Nathan A. Tanner

OOOPS! UPDATE: Two HHS officials tell me that disease detectives, measles response officers, global health officials and the MMWR staff were laid off by mistake and will be reinstated. But Washington office is still RIFed

BREAKING: Friday night massacre underway at CDC. Doznes of "disease detectives," high-level scientists, entire Washington staff and editors of the MMWR (Morbidity and Mortality Weekly Report) have all been RIFed and received the following notice:

Move over Marie Cutie, Fred Sanger, etc., the new most Nobel leader is……MJ Research Thermocycler, with, like 30!

Headline from an article in Nature this week that states "Prizes must recognize machine contributions to discovery. The future of science will be written by humans and machines together. Awards should reflect that reality."

Lol the Nobels can't even acknowledge women's contribution to discovery. But sure let's acknowledge The Machines.

gold standard science

Today my @nytimes.com colleagues and I are launching a new series called Lost Science. We interview US scientists who can no longer discover something new about our world, thanks to this year‘s cuts. Here is my first interview with a scientist who studied bees and fires. Gift link: nyti.ms/3IWXbiE

in the UT band we did a show with Greenwood at a home football game, it felt old and tired and got a tepid response…in 2002

I was in the U. Tennessee marching band and we did a show with Lee Greenwood to tepid response at a home game…in 2002

actual good news

Trevor Lawrence reclining

Game-winning touchdown

This serves absolutely no purpose other than to reduce vaccine uptake:
www.reuters.com/business/hea...

Medicine Nobel for researchers who identified immune system’s security guards Mary Brunkow, Fred Ramsdell, and Shimon Sakaguchi discovered regulatory T cells that prevent autoimmune disease

“Anyone who does not have an autoimmune disease, that’s because of these regulatory T cells,” says Markus Feuerer, an immunologist at the Leibniz Institute for Immunotherapy.

www.science.org/content/arti...

good lord it’s not Beowulf it was written in 1935 in very readable English

The NIH ordered me to stop my ‘dangerous’ gain-of-function research. It isn’t dangerous at all Safe gain-of-function research is necessary to identify new treatments for diseases like for tuberculosis — but the NIH has imposed unfounded stops.

This is a great op-ed by Dr. Stanley about the effects of anti-science politicized attacks on "gain-of-function" research. Much of this research poses little risk and has huge benefits for people across the globe. If your research has been affected, please consider writing an op-ed like Dr. Stanley.

Getting 43% of all the math wrong should be no problem for peer review right

this is totally false, I’m 42

not really the point but we did this in 1969 with less computing power than my daughter’s calculator, should say something that he can’t do it today

finally a good LLM

Clinical validation of an AI-based blood testing device for diagnosis and prognosis of acute infection and sepsis - Nature Medicine In a prospective study enrolling 1,222 patients from 22 emergency departments, a device using a machine-learning-based signature of blood mRNAs demonstrated clinically acceptable performance to diagnose bacterial and viral infections and to predict the all-cause need for critical care interventions within 7 days, with benchmark to established biomarkers and risk scores.

Molecular testing for sepsis has a mixed at best track record, this very cool use of RT-LAMP to detect immune mRNA might change that

www.nature.com/articles/s41...

This is why we fund scientists to study things like oyster slobber even if you don’t think it sounds important

New grad students and postdocs come get some NEB swag

www.neb.com/en-us/forms/...

YouTube video by Panda Bear - Topic Take Pills

sounds like youtu.be/ggKdy2n_DXA?...

Hey remember when the CDC dropped 6 of the 8 foodborne illnesses from the nationwide monitoring system in July and one of them was listeria? Mentioning for no particular reason www.nbcnews.com/health/healt...

a true god among men

bsky.app/profile/patr...

LOL actually got money out of this, score

borrowed the wig from a Scarlet Overkill costume

they made city-specific ones, I get the Boston version every commercial break

It’s not just about amino acid similarity, there are a lot of CRISPR claims that do not rely on % homology to SpCas9. The “Open” people presenting theirs as having full FTO is pretty risky in my opinion. From Broad ‘359 for example:

Nothing Looks Cooler Than Not Caring You’re Balding In a polarized culture that demands balding men pick a side, opting for the follicular middle ground is a refreshing act of honesty.

I was asked by @gqmagazine.bsky.social to write a little bit about just going bald in the age of widespread head-shaving and affordable, believable hair transplants...so I did!

golden gate to protein, cells not required