/Toronto-...
jobs.utoronto.ca/job/Toronto-...

06.10.2025 18:09 — 👍 37    🔁 34    💬 2    📌 1
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Are you interested in a PhD in the area of "Mechanisms of translational control during embryogenesis?" Apply now for a PhD @mpi-cbg.de! Overview of all participating RGLs: imprs.mpi-cbg.de/5761/researc...

02.10.2025 14:24 — 👍 23    🔁 14    💬 1    📌 2
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#FossilFriday ‘Black Beauty’, one of the smallest-known specimens of Tyrannosaurus rex, displayed at The Royal Tyrell Museum in Calgary, Alberta.
wp.me/p3ihHu-1MX

03.10.2025 21:51 — 👍 76    🔁 23    💬 4    📌 1

Quick Drosophila question: I’m planning to integrate a construct on the second chromosome but would like to avoid the attP40 landing site. Any suggestion for a good alternative attP site on chromosome II? It’s for a skeletal-muscle–related project.
Thanks! 🙂
Rui

30.09.2025 18:34 — 👍 3    🔁 5    💬 1    📌 1
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Linear covariation between germline and somatic mutation rates across ciliates and mammals Wang et al. estimate the somatic mutation rate in a ciliate, which contains germline and somatic genomes in the same cell. They discover a linear correlation between per-year germline and somatic muta...

www.cell.com/current-biol...

26.09.2025 17:59 — 👍 2    🔁 0    💬 1    📌 0
Nautiloids (pictured)—a lineage of ancient, externally shelled cephalopods—once dominated our oceans, but today, these living fossils are threatened and in need of protection from over-exploitation.

Nautiloids (pictured)—a lineage of ancient, externally shelled cephalopods—once dominated our oceans, but today, these living fossils are threatened and in need of protection from over-exploitation.

Our latest issue is out!👇
www.cell.com/current-biol...

On the cover: Nautilus ≈ 🐙+🐚

(Maybe — like the Nautilus — our journal is a living fossil, believing in the interest and inspiration our readers might draw from the diversity of biological systems, questions and approaches we try to feature🙏 )

22.09.2025 17:28 — 👍 40    🔁 7    💬 0    📌 2
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Epigenetic relay: Polycomb-directed DNA methylation in mammalian development In mammals, repression of germline-specific gene expression is essential for preserving somatic cell identity and preventing disease. Germline gene silencing is often dependent on the presence of prom...

Very excited to share an excellent review from @teresa-urli.bsky.social, published one week before her PhD defense! We did a deep dive into the fascinating biology of the variant Polycomb complex, PRC1.6 (1/5) journals.plos.org/plosgenetics...

15.09.2025 19:03 — 👍 91    🔁 35    💬 3    📌 2

“Proposals by *** outgoing *** country”… ?! We need feedback from someone that really knows about this topic :)

14.09.2025 16:41 — 👍 1    🔁 0    💬 1    📌 0
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Chart from last year... No big change in % of US applicants, or? . marie-sklodowska-curie-actions.ec.europa.eu/news/msca-po...

14.09.2025 13:49 — 👍 2    🔁 2    💬 1    📌 0

no - because this would have reduced the % of candidates from the US, right?

14.09.2025 15:28 — 👍 0    🔁 0    💬 1    📌 0

📰 New paper alert!

In a collaborative project with the lab of Clemens Plaschka at the IMP, the lab of Julius Brennecke has revealed how PIWI proteins kickstart transposon silencing in reproductive cells.

The findings are published in Molecular Cell: www.sciencedirect.com/science/arti...

09.09.2025 08:57 — 👍 22    🔁 9    💬 0    📌 2

is there data supporting your statement for this call? thanks :)

14.09.2025 11:25 — 👍 1    🔁 0    💬 1    📌 0
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is the US percentage for outgoing country of applicants significantly higher than last year?

14.09.2025 11:21 — 👍 2    🔁 0    💬 2    📌 0
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is the US percentage for outgoing country of applicants significantly higher than last year?

14.09.2025 11:20 — 👍 2    🔁 0    💬 1    📌 0
This is figure 2, which shows M. ibericus queens lay males from two different species.

This is figure 2, which shows M. ibericus queens lay males from two different species.

Living organisms are assumed to produce same-species offspring. A study in Nature reports a shift from this norm in Messor ibericus, an ant that lays individuals from two distinct species. go.nature.com/3V68MP0 🧪

13.09.2025 01:13 — 👍 35    🔁 12    💬 3    📌 1
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Microtubules in Asgard archaea Discovery of heterodimeric, microtubule-forming tubulins in Asgard archaea, the closest known relatives of eukaryotes, reveals snapshots of microtubule evolution.

Microtubules in Asgard archaea (h/t @lanzen.bsky.social) www.cell.com/cell/fulltex... #jcampubs

11.09.2025 16:04 — 👍 30    🔁 10    💬 1    📌 2
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Rapid protamine evolution suppresses meiotic drive in Drosophila Many animal species replace histones with protamines during spermatogenesis. Despite their importance for sperm function, protamines rapidly evolve in many species; the biological causes behind their ...

www.biorxiv.org/content/10.1...

08.09.2025 00:47 — 👍 1    🔁 0    💬 0    📌 0
An image of the full Moon with a thick, fuzzy black line across the middle. The caption says, "Flat Earth eclipses are awesome".

An image of the full Moon with a thick, fuzzy black line across the middle. The caption says, "Flat Earth eclipses are awesome".

I hope everyone on the other side of the Earth is enjoying the total lunar eclipse! Except for flat Earthers.

07.09.2025 18:18 — 👍 325    🔁 44    💬 16    📌 1
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Yesterday me and my lab celebrated #20years @mpi-cbg.de. There is a lot to say about that but the pictures from the event tell it better. Thanks city of #Dresden for the nice fireworks. That was unexpected. 10 more years or so? #LoPaTs 💕

07.09.2025 07:54 — 👍 116    🔁 14    💬 7    📌 1
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Flies evolved a shock-absorber tissue used during embryonic development The role of tissue that forms between the head and trunk of a fly embryo has been unclear. It turns out that it absorbs forces when nearby cells move and divide.

www.nature.com/articles/d41...

04.09.2025 20:26 — 👍 2    🔁 0    💬 0    📌 0
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We are all super happy and proud to see our work on the function and evolution of the #cephalic #furrow published in @nature.com. Let me say a few things about the background and history of this work on the #Evolution_of_Morphogenesis (1/12)

04.09.2025 08:21 — 👍 346    🔁 119    💬 16    📌 8
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The aging factor EPS8 induces disease-related protein aggregation through RAC signaling hyperactivation - Nature Aging Aging is a risk factor for neurodegenerative diseases associated with protein aggregation. Here the authors identify age-related hyperactivation of EPS8/RAC signaling in C. elegans as a driver of path...

🚨 New from our lab: Here we explored how aging contributes to harmful protein aggregation in diseases like Huntington’s & ALS.
The culprit? An overlooked aging factor — EPS8 and RAC signaling. #Aging #Longevity #Proteostasis #ALSResearch
🧵
www.nature.com/articles/s43...

03.09.2025 09:19 — 👍 28    🔁 15    💬 1    📌 3
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Private tour of the Louvre is a special treat. They were vacuuming the Sphinx. You may not have seen a Sphinx being brushed, so I am sharing.

03.09.2025 08:36 — 👍 106    🔁 9    💬 3    📌 0

Our new preprint is out !
We uncover how adult Drosophila muscles respond to injury through a coordinated dialogue between hemocytes, tracheal cells, and muscles.
Check it out and please share
@igdrennes.bsky.social

30.08.2025 15:47 — 👍 17    🔁 14    💬 0    📌 0

The chromatin remodeller CHD4 controls both nucleosome integrity and transcription factor binding to promote activity of active regulatory elements and to prevent activation of silent enhancers https://www.biorxiv.org/content/10.1101/2025.08.29.672645v1

30.08.2025 07:18 — 👍 13    🔁 3    💬 0    📌 1
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Excited to see this published with additional data following our preprint a while back. Cool combination (in our biased view) of controlled TF expression and machine learning to decode chromatin sensitivity. www.sciencedirect.com/science/arti....

07.08.2025 16:20 — 👍 114    🔁 49    💬 2    📌 3

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