Mark D. Garfinkel, Ph.D.'s Avatar

Mark D. Garfinkel, Ph.D.

@mdgarfinkel.bsky.social

"Native New Yorker, adoptive Chicagoan, 24-year veteran of being a stranger in a strange land." Drosophila (fly) person. Childless cat man. Cinema buff. "Fascinated by everything except how to dress," as Matt Groening would put it.

488 Followers  |  1,247 Following  |  1,570 Posts  |  Joined: 24.11.2024  |  2.2017

Latest posts by mdgarfinkel.bsky.social on Bluesky

Entire creation of new data that has no bearing upon any histological relevance. Remember LLM models are not open and we have no understanding of what NeuN, GFAP, or DAPI means in biological space within the LLM.

This is nonsense. But it looks at first blush as "real" to the uninformed.

Scary.

24.11.2025 19:51 โ€” ๐Ÿ‘ 25    ๐Ÿ” 7    ๐Ÿ’ฌ 4    ๐Ÿ“Œ 0

Could you list some of these image-forensics tools for those of us who donโ€™t vet microscopy on a regular basis?

Thanks.

24.11.2025 23:17 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Perhaps a fine point: proxy wars are especially despicable.

Both the Shadows and the Vorlons depended upon genetic _and_ social engineering other sentient species in the pursuit of their astro/galacto-political machinations.

Neither the USSR nor the USA during the Cold War were that manipulative.

24.11.2025 22:59 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

_Star Trek: Deep Space Nine_ evolved into a fairly dark depiction of interstellar war, especially in the later seasons. Nogโ€™s Starfleet service & injury, Section 31 tactics, & the Federation plan to commit genocide against the Changlings, are examples.

For REALLY dark politics thereโ€™s _Babylon 5._

24.11.2025 22:38 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Doug Jones for AL Governor is operational on ActBlue!

To paraphrase old-school machine politics for todayโ€™s grassroots-driven world, โ€œdonate early, donate often.โ€

Also โ€” โ€œvolunteer early, volunteer often.โ€

#Alabama Democrats need more than supportive social media posts to win.

#DougForAlabama

24.11.2025 21:58 โ€” ๐Ÿ‘ 3    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Wait, which? The five POTA films beginning with Heston in 1968, the one-off by Tim Burton in 2001, or the current four-film reboot series?

24.11.2025 21:46 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Doug Jones for AL Governor is operational on ActBlue!

To paraphrase old-school machine politics for todayโ€™s grassroots-driven world, โ€œdonate early, donate often.โ€

Also โ€” โ€œvolunteer early, volunteer often.โ€

Democrats in #Alabama wonโ€™t win with only supportive social media posts.

#DougForAlabama

24.11.2025 21:42 โ€” ๐Ÿ‘ 5    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Doug Jones for AL Governor is operational on ActBlue!

To paraphrase old-school machine politics for todayโ€™s grassroots-driven world, โ€œdonate early, donate often.โ€

Also โ€” โ€œvolunteer early, volunteer often.โ€

Democrats in #Alabama wonโ€™t win with only supportive social media posts.

#DougForAlabama

24.11.2025 21:41 โ€” ๐Ÿ‘ 2    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Doug Jones for AL Governor is operational on ActBlue!

To paraphrase old-school machine politics for todayโ€™s grassroots-driven world, โ€œdonate early, donate often.โ€

Also โ€” โ€œvolunteer early, volunteer often.โ€

Democrats in AL wonโ€™t win with only supportive social media posts.

#DougForAlabama

24.11.2025 21:31 โ€” ๐Ÿ‘ 2    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Doug Jones for AL Governor is operational on ActBlue!

To paraphrase old-school machine politics adapted for todayโ€™s grassroots-driven world, โ€œdonate early, donate often.โ€

Also โ€” โ€œvolunteer early, volunteer often.โ€ Democrats in AL wonโ€™t win with only supportive social media posts.

#DougForAlabama

24.11.2025 21:05 โ€” ๐Ÿ‘ 33    ๐Ÿ” 11    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

I just checked โ€” Doug Jones for AL Governor is operational on ActBlue!

To paraphrase old-school machine politics, โ€œdonate early, donate often.โ€

24.11.2025 20:30 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Itโ€™s almost enough to make one quit social media altogether and make friends the old-fashioned way โ€” IRL book clubs, local theatrical productions & concerts, neighborhood coffee shop & indie cinema house, and social service organizations like Habitat for Humanity & political activist groups, etc.

24.11.2025 20:20 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

If Iโ€™m reading this correctly it also means that the absolutely best grant applications based on scoring cannot be funded _solely_ on that basis. Some other justification need be provided (and documented) โ€” such as โ€œconsistent with the presidentโ€™s political agenda.โ€

Ongoing political hackery!

24.11.2025 18:40 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

How about posting a conventional URL for the registration? (And calibrating the time in UTC offset.)

Thanking you in advanceโ€ฆ

24.11.2025 18:15 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

No, actually Jones defeated Moore in a special election in 2017 to fill the Senate seat Jeff Sessions vacated when Trump named him as AG. (He was later replaced by Bill Barr.)

Tuberville defeated Jones in 2020 for a full term when Trump was running for re-election against Biden.

24.11.2025 18:01 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Back in the heyday of Usenet, spelling flames were generally considered cheap shots.

Besides, shellfish are _trayfe._

24.11.2025 17:15 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

โ€œFascinating,โ€ said the sagacious Mr. Spock.

โ€œThey have hop-offs, while 21st-Century North American human males competed for mates with outsized SUVs and Cybertrucks. The latter proved especially maladaptive for sexual selection.โ€

He proudly remembered his prowess with the lirpa and the ahn-woon.

24.11.2025 16:10 โ€” ๐Ÿ‘ 3    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

โ€œSometimes being first is not enough.โ€
โ€” Jealous Mouse disparaging the lowly Fly

24.11.2025 11:59 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

I was once asked if I knew how many books I owned. I answered in terms of linear-feet of bookshelves that were full, to which I added the vertical height of stacked, unshelved, books.

โ€œโ€ฆand then there are the cartons of paperbacks in storageโ€ฆโ€ is what ended the conversation.

24.11.2025 11:29 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

This is a newly politicized โ€œSchedule Fโ€-type position? So we will be seeing more of these demotions & reassignments.

24.11.2025 11:09 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
The Putin-Witkoff Plan Worsens the War Five Reasons the US should not help Russia subjugate Ukraine

We have a US administration trying to bully Ukrainians into accepting Russiaโ€™s proposal that their sovereignty be undone. Aside from the naked injustice of this, there are five basic practical reasons why it would make the world far more dangerous.
(video)
snyder.substack.com/p/the-putin-...

21.11.2025 21:11 โ€” ๐Ÿ‘ 2408    ๐Ÿ” 906    ๐Ÿ’ฌ 50    ๐Ÿ“Œ 35
Preview
Trump Has a Recipe for War and Corruption, Not Peace Who would benefit from the White Houseโ€™s 28-point proposal for Ukraine?

This is not a peace plan. It is a proposal that weakens Ukraine and divides America from Europe, preparing the way for a larger war in the future. In the meantime, it benefits unnamed Russian and American investors, at the expense of everyone else.
www.theatlantic.com/ideas/2025/1...

22.11.2025 11:11 โ€” ๐Ÿ‘ 9194    ๐Ÿ” 4257    ๐Ÿ’ฌ 324    ๐Ÿ“Œ 309

In the 1980s when HHMI got started, the wiseguy comment was โ€œthe rich get richer, and the poor get to teach.โ€

Nothingโ€™s changed in forty years, has it?

23.11.2025 19:11 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Preview
RFK Jr. Says He Instructed CDC to Change Vaccines and Autism Language on Website In an interview, Health Secretary Robert F. Kennedy Jr. cited gaps in vaccine safety research. His critics say he is ignoring a larger point: Vaccines save lives.

Breaking News: Robert F. Kennedy Jr. said he personally instructed the CDC to abandon its position that vaccines do not cause autism. The move underscores his determination to challenge scientific orthodoxy โ€” in this case, that vaccines save lives โ€” and bend the health department to his will.

21.11.2025 18:56 โ€” ๐Ÿ‘ 1713    ๐Ÿ” 777    ๐Ÿ’ฌ 843    ๐Ÿ“Œ 751

Every thread displaying โ€œdialogueโ€ with Grok is a potent reminder that I was right not to waste any of my precious finite time with ChatGPT and its imitators.

21.11.2025 19:59 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

I had some experience with DIY OCR in the early 1990s. Colleagues sent printed matter that I scanned on a 300dpi flatbed. It might have been an Adobe program I used, I donโ€™t remember for sure, but the manual cleanup was very tedious. IIRC, punctuation in bibliographical citations got badly mangled.

21.11.2025 19:46 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Hallmark announced its holiday movies, but C-SPAN remains silent ๐Ÿค” Here are some suggestions:
1) Miracle on the 218th signature
2) A Muppets Christmas Conference Committee
3) It's a wonderful shutdown
4) Rudolph the red-nosed (continuing) resolution
5) ยกFeliz Filibuster! ๐ŸŽ„

21.11.2025 17:01 โ€” ๐Ÿ‘ 9    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

As a reminder, this is _exactly_ what โ€œgoing wild on healthโ€ looks like. Trump promised it; RFK Jr. et al. is delivering it. Russ Vought is gleefully delighting in it: โ€œEverything is proceeding as I had foreseen.โ€

This isnโ€™t a governing party, itโ€™s a death/murder cult.

21.11.2025 17:17 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
A male Annaโ€™s hummingbird at the door. So nosy! ๐Ÿคฃ

A male Annaโ€™s hummingbird at the door. So nosy! ๐Ÿคฃ

Earlier today, I was notified that someone was at my door.

This is who it was:

21.11.2025 00:59 โ€” ๐Ÿ‘ 45542    ๐Ÿ” 7151    ๐Ÿ’ฌ 828    ๐Ÿ“Œ 319

I started reading the text of the patent. Itโ€™s a OCR scan of the original document and has some amusing (IMO) uncorrected errors. Its language of โ€œagedโ€ material oddly reminded me of how one might describe a fine wine, bourbon, or single-malt Scotch.

21.11.2025 17:00 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

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