Tencho Tenev's Avatar

Tencho Tenev

@ttenev.bsky.social

Biologist, Senior Staff Scientist at @icrlondon.bsky.social #TNFR and #TLR signaling; #immunogenic cell death; #necroptosis; #innate immunity; #immunotherapy; #cancer

628 Followers  |  726 Following  |  5 Posts  |  Joined: 07.02.2024  |  1.5564

Latest posts by ttenev.bsky.social on Bluesky

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Great two day meeting organised by @icr.ac.uk . Lots of amazing talks and posters that culminated with keynote talk by Erik Sahai @eriksahailab.bsky.social . Well done to organisers.

24.06.2025 15:55 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Tumor cells hijack the mRNA export pathway to obstruct nuclear export of retroelement transcripts for viral mimicry inhibition and immune evasion
www.science.org/doi/10.1126/...

09.04.2025 19:31 β€” πŸ‘ 6    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Effective recognition of double-stranded RNA in human cells does not require activation of the antiviral interferon pathway www.science.org/doi/10.1126/...

09.04.2025 19:28 β€” πŸ‘ 18    πŸ” 6    πŸ’¬ 1    πŸ“Œ 0

We made it to 100! πŸ“’πŸ’― The #ubiquitin and #ubl Starter Pack now includes 100 profiles to follow if you’re interested in any aspect of the field: signalling, structure and biochemistry, biology, mechanisms, proteostasis, TPD, chemical biology… Check out the list and let me know if you are missing.

21.01.2025 11:10 β€” πŸ‘ 32    πŸ” 13    πŸ’¬ 1    πŸ“Œ 1
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Commensal papillomavirus immunity preserves the homeostasis of highly mutated normal skin Sun-damaged normal skin contains many clonal mutations. Son etΒ al. show that commensal papillomaviruses residing in keratinocytes help virus-specific CD8+ TΒ cells detect and suppress the mutant clones...

Amazing role of non-pathogenic viruses in providing a benefit to host through suppression of cancer development www.cell.com/cancer-cell/...

17.01.2025 09:15 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Working with a great team to organize
@keystonesymposia.bsky.social on "#LongCOVID and Other Post-Acute Infection Syndromes #PAIS" #KSLongCOVID26
@patientled.bsky.social @daltmann.bsky.social

August 10-13, 2025 | Santa Fe

Hope to see you there!

keysym.us/KSLongCOVID26

12.01.2025 15:05 β€” πŸ‘ 206    πŸ” 65    πŸ’¬ 10    πŸ“Œ 4
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Divergent paths of mammary gland involution: unveiling the cellular dynamics in abruptly and gradually involuted mouse models - Breast Cancer Research Background Epidemiological studies associate an increase in breast cancer risk, particularly triple-negative breast cancer (TNBC), with lack of breastfeeding. This is more prevalent in African America...

Weekend paper to read:
doi.org/10.1186/s130...

10.01.2025 09:09 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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BBC Four - Royal Institution Christmas Lectures, 2024: Chris van Tulleken - The Truth About Food, From Taste Buds to Toilet Dr Chris van Tulleken explores the incredible journey food takes through our bodies.

What we eat? Royal Institution Christmas Lectures in three episodes starting soon.
www.bbc.co.uk/programmes/m...

29.12.2024 20:12 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

After 11months on this platform, so happy to see the momentum finally happening!
Let’s repeat a proper introduction:
My lab studies how the #Microbiome together with #Nutrition influence #Development and Juvenile #Physiology using #Mice and #Drosophila as models… we also do lot’s of #Microbiology

23.11.2024 06:52 β€” πŸ‘ 69    πŸ” 5    πŸ’¬ 3    πŸ“Œ 0
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Are you ready for this? We are on Bluesky too!!! Follow the account of NATURE CELL BIOLOGY below!
bsky.app/profile/natu...

20.11.2024 17:46 β€” πŸ‘ 94    πŸ” 30    πŸ’¬ 2    πŸ“Œ 0

πŸ‘‹ fellow immunologists, it’s a pleasure to be with you all on bsky! I work on type I #interferons, I figured it would be neat to have a starter pack for those of us working on all things IFN! I’ll keep adding to it, let me know if you want to be included! #immunology #immunosky go.bsky.app/71vKZJA

20.11.2024 07:36 β€” πŸ‘ 62    πŸ” 17    πŸ’¬ 26    πŸ“Œ 2

We’ve jumped on board fully here on πŸ¦‹
A starter pack of those working on our favourite cell … the T cell πŸ₯°πŸ™ˆπŸ₯°

If you want an add let us know

go.bsky.app/8B5P25c

19.11.2024 22:03 β€” πŸ‘ 74    πŸ” 26    πŸ’¬ 46    πŸ“Œ 3

Let's bring the #CellDeath community together here on πŸ¦‹

Just get in touch to join this Starter Pack

go.bsky.app/R6mGrKU

16.11.2024 09:41 β€” πŸ‘ 63    πŸ” 44    πŸ’¬ 17    πŸ“Œ 1

Hi Stylianos, that is great news to see many editors of science journals joining Bluesky. It will be great if Nature journals start posting here.

17.11.2024 09:28 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Another day, another million new people have joined Bluesky!

18M users? πŸ™‚β€β†”οΈ 18M friends πŸ™‚β€β†•οΈ

16.11.2024 20:43 β€” πŸ‘ 238316    πŸ” 16761    πŸ’¬ 6569    πŸ“Œ 2018
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PROTAC protein degraders to drug the undruggable enter phase 3 trials Pharmaceutical companies are investing in therapies that target proteins for degradation, with trials ongoing for cancer, autoimmune diseases and neurological disorders.

Good news for #Protacs www.nature.com/articles/d41...

15.11.2024 08:32 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

@ttenev is following 19 prominent accounts