SickKids Cardiac Precision Medicine

⏳ Less than 2 weeks to go!
Cardiac Precision Medicine in the 21st Century 🫀✨

Huge thank you to our sponsors:
🔶 Gold: Illumina
🔷 Silver: PacBio (@pacbio.bsky.social), Sanofi, Standard BioTools
🔸 Bronze: Edgewise Therapeutics, Bristol Myers Squibb

Join us at the Cardiac Precision Medicine in the 21st Century Conference for a special session sponsored by Illumina

🗓 Thurs. Oct 30 | 🕢 7:30 AM | 📍SickKids

🎙 Dr. David Lanfear
🧬 Making Precision More Practical: Design and Results of the CardioSeq Clinical Trial

Cardiac Precision Medicine in the 21st Century

💊 Session 5: Precision Therapies on the Horizon

Featuring:
Mansoor Husain – Metabolic Therapies in Heart Failure
Tamorah Lewis – Pharmacogenetic-Guided Therapy
Nimesh Desai – Genotype-Guided Surgery for Aortopathy

cardiacprecisionmedicine.com

Cardiac Precision Medicine in the 21st Century
🧬 Session 5: Precision Therapies on the Horizon

Feat:
Dr. Ronald Cohn – Gene Therapy
Dr. Gregor Andelfinger –Targeted Therapy for Rasopathies
Dr. Joseph Rossano – Cardiomyopathy Therapies

cardiacprecisionmedicine.com

Cardiac Precision Medicine in the 21st Century
💡 AI & Digital Health – Applications in Healthcare

Dr. Yvonne Bombard – Delivering Precision Medicine Digitally
Dr. Danton Char – Ethics in Healthcare AI
Dr. Etienne Richer – Global Genomics Perspective

Learn more: cardiacprecisionmedicine.com

⏳ Voting closes soon - have you cast your vote for the Best #Cardiovascular Science of the Decade #Awards?

Check your inbox & rank the top papers in:
🔬Basic Science
🩺Clinical Science
💡Translational Science / Invention

Learn about the nominees: tedrogersresearch.ca/best-cardiov...

📢New! Yield on Reinterpretation of Genetic Variants in Pediatric Cardiomyopathy

🧬 1 in 5 kids with CMP had a clinically actionable change in genetic variant classification on follow-up.
🔍 Reinterpretation = better family screening & care.

📖Read: www.ahajournals.org/doi/10.1161/...

Cardiac Precision Medicine in the 21st Century
💡 Session: AI & Digital Health – Applications in Healthcare

Dr. Mark Friedberg – AI in Cardiac Imaging
Dr. Osami Honjo – 3D Printing in Surgery
Dr. Cedric Manlhiot – Digital Health & EHR Integration

Learn more: cardiacprecisionmedicine.com

Cardiac Precision Medicine in the 21st Century
🧬Beyond Genomics to Multi-Omics

This week’s featured speakers:
Dr. Diana Baralle - Blood-Based Transcriptomics
Dr. Kartik Chundru (@chundru.bsky.social) – Long-Read Sequencing in Brain & Heart

Learn more: cardiacprecisionmedicine.com

Cardiac Precision Medicine in the 21st Century
🧬Beyond Genomics to Multi-Omics

Featuring:
Dr. Sushma Reddy – Proteomic Profiling
Dr. Perry Elliott – Multi-Omics in Cardiomyopathies
Dr. Marie-Alexandre Chaix – Metabolomics in CHD

Learn more: cardiacprecisionmedicine.com

Good news - our 10th Annual #HFSymposium is now accredited!

Join as we celebrate a decade of healthier hearts and bring together the #TRCHR community to discuss new research, engage in collaborative workshops, and participate in a social networking hour!

🎟️ tedrogersresearch.ca/symposium/

Cardiac Precision Medicine in the 21st Century
🫀Precision Care for Cardiomyopathy – A Spotlight on HCM
Featuring:
Dr. Barbara Cifra – Personalized Exercise
Dr. Daniel Franklin – Smart Wearables
@lisasalberg.bsky.social – Advocacy in HCM

Learn more: cardiacprecisionmedicine.com

Cardiac Precision Medicine in the 21st Century Conference
🫀Precision Care for Cardiomyopathy – A Spotlight on HCM

Featuring:
Dr. Seema Mital – Diastolic Dysfunction: A biological Lens
Tanya Papaz – Sudden Death Risk Prediction

Learn more: cardiacprecisionmedicine.com

Cardiac Precision Medicine in the 21st Century
Precision Care for Cardiomyopathy – A Spotlight on HCM

Featuring:
Dr. Alyssa Power – Natural History of Pediatric HCM
Dr. Steve Ommen – Personalizing Guidelines
Dr. Martin Maron– Adult Targeted Therapies

🔗 Learn more: cardiacprecisionmedicine.com

🎤 Speaker Spotlight: Cardiac Precision Medicine in the 21st Century
🧬Genomic Discoveries in Cardiac Disease – The Next Frontier

Featuring:
Rafik Tadros- Polygenic Risk Scores
Hiroyuki Yamagishi– Asian Genomic Perspectives
Nathaly Sweeney– Newborn Genome Sequencing

cardiacprecisionmedicine.com

🎤Speaker Spotlight: Cardiac Precision Medicine in the 21st Century

🧬Genomic Discoveries in Cardiac Disease–The Next Frontier

Featuring:
🔹 Dr. @robertlesurf.bsky.social–AI & the Genome’s Dark Matter
🔹 Dr. @fritzroth.bsky.social–Missense Variants in LDLR

🔗Register: cardiacprecisionmedicine.com

Speaker Spotlight: Cardiac Precision Medicine in the 21st Century!

📅 Oct. 29–31 |📍Toronto, Canada (Hybrid)

Featuring amazing SickKids faculty who will be leading the AI and Digital Tools in Precision Medicine Workshop!

🔗Learn more: cardiacprecisionmedicine.com

@robertlesurf.bsky.social

Systems biology approaches investigating mitochondrial dysfunction in cyanotic heart disease: a systematic review Cyanotic congenital heart disease (CCHD) affects over 3 million individuals globally and can progress to heart failure. Mitochondrial dysfunction is w…

Systematic review in @ebiomedicine.bsky.social reveals how systems biology uncovers mitochondrial dysfunction in cyanotic congenital heart disease.

🧬 Identifies 9 key mitochondrial genes
💊 Highlights potential therapies
📊 Links dysfunction to heart failure risk

sciencedirect.com/science/arti...

Speaker Spotlight: Cardiac Precision Medicine in the 21st Century!

📅 October 29–31 |📍Toronto, Canada (Hybrid)

Featuring amazing @sickkidsto.bsky.social faculty who will be leading the Genomic Tools for the Clinician Workshop!

🔗Learn more and register: cardiacprecisionmedicine.com

🚨Just 4 days left to submit your abstract for the Cardiac Precision Medicine in the 21st Century Conference — happening this October in Toronto!

Showcase your research. Shape the future of precision cardiac care. 💡🧬🫀

🔗 Learn more & submit now: cardiacprecisionmedicine.com

⌛Just over a week left!

Submit your abstract for the Cardiac Precision Medicine in the 21st Century Conference 🫀

📅 Oct 29–31, 2025 | Toronto

Showcase your research + compete for Best Abstract Award!
🔗 cardiacprecisionmedicine.com

#CardiacPrecision #Genomics #callforabstracts

🧬 Call for Abstracts: Cardiac Precision Medicine in the 21st Century!

Submit your research for the International Cardiovascular Genomic Medicine & SickKids Cardiac Precision Medicine Conference 🫀

🔗cardiacprecisionmedicine.com

#CardiacGenomics #PrecisionMedicine #CallForAbstracts

🚨 NEW Publication 🚨

The tools of #StemCellResearch shape its impact, but current iPSC lines lack genetic diversity.

Dr. James Ellis and global partners call for inclusive reference lines that better reflect the world’s population.

Read more: ow.ly/Hauj50W4Ipa

🚨 Last call for Early Bird Registration! 🚨

Join global leaders in #CardiacPrecisionMedicine this Oct 29–31 in Toronto (SickKids) or virtually

🔬 Chaired by: Dr. Seema Mital
🎤 Keynotes: Dr. Sharlene Day & Dr. Dr. Ma’n Zawati
🕒 Early Bird Registration ends June 1!
👉 web.cvent.com/event/4987df...

🚨 Early Bird Registration ends June 1!

Join us in Toronto (or virtually) for Cardiac Precision Medicine in the 21st Century Conference 🫀🧬
📅 Oct 29–31, 2025
🔬 Genomics, multiomics, AI, Digital Health & more
🎤Keynotes: Dr. Sharlene Day & Dr. @mhzawati.bsky.social

👉 cardiacprecisionmedicine.com

Long-read genome sequencing increases genomic yield in congenital heart disease Congenital heart disease (CHD) is the most common birth defect. We performed Illumina short-read genome sequencing (GS) of 1,101 probands, which identified a genetic cause in 16% of cases. We performe...

🚨 Preprint alert! @medrxivpreprint.bsky.social

Long-read genome sequencing boosts diagnostic yield in congenital heart disease, uncovering variants missed by short-read sequencing.

Great work Seema Mital, @robertlesurf.bsky.social, Anjali Jian, Nour Hanafi et al!

www.medrxiv.org/content/10.1...

What’s it really like to go through a #HeartTransplant?
Patients, caregivers & clinicians came together to
share their experiences. Their stories & key information can be found at A Heart’s Journey, @trogersresearch.bsky.social's NEW transplant resource: ourhearthub.ca/heart-transp... #HFAW

Heart Centre Biobank – Heart Centre Biobank Welcome to the Heart Centre Biobank A provincial and international research network aimed at improving outcomes in heart disease through enhanced prevention and treatment. Happier Children, Healthier...

The Heart Centre Biobank, an Ontario-wide registry, is at the heart of the SickKids Cardiac Precision Medicine Program. Providing invaluable data and samples from over over 10,000 children and adult participants to drive precision medicine forward.🫀

Learn more: theheartcentrebiobank.com

The latest issue of the Heart Centre Biobank Registry Participant newsletter is now available! Stay up to date with the latest discoveries. We thank all Heart Centre Biobank participants—your contributions make these discoveries possible! ❤️

Check it out: theheartcentrebiobank.com/wp-content/u...

✨Early Bird Registration is NOW OPEN!✨

Join us in Toronto this October for the International Cardiovascular Genomic Medicine & SickKids Cardiac Precision Medicine Conference. Don't miss out on the latest advancements in cardiac precision medicine! 🫀🧬

cardiacprecisionmedicine.com